Saturday
2:00 pm - 5:00 pm
Arrival and Check-in
3:30 pm - 3:45 pm
Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm
Regulation of Cytoskeletal Networks
Discussion Leader: Torey Arnold (Boston College, USA)
3:45 pm - 3:55 pm
Yinan Shen (Harvard University, USA)
"Microrheology of Microtubule-Actin-Vimentin Composite Cytoskeletal Networks"
3:55 pm - 4:00 pm
Discussion
4:00 pm - 4:10 pm
Jasmin Imran Alsous (Massachusetts Institute of Technology, USA)
"Coordination of Surface Actomyosin Waves Promotes Proper Tissue Contractions"
4:10 pm - 4:15 pm
Discussion
4:15 pm - 4:25 pm
Arthur Molines (University of California, San Francisco, USA)
"Effects of Cytoplasm Density on Cytoskeleton Dynamics"
4:25 pm - 4:30 pm
Discussion
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Filament Dynamics and Associated Proteins
Discussion Leaders: Charlotte Kelley (Northeastern University, USA) and Jia Wang (National Institutes of Health, USA)
7:30 pm - 7:45 pm
Claire Strothman (Vanderbilt University, USA)
"Kinesins HSET and MCAK Antagonistically Regulate Microtubule Minus-End Catastrophe by Modulating Tubulin Off-Rate"
7:45 pm - 7:50 pm
Discussion
7:50 pm - 8:05 pm
Mu A (Dartmouth College, USA)
"A Complex Containing Lysine-Acetylated Actin and Cyclase-Associated Protein Inhibits the Formin INF2"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Max Jakobs (University of Cambridge, United Kingdom)
"Dynactin Accumulation at Growth Cones Organises Microtubule Polarity in Axons"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Andrew Huehn (Yale University, USA)
"Cofilin Induces Local Changes in the Actin Filament and Severely Disrupts the Actin Intersubunit Interface at the Pointed End of Bound Cofilin"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Matthew Marzo (Colorado State University, USA)
"Pac1/LIS1 Promotes an Open Uninhibited Conformation of Yeast Dynein that Regulates Its Localization and Activity"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:25 pm
Adriana Golding (University of Wisconsin-Madison, USA)
"Direct Observation of Active RhoGTPase Extraction by RhoGDI"
9:25 pm - 9:30 pm
Discussion
Sunday
7:30 am - 8:30 am
Breakfast
9:00 am - 11:00 am
Evolution of the Cytoskeleton / Mentorship Component: Steps to a Fulfilling Career in Science
Discussion Leader: Claire Edrington (McGill University, Canada)
9:00 am - 9:15 am
Gabriella Li (University of Colorado Anschutz Medical Campus, USA)
"Investigating Microtubule Dynamics Across Temperature"
9:15 am - 9:20 am
Discussion
9:20 am - 9:35 am
Courtney Schroeder (Fred Hutchinson Cancer Research Center, USA)
"A Rapidly Evolving Actin-Related Protein Localizes to Critical Actin Structures During Meiosis in the Testis"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Pavan Vedula (University of Pennsylvania, USA)
"Role of Amino Acid Sequence Differences in the Global Intracellular Functions of β- and γ-Actin"
9:55 am - 10:00 am
Discussion
10:00 am - 10:50 am
Joanne Kamens (Addgene, USA)
"Call to Action: Take the Bull by the Horns: Steps to a Fulfilling Career in Science"
10:50 am - 11:00 am
Discussion
11:00 am - 12:30 pm
Poster Session
Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm
Lunch
1:30 pm - 2:30 pm
Cellular Organization and Polarity
Discussion Leader: Akanksha Thawani (Princeton University, USA)
1:30 pm - 1:45 pm
Sivakami Mylvaganam (University of Toronto, Canada)
"A Spectrin-Based Cytoskeleton Confers Unique Properties to the Apical Endothelial Membrane"
1:45 pm - 1:50 pm
Discussion
1:50 pm - 2:05 pm
Siiri Salomaa (Turku Bioscience Centre, University of Turku, Finland)
"SHANK3 Interacts with Actin and Regulates Stress Fibers and Focal Adhesions"
2:05 pm - 2:10 pm
Discussion
2:10 pm - 2:25 pm
Allison Zajac (University of Chicago, USA)
"Shaping the Extracellular Matrix Through Kinesin-3 and Kinesin-1 Driven Polarized Secretion"
2:25 pm - 2:30 pm
Discussion
2:30 pm - 3:00 pm
Evaluation Period
Fill in GRS Evaluation Forms
3:00 pm
Seminar Concludes