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Salivary Glands and Exocrine Biology (GRS)

Gordon Research Seminar

Mapping Salivary and Exocrine Organogenesis: From Cells to Secretion

February 2 - 3, 2019

Chairs Aaron J. Mattingly and Sarah Pringle

Grand Galvez

2024 Seawall Boulevard

Galveston, Texas, United States

Venue and Travel Information

Conference Description

The Gordon Research Seminar (GRS) on Salivary Glands and Exocrine Biology aims to unite highly qualified graduate students, postdoctoral fellows and other scientists with comparable levels of experience and education to discuss novel research findings related to the field of exocrine biology. In this informal setting, junior scientists will be able to present exciting unpublished research through talks and posters, foster collaboration and networking, and learn about future career paths through a mentor career panel.

This year, the GRS will focus on organ structure and function, first highlighting topics encompassing the world of exocrine gland secretion and secretory products before transitioning to the formation of the structural units that make secretion possible.

Related Meeting

This GRS will be held in conjunction with the "Salivary Glands and Exocrine Biology" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.

Conference Program

Saturday
2:00 pm - 5:00 pm	Arrival and Check-in
3:30 pm - 3:45 pm	Introductory Comments by GRC Site Staff / Welcome from the GRS Chair
3:45 pm - 4:30 pm	Keynote Session: Intersections of Secretory Dysfunction and Disease Discussion Leader: Aaron Mattingly (University of California, San Francisco, USA)
3:45 pm - 4:20 pm	Blake Warner (National Institute of Dental and Craniofacial Research, NIH, USA) "Xerostomia as a Complication of Cancer Immune Checkpoint Inhibition"
4:20 pm - 4:30 pm	Discussion
4:30 pm - 6:00 pm	Poster Session
6:00 pm - 7:00 pm	Dinner
7:30 pm - 9:30 pm	Insights into Inflammation and Disease Discussion Leaders: Spencer Dean (School of Dentistry, University of Utah, USA) and Kimberly Jasmer-McDonald (University of Missouri, USA)
7:30 pm - 7:45 pm	Xiaoyan Wang (University Medical Center Groningen, The Netherlands) "Senescence Markers: New Promising Early Diagnostic Biomarkers for Primary Sjögren's Syndrome?"
7:45 pm - 7:50 pm	Discussion
7:50 pm - 8:05 pm	Jeremy Kiripolsky (University at Buffalo, SUNY, USA) "Activation of Multiple Myd88-Dependent Tlr Signaling Pathways Mediate Salivary Gland Inflammation in a Mouse Model of Primary Sjögren's Syndrome"
8:05 pm - 8:10 pm	Discussion
8:10 pm - 8:25 pm	Adam Martin (University of Missouri, USA) "Loss of the P2X7 Receptor for Extracellular ATP Increases Lymphocytic Infiltration of Submandibular Glands in Aging Female Mice"
8:25 pm - 8:30 pm	Discussion
8:30 pm - 8:45 pm	Ana Caroline Costa da Silva (National Institutes of Health, USA) "Damage-Associated Molecular Pattern (DAMP) Signaling: A Possible Trigger for Salivary Gland Graft-Versus-Host Disease?"
8:45 pm - 8:50 pm	Discussion
8:50 pm - 9:05 pm	Esra Amoura (School of Clinical Dentistry, University of Sheffield, United Kingdom) "The Role of CRTC1-MAML2 Fusion Protein in Mucoepidermoid Carcinoma"
9:05 pm - 9:10 pm	Discussion
9:10 pm - 9:25 pm	Alison May (University of California, San Francisco, USA) "CFTR Acts as an Essential Regulator of Exocrine Gland Morphogenesis"
9:25 pm - 9:30 pm	Discussion
Sunday
7:30 am - 8:30 am	Breakfast
9:00 am - 11:00 am	Progenitor Cells, Programming, Regeneration and Secretion Discussion Leaders: Isabelle Lombaert (University of Michigan, USA) and John McKendrick (University of Edinburgh, United Kingdom)
9:00 am - 9:15 am	Paola Serrano Martinez (University Medical Center Groningen / University of Groningen, The Netherlands) "Interaction Between β-Adrenergic and the Notch Signaling in Medication-Induced Hyposalivation"
9:15 am - 9:20 am	Discussion
9:20 am - 9:35 am	Harim Santos (University of Utah, USA) "Laminin 111 Peptides Improve Par-C10 Cell Attachment and Organization"
9:35 am - 9:40 am	Discussion
9:40 am - 9:55 am	Nicholas Moskwa (University at Albany, SUNY, USA) "Collaborative Mesenchyme Is Necessary for Salivary Gland Proacinar Epithelial Organoid Differentiation"
9:55 am - 10:00 am	Discussion
10:00 am - 10:15 am	Callie Brown (University of Utah, USA) "Synergistic Effects of Laminin-1 Peptides, VEGF and FGF9 on Salivary Gland Regeneration"
10:15 am - 10:20 am	Discussion
10:20 am - 10:35 am	Marie Saitou (University at Buffalo, SUNY, USA) "Comparative RNA-Seq Sheds Light on Functional and Evolutionary Differentiation of Human Major Salivary Glands"
10:35 am - 10:40 am	Discussion
10:40 am - 10:55 am	Danielle Wu (University of Texas Health Science Center at Houston, USA) "Building a 3D Salivary Tissue (3D-ST) Replacement for Patients with Xerostomia"
10:55 am - 11:00 am	Discussion
11:00 am - 12:30 pm	Poster Session Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pm - 1:30 pm	Lunch
1:30 pm - 2:30 pm	Mentorship Component: Exploring Career Paths in Science Discussion Leader: Sarah Pringle (University of Groningen, The Netherlands)
1:30 pm - 2:30 pm	Panel Discussion Exploring Career Paths in Science: Academia, Industry and Scientific Writing Agathe Bourgogne (Bellicum Pharmaceutical, Inc., USA) Isabelle Lombaert (University of Michigan, USA) Susan Marriott (BioScience Writers, LLC, USA)
2:30 pm - 3:00 pm	Evaluation Period Fill in GRS Evaluation Forms
3:00 pm	Seminar Concludes

Contributors

Research reported in this publication was supported by the National Institute Of Dental & Craniofacial Research of the National Institutes of Health under Award Number R13DE028494. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

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Salivary Glands and Exocrine Biology

January 26 - 31, 2025

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