Introduction: Proliferative Homeostasis and Aging: G.M. Martin.
Cellular Aging (I) - Cell Cycle Control: G. Gabbiani and J. Campisi, discussion leaders.
J. Pines, "Cell Cycle Control by the Cyclin-Dependent Kinases : How Cyclins are Targeted within the Cell."
S. Shall, "Cellular Aging in Progeroid Syndrome and Isolation of Genes for Cellular Mortalization."
V. Sorrentino, "Gene Expression in Senescent Cells."
Cellular Aging (II) - Transcription Control: S. Shall and R. Sager, discussion leaders.
J. Campisi, "Transcription Repressors and Control of Cell Senescence."
G. Stein, "Deficient Mitogenic Response in Senescent Human Fibroblasts: Alterations in Cell Cycle Proteins and
Second Messenger Molecules."
T. Maciag, "FGF-1-Mediated FGFR-1 Signaling is Impaired by IL-1a-Induced HUVEC Senescence."
Aging and Cancer: G. Stein, discussion leader.
R. Sager, "Novel Genes Involved in Senescence and Cancer."
E. Wang, "Control of Programmed Cell Death for Longevity."
Open for timely topic
Osteoporosis: D. Hamerman, discussion leader.
M. Passeri, "Osteoporosis: A Brief Clinical Overview"
A. Kahn, "Growth Factor Regulated Changes in Bone Cell Progenitor Populations in Aging."
P.D. Delmas, "Pathogenesis of Age-Related Bone Loss."
J. Pfeilschifter, "Cytokines and Bone Turnover in the Aging Skeleton."
Alzheimer's Disease: G.M. Martin and M.T. Ramacci, discussion leaders.
L. Amaducci, "Alzheimer's Disease: A Brief Clinical Overview."
R. Tanzi, "Genetic and Environmental Factors in Alzheimer's Disease."
E.M. Mandelkow, "Tau Protein, Phosphorylation Cascades, and Alzheimer Paired Helical Filament Formation."
J. Carney, "The Role of Free-Radicals in Alzheimer Disease: Pre-Clinical and Clinical Evidence."
Evolution and Experimental Manipulation of Lifespan: J. Vaupel and E. Masoro, discussion leaders.
T. Kirkwood, "Cellular Homeostasis and the Cell Maintenance Network: Models and Predictions."
A. Richardson, "Theoretical Aspects and Manipulation of Lifespan."
Open for timely topic.
Longevity Assurance Genes I: A. McCormick and P. Giacomoni, discussion leaders.
M. Jazwinski, "Longevity-Assurance Genes: Homeostatic Devices in Yeast Longevity."
C. Kenyon, "Regulation of Lifespan in C. elegans."
J. Tower, "Identification and Testing of Candidate Drosophila LAGs."
Longevity Assurance Genes II: T. Johnson, discussion leader.
M. Peacocke, "A Biomarker of Cellular Aging, In Vivo and In Vitro."
R. Miller, "Immune Phenotypes as Candidate Indices of Biological Age."
N. Fabris, "Biomarkers of Aging in the Neuro-Endocrine Immune Domain"
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