Cilia, Mucus & Mucociliary Interactions
Mucociliary clearance is a major defense mechanism in the airways, and deficiencies in this process can lead to severe lung diseases, including cystic fibrosis, asthma, chronic bronchitis, primary ciliary dyskinesia, and pneumonia. In addition, it is a key parameter determining sensitivity to air pollution and cigarette smoke. The fields of cilia, mucus and mucociliary interactions represent different scientific disciplines that are highly relevant to each other, yet rarely combined into a common scientific meeting. The scientific importance of these areas with respect to normal development, physiology and disease has been increasingly recognized in recent years, and advances in basic understanding of ciliary function as well as mucus composition and secretion have increased possibilities for therapeutic intervention in these diseases at the molecular level. There is still much to learn about lung and conducting airway development and differentiation, and how defects in these processes can lead to disease. Similarly, there presently is very little known about how the various components that contribute to mucus, airway lining fluid, and the periciliary layer are synthesized, packaged, released, and interact with cilia. With the development of new techniques and methods over the last several years, there is strong potential to understand these interactions at a level not previously possible. This Gordon Research Conference serves as a forum where basic and clinical researchers from these diverse disciplines can meet, interact, and bring new basic findings to the translational stage, with the ultimate goal of improving diagnosis and treatment for diseases and disorders involving cilia and mucus.
What is a GRC? Gordon Research Conferences (GRC) are 5-day meetings that bring scientists together from around the world to present and discuss unpublished research with other leaders in their field.
This Gordon Research Conference (GRC) series is related to the "Cilia, Mucus & Mucociliary Interactions" Gordon Research Seminar (GRS)
series. Although a related GRS will typically be scheduled in conjunction with its parent GRC each time it meets, that may not always be the case. Refer to the individual meetings in the Meeting History
section below for more details. For more information about the associated Gordon Research Seminar (GRS) series, click here
.What is a GRS? Gordon Research Seminars (GRS) are 2-day meetings that bring graduate students and post-docs together to discuss their cutting edge research among peers and mentors. Each GRS immediately precedes an associated Gordon Research Conference (GRC), and topics addressed at the GRS relate closely to the GRC.