Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Staff / Welcome and Introduction from the Chairs
7:40 pm - 9:30 pm
Keynote Session: Tuning the Behavior of Migrating Cells for Diverse Applications
Discussion Leaders: Rebecca Jones (Princeton University, United States) and Tamas Nagy (University of California, Los Angeles, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:30 pm
Ana-Maria Lennon-Dumenil (Institut Curie, France)
"Migration of Phagocytes: From Fundamentals to Immunotherapy of Cancer"
8:30 pm - 8:40 pm
Discussion
8:40 pm - 9:20 pm
Xavier Trepat (Institute for Bioengineering of Catalonia (IBEC), Spain)
"Engineering Collective Cell Migration, One Cell at a Time"
9:20 pm - 9:30 pm
Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Inflammation and Wound Healing
Discussion Leader: Ana-Maria Lennon-Dumenil (Institut Curie, France)
9:00 am - 9:25 am
Anna Huttenlocher (University of Wisconsin-Madison, United States)
"Real Time Imaging of Cell Migration During Tissue Repair"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Tim Laemmermann (University of Münster, Germany)
"Swarming and Trapping: LTB4 Gradients Shape Neutrophil Dynamics in Tissues"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Sussan Nourshargh (Queen Mary University of London, United Kingdom)
"Neutrophil Transmigration in Vivo: Dynamics and Novel Mechanisms"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizers: Carole Parent (University of Michigan, United States) and Anna Huttenlocher (University of Wisconsin-Madison, United States)
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Pathfinding and Navigation
Discussion Leader: Michael Sixt (Institute of Science and Technology Austria, Austria)
6:00 pm - 6:25 pm
Carole Parent (University of Michigan, United States)
"LTB4 Signaling During Neutrophil Chemotaxis"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Li Yu (Tsinghua University, China)
"The Role of Migrasomes in Directed Cell Migration"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
Short Talk Selected from Poster Abstracts
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Alex Mogilner (Courant Institute of Mathematical Sciences and Department of Biology, New York University, United States)
"Galvanotactic Directionality of Cell Groups Depends on Group Size"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Collective Migration
Discussion Leader: Xavier Trepat (Institute for Bioengineering of Catalonia (IBEC), Spain)
9:00 am - 9:25 am
Ricard Alert (Max Planck Institute for the Physics of Complex Systems, Germany)
"Internal Durotaxis and Asymmetric Shapes of Cell Clusters"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Jocelyn McDonald (Kansas State University, United States)
"Movement in Balance: Managing Cellular Stresses in Collective Cell Migration"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Alpha Yap (University of Queensland, Australia)
"Negotiating the Crowd: Tissue Mechanics and Cell Movement"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Mechanics of Cell Shape and Polarity
Discussion Leader: Alpha Yap (University of Queensland, Australia)
6:00 pm - 6:25 pm
Tobias Meyer (Weill Cornell, United States)
"Gradients of ER-PM Contacts Direct Cell Signaling and Cell Migration"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Alba Diz-Muñoz (European Molecular Biology Laboratory (EMBL), Germany)
"Overcoming Obstacles – How to Train T-Cells to Migrate in Dense Cancerous Tissues"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
Short Talk Selected from Poster Abstracts
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Michael Sixt (Institute of Science and Technology Austria, Austria)
"How Migrating Cells Control Their Shape and Coherence"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Migration in the Context of Developing Tissues
Discussion Leader: Jocelyn McDonald (Kansas State University, United States)
9:00 am - 9:25 am
Danelle Devenport (Princeton University, United States)
"Making Your Skin Crawl: Cell Migration in Confined Epithelial Spaces"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Daria Siekhaus (University of California Los Angeles, United States)
"Understanding the Directionality and Tissue Invasion Capacities of Macrophages"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Caren Norden (Instituto Gulbenkian de Ciência, Portugal)
"How Neurons Navigate in the Vertebrate Retina: A Matter of Processes and Attachments"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Cytoskeletal Dynamics and Force Generation
Discussion Leader: Laura Machesky (University of Cambridge, United Kingdom)
6:00 pm - 6:25 pm
Guillaume Montagnac (Institut Gustave Roussy, France)
"Associative Memory in Cancer Cells"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Florian Schur (Institute of Science and Technology Austria, Austria)
"A Molecular Atlas of the Lamellipodial Cell Motility Machinery"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
Short Talk Selected from Poster Abstracts
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Pere Roca-Cusachs (Institute for Bioengineering of Catalonia, Spain)
"Regulating Force Transmission and Signaling from the ECM to the Nucleus"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Thursday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Election of the Next Vice Chair(s)
9:00 am - 12:30 pm
Migration and the Metastatic Cascade
Discussion Leader: Guillaume Montagnac (Institut Gustave Roussy, France)
9:00 am - 9:25 am
Laura Machesky (University of Cambridge, United Kingdom)
"Eating and Walking- How Cancer Cells Fuel their Invasive Migration"
9:25 am - 9:35 am
Discussion
9:35 am - 10:00 am
Kevin Cheung (Fred Hutchinson Cancer Center, United States)
"Cell and Tissue Transition States Regulating Collective Invasion and Metastatic Dissemination"
10:00 am - 10:10 am
Discussion
10:10 am - 10:20 am
Short Talk Selected from Poster Abstracts
10:20 am - 10:25 am
Discussion
10:25 am - 10:55 am
Coffee Break
10:55 am - 11:20 am
Victoria Sanz-Moreno (The Institute of Cancer Research, United Kingdom)
"Biochemical Adaptations in Migrating Metastatic Cancer Cells"
11:20 am - 11:30 am
Discussion
11:30 am - 11:40 am
Short Talk Selected from Poster Abstracts
11:40 am - 11:45 am
Discussion
11:45 am - 11:55 am
Short Talk Selected from Poster Abstracts
11:55 am - 12:00 pm
Discussion
12:00 pm - 12:10 pm
Short Talk Selected from Poster Abstracts
12:10 pm - 12:15 pm
Discussion
12:15 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:30 pm
Free Time
4:30 pm - 6:00 pm
Poster Session
6:00 pm - 8:00 pm
Diverse Modes of Cell Motility
Discussion Leader: Danelle Devenport (Princeton University, United States)
6:00 pm - 6:25 pm
Anna Franz (University College London, United Kingdom)
"Swimming in the Crowd: Drosophila Adipocytes on the Move"
6:25 pm - 6:35 pm
Discussion
6:35 pm - 7:00 pm
Katrina Velle (University of Massachusetts Dartmouth, United States)
"A Relative of the “Brain-Eating Amoeba” Crawls Quickly and Persistently through Confined Environments by Blebbing"
7:00 pm - 7:10 pm
Discussion
7:10 pm - 7:20 pm
Short Talk Selected from Poster Abstracts
7:20 pm - 7:25 pm
Discussion
7:25 pm - 7:50 pm
Kirsty Wan (University of Exeter, United Kingdom)
"Bioelectric Control of Motility in Single-Celled Eukaryotes"
7:50 pm - 8:00 pm
Discussion
8:00 pm - 9:00 pm
Dinner
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure