Sunday
2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm - 7:00 pm
Dinner
7:30 pm - 7:40 pm
Introductory Comments by GRC Site Staff / Welcome from the GRC Chair
7:40 pm - 9:30 pm
Keynote Session: A Disrupting Technology
Discussion Leader: Jamshid Karimov (Cleveland Clinic, United States)
7:40 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Abbas Ardehali (UCLA, United States)
"Ex-vivo Heart Perfusion in Standard Donor Hearts: Lessons Learned and not Learned"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Filip Rega (University Hospitals Leuven, Belgium)
"Perfused Cold Preservation of the Heart"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Marcus Granegger (Medical University of Vienna, Austria)
"Ex-situ Perfusion and Assessment of Heart Function: Lessons Learned in an Isolated Working Heart Model"
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Michiel Erasmus (UMCG, The Netherlands)
"Measuring Ex-situ LV function in Combination with Cold Oxygenated Perfusion Reconditioning for DCD Hearts"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Monday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Expanding DBD and DCD Donor Heart Utilization for Transplantation Using Extracorporeal Warm Oxygenated Perfusion
Discussion Leader: Carmelo Milano (Duke University, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
Kumud Dhital (SPARSH Hospital, India)
"DCD Lives with Ex-situ Perfusion"
9:35 am - 9:40 am
Discussion
9:40 am - 10:10 am
Simon Messer (Golden Jubilee National Hospital, United Kingdom)
"In or Out? Normothermic Regional Perfusion Versus Direct Procurement for DCD Hearts The role of NRP Between Expanding DCD Donation and Improving Organ Quality."
10:10 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
Jacob Schroder (Duke University Medical Center, United States)
"Utilizing Extended Criteria Heart DBD Hearts for Transplantation – Results of EXPAND Heart trial. Results of the first DCD heart randomized controlled trial."
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Josef Stehlik (University of Utah, United States)
"Overview of the OCS Heart Perfusion (OHP) Registry for DBD and DCD Heart Transplant Outcomes"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Waleed Hassanein (TransMedics, Inc., United States)
"Can we Double Heart Transplant Volume - The Next Frontier"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
3:00 pm - 4:00 pm
The GRC Power Hour™
The GRC Power Hour™ is designed to address diversity and inclusion in the scientific workplace by providing a safe environment for informal and meaningful conversations amongst colleagues of all career stages. The program supports the professional growth of all members of our communities, including ethnicity, race and/or gender identity by providing an open forum for discussion and mentoring.
Organizer: Annemarie Weissenbacher (Medical University of Innsbruck, Austria)
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Ex-Situ Perfusion Over 24 Hours
Discussion Leader: John Fraser (The Prince Charles Hospital, Brisbane Queensland Australia, Australia)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Jorik Amesz (Erasmus MC, The Netherlands)
"We can Revive Slaughterhouse Hearts with Ex-vivo Perfusion"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
Pieter Doevendans (UMC Utrecht, The Netherlands)
"Optimizing Cardiac Perfusion in the Porcine Model Towards Ex-vivo Repair"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:45 pm
Alvaro Rojas-Pena (University of Michigan, United States)
"Plasma is Capable to Restore Endothelial Function."
8:45 pm - 8:50 pm
Discussion
8:50 pm - 9:05 pm
Nathan Palpant (University of Queensland, Australia)
"Adding Cardio-protective Drugs to Extend Safe Perfusion Time"
9:05 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Tuesday
7:30 am - 8:30 am
Breakfast
8:30 am - 9:00 am
Group Photo
9:00 am - 12:30 pm
Reconditioning the Failing Donor Grafts
Discussion Leaders: Maryjane Farr (University of Texas Southwestern Medical Center, United States)
9:00 am - 9:25 am
David Schibilsky (University Medical Center Freiburg, Germany)
"Ex-vivo Perfusion of the Donor Heart for Congenital Heart Transplantation"
9:25 am - 9:40 am
Discussion
9:40 am - 10:05 am
Eric Rytkin (Northwestern University, United States)
"Esmolol Facilitates Prolonged Conduction Preservation in the Langendorff Setup"
10:05 am - 10:20 am
Discussion
10:20 am - 10:50 am
Coffee Break
10:50 am - 11:20 am
Arne Neyrinck (University Hospitals Leuven, Belgium)
"Reconditioning the Donor Prior to Death - Death in DCD"
11:20 am - 11:30 am
Discussion
11:30 am - 11:45 am
Late-Breaking Topic
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Sandro Sponga (Udine University Hospital, Italy)
"Discarded Grafts After Cardiac Ex-Vivo Preservation"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:25 pm
Si Pham (Mayo Clinic Florida, United States)
"Balancing Choice versus Necessity: Surgery in Donor Hearts before Transplantation"
12:25 pm - 12:30 pm
Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Regenerative Medicine Applied to Perfused Grafts
Discussion Leader: Sandra Lindstedt (Lund University, Sweden)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:05 pm
Dawn Bowles (Duke University Medical Center, United States)
"Normothermic Ex-vivo Organ Perfusion and Cardiac Transplantation Gene Therapy"
8:05 pm - 8:10 pm
Discussion
8:10 pm - 8:25 pm
James Mc Cully (Boston Children's Hospital / Harvard Medical School, United States)
"Mitochondrial Transplantation for Myocardial Protection in Ex-situ Perfused Hearts Donated After Circulatory Death"
8:25 pm - 8:30 pm
Discussion
8:30 pm - 8:50 pm
Shaf Keshavjee (University Health Network, Canada)
"Ex-Vivo Perfusions"
8:50 pm - 9:00 pm
Discussion
9:00 pm - 9:20 pm
Jaimin Trivedi (University of Louisville, United States)
"Understanding Gender Inequality in Female Donors Utilization"
9:20 pm - 9:30 pm
Discussion
Wednesday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Immunoregulation and Regenerative Medicine Applied to Machine Perfusion
Discussion Leaders: Andreas Zuckermann (Medical University of Vienna, Austria) and Nir Uriel (Columbia University / Weill Cornell Medicine, United States)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
Late-Breaking Topic
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Darren Freed (University of Alberta, Canada)
"Immunity and Stress Responses Throughout Ex-situ Perfusion."
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Late-Breaking Topic
10:45 am - 10:50 am
Discussion
10:50 am - 11:05 am
Isabelle Ingemansson (Lund University, Sweden)
"Mesenchymal Stem Cells as a Novel Treatment of Injured Donor Grafts for Transplantation"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
Lourdes Chacon Alberty (Texas Heart Institute, United States)
"Exosomal mRNA and microRNA Interaction in Patients with Primary Graft Dysfunction."
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Michelle Mendiola Pla (Duke University, United States)
"Translational Model of Gene Delivery by Ex Vivo Perfusion for Acute Rejection"
11:45 am - 11:50 am
Discussion
11:50 am - 12:00 pm
General Discussion
12:00 pm - 12:30 pm
Poster Previews
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting
Nominations for the Next Vice Chair(s); Complete the GRC Evaluation Forms; Discuss Future Dates and Venue; Election of the Next Vice Chair(s)
7:30 pm - 9:30 pm
Ex-Situ Perfusion of Abdominal Organs: Lessons From Under the Diaphragm
Discussion Leader: Gabriel Oniscu (Edinburgh University, United Kingdom)
7:30 pm - 7:50 pm
Introduction by Discussion Leader
7:50 pm - 8:20 pm
Rutger Ploeg (University of Oxford, United Kingdom)
"The Experience of COPE in Abdominal Transplantation. Establishing QUOD as a national donor biobank and scientific platform in the UK"
8:20 pm - 8:30 pm
Discussion
8:30 pm - 9:00 pm
Annemarie Weissenbacher (Medical University of Innsbruck, Austria)
"Assessment of the Effectiveness of Ex-situ Perfusion of the Abdominal Organs"
9:00 pm - 9:10 pm
Discussion
9:10 pm - 9:30 pm
General Discussion
Thursday
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
The Race Toward Organ Banks
Discussion Leader: Shaf Keshavjee (University Health Network, Canada)
9:00 am - 9:20 am
Introduction by Discussion Leader
9:20 am - 9:35 am
David D'Alessandro (Massachusetts General Hospital, United States)
"Extended Donor Criteria with New Devices for Prolonged Cold Perfusion"
9:35 am - 9:40 am
Discussion
9:40 am - 9:55 am
Lucas Churchill (Paragonix, United States)
"The Heart of Innovation"
9:55 am - 10:00 am
Discussion
10:00 am - 10:30 am
Coffee Break
10:30 am - 10:45 am
Shaf Keshavjee (University Health Network, Canada)
"Organ Banks – Technology, Logistics, Financing, Regulation"
10:45 am - 10:50 am
Discussion
10:50 am - 11:05 am
David Paredes Zapata (Hospital Clinic. University of Barcelona. Barcelona, Spain, Spain)
"Spanish Envision from the Generating Hospitals Perspective on DCD and NRP and Ex-Vivo Perfusion"
11:05 am - 11:10 am
Discussion
11:10 am - 11:25 am
Daniel Tang (INOVA Heart and Vascular Institute, United States)
"Defining an Optimal Donor Heart Ischemic Times in Adult Cardiac Transplantation"
11:25 am - 11:30 am
Discussion
11:30 am - 11:45 am
Yasuhiro Shudo (Stanford University School of Medicine, United States)
"How we Extended Safe Ischemic Time"
11:45 am - 11:50 am
Discussion
11:50 am - 12:05 pm
Xiaoxi Wei (X-Therma Inc, United States)
"Ice-free Deep Hypothermic Preservation - is it Possible to Remove Time from the Equation of Organ Transplant"
12:05 pm - 12:10 pm
Discussion
12:10 pm - 12:30 pm
General Discussion
12:30 pm - 1:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm - 7:00 pm
Dinner
7:30 pm - 9:30 pm
Ex-Situ Perfusion and New Storage Solutions
Discussion Leader: Andreas Zuckermann (Medical University of Vienna, Austria)
7:30 pm - 7:40 pm
Introduction by Discussion Leader
7:40 pm - 7:55 pm
John Fraser (The Prince Charles Hospital, Brisbane Queensland Australia, Australia)
"Principles and Benefits of Cold Non-Ischemic Heart Preservation"
7:55 pm - 8:00 pm
Discussion
8:00 pm - 8:15 pm
David McGiffin (The Alfred Hospital, Monash University, Australia)
"The Australian/New Zealand Trial of Hypothermic Machine Perfusion"
8:15 pm - 8:20 pm
Discussion
8:20 pm - 8:35 pm
Andreas Wallinder (XVIVO Perfusion, Sweden)
"Heart Preservation, More than a Tale of two Temperatures"
8:35 pm - 8:40 pm
Discussion
8:40 pm - 8:55 pm
Rafael Veraza (Vascular Perfusion Solutions, Inc., United States)
"Making Machine Perfusion for Prolonged Cardiac Preservation Simple, Portable, and Accessible."
8:55 pm - 9:00 pm
Discussion
9:00 pm - 9:15 pm
Donald Webber (Bridge To Life, United States)
"Pushing the Limits of Graft Preservation: a Matter of Devices, Perfusion Solutions or Both?"
9:15 pm - 9:20 pm
Discussion
9:20 pm - 9:30 pm
Closing Remarks
Friday
7:30 am - 8:30 am
Breakfast
9:00 am
Departure