Sunday, August 13, 2000 |
2:00-6:00 PM | Arrival and registration |
6:00 PM | Dinner |
| Session 1: CCK discovery, anatomy, evolution and biosynthesis.
Discussion Leader: Jean-Jacques Vanderhaeghen |
7:30-7:45 PM | Welcome and Introduction (GRC staff and Marge Beinfeld) |
7:45-8:15 | Jean-Jacques Vanderhaeghen (CCK past, present and future) |
8:15-8:45 | Anders H. Johnsen (Evolution of the CCK/gastrin family) |
8:45-9:15 | Jens Rehfeld (CCK Biosynthesis) |
9:15- | General Discussion, Opening Reception |
Monday, August 14, 2000 |
7:45-8:30 AM | Breakfast |
| Session 2: Regulation of CCK gene expression, CCK receptor-ligand interaction and intracellular signaling.
Discussion Leader: Jens Rehfeld |
9:00-9:30 AM | Thomas V. Hansen (Regulation of CCK gene expression) |
9:30-10:00 | Dale Mierke (Structural features of the CCK-A/CCK-8 bimolecular complex) |
10:00-10:20 | COFFEE BREAK |
10:20-10:50 | Daniel Fourmy (Structure/function relationships of CCK receptors) |
10:50-11:20 | Robert T. Jensen (CCK A receptor activation of tyrosine kinase phosphorylation cascades) |
11:20-11:50 | Luis Moroder (Molecular Probes for delineation of ligand binding sites of the CCK-B receptor) |
11:50-12:20 | Larry Miller (Insights into the molecular basis of CCK-A receptor binding) |
12:20-12:30 | General Discussion |
12:30 | Conference Photo |
12:30 | Lunch, Afternoon free |
4:30-6:00 PM | Poster Session I |
6:00-7:30 PM | Dinner |
| Session 3: CCK agonists and antagonists.
Discussion Leader: Daniel Fourmy |
7:30-8:00 PM | Jean Martinez (Characterization of non-CCK1 non-CCK2 binding sites for the C-terminal heptapeptide of Gastrin on Human Astrocytic Tumor Cell Lines) |
8:00-8:30 | Elizabeth Sugg (Benzodiazepine CCK-A Agonists for the treatment of Obesity ) |
8:30-9:00 | David Shire (Molecular basis for the contrasting pharmacological profiles of SR 14613 and SR 27897 with the CCK type 1 receptor) |
9:00-9:30 | Christiane Garbay (Design, biological and pharmacological characterization of CCKB receptor subtype-selective agonists and antagonists) |
9:30 | General Discussion |
Tuesday, August 15, 2000 |
7:45-8:30 AM | Breakfast |
| Session 4: Regulation of CCK release, morphology and physiology of CCK interneurons in cerebral cortex, CCK physiology, CCK in neuroprotection and thermoregulation
Discussion Leader: Zsuzanna Wiesenfeld-Hallin |
9:00-9:30 | Wim.E.J.M. Ghijsen (Regulation of CCK release from nerve terminals) |
9:30-10:00 | Yasuo Kawaguchi (Morphology and physiology of CCK inteneurons in the rat prefrontal cortex) |
10:00-10:20 | COFFEE BREAK |
10:20-10:50 | John R. Huguenard (Biphasic effects of CCK on thalamocortical responsiveness) |
10:50-11:20 | Paola Tirassa (CCK and neuroprotection, a role for NGF) |
11:20-11:40 | Zoltan Szelenyi (Possible role of CCK in thermoregulation and fever in rats) |
11:40-12:00 | Short Communication |
12:00-12:30 | General Discussion |
12:30 | Lunch, Afternoon free |
6:00-7:30 PM | Dinner |
| Session 5: CCK peptide knockout mice, Interaction of CCK with 5HT and Dopamine.
Discussion Leader: Valerie Daugé |
7:30-8:00 | Linda Samuelson (CCK expression in teh developing enteric nervous system and enteroendocrine cells) |
8:00-8:30 | Sergio Tanganelli (CCK/Dopamine D2 receptor interactions in the striatum. Biochemical evidence and functional correlates) |
8:30-9:00 | Heidrun Fink (CCK and 5HT) |
9:00-9:30 | Patricia Faris (Interactions between CCK and ondansetron, a 5HT3 receptor antagonist: implications for the pathophysiology of bulimia nervosa) |
9:30-10:00 | Franco Vaccarino (CCK, Anxiety and Dopamine) |
10:00 | General Discussion |
Wednesday, August 16, 2000 |
7:45-8:30 AM | Breakfast |
| Session 6: CCK in Satiety.
Discussion Leader: Nori Geary |
9:00-9:15 | Nori Geary (Introduction) |
9:15-9:45 | Christoph Beglinger (CCK in human satiation) |
9:45-10:15 | Gary Schwartz (CCK Satiety signaling pathway) |
10:15-10:35 | COFFEE BREAK |
10:35-11:05 | Timothy Moran (Eating and weight regulation in OLETF rats lacking the CCK-A receptor) |
11:05-11:35 | Bob Ritter (Dietary adaptation and CCK's satiating action) |
11:35-12:05 | Nori Geary (Estrogen increases CCK's satiating potency) |
12:00-12:30 | General Discussion |
12:30 | Lunch, Afternoon free |
4:30-6:00 | Poster Session II |
6:00-7:30 PM | Dinner |
| Session 7: CCK in Learning and Memory.
Discussion Leader: Franco Vaccarino |
7:30-8:00 | Valerie Daugé (Physiological involvement of CCK-B receptor in attention and/or memory processes in the rat) |
8:00-8:30 | Raymond Nowak (CCK in Learning of material clues in newborn lambs) |
8:30-8:50 | Aaron Weller (CCK and conditioned preferences in infant rats) |
8:50-9:10 | Short Communication |
9:10-9:30 | General DIscussion |
Thursday, August 17, 2000 |
7:45-8:30 AM | Breakfast |
| Session 8: CCK in Anxiety.
Discussion Leader: Jean Jacques Benoliel |
9:00-9:30 | Eero Vasar (The CCK system and anxiety in rodents) |
9:45-10:15 | Diana Koszycki (CCK-B Receptor Polymorphism and Panic Disorder in Humans) |
10:15-10:35 | COFFEE BREAK |
10:35-11:05 | Jean-Michael Le Melledo (CCK-B agonist-induced release of arginine vasopressin and oxytocin in healthy volunteers and psychiatric patients) |
11:05-11:25 | Short Communication |
11:25-11:45 | P. Koefoed (Variation in the CCK and the CCK-B receptor genes in patients with panic disorder-preliminary results) |
11:45-12:00 | General Discussion |
12:00-12:30 | Round Table Discussion (led by Jacques Bradwejn) |
12:30 | Lunch, Afternoon Free |
5:00-6:00 | Business Meeting (Conference evaluation, site and date selection, election of Vice Chair). Run by Chair. |
6:00-8:00 | Banquet |
| Session 9: CCK in analgesia and sexual behavior.
Discussion Leader: Heidrun Fink |
8:00-8:30 | Jean-Jacques Benoliel (CCK/opioid interactions: biochemical aspects) |
8:30-9:00 | Zsuzanna Wiesenfeld-Hallin (CCK/Opioid interaction in the spinal cord in vivo) |
9:00-9:30 | Paul Micevych (CCK-estrogen interactions regulating reproductive behavior) |
9:30- | General Discussion, followed by Closing Reception |
Friday, August 18, 2000 |
7:45 AM | Breakfast and departure |