SUNDAY |
2:00 pm - 9:00 pm | Arrival and Check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | STRUCTURE OF IgSF GLYCOPROTEINS |
| Discussion Leader: Melitta Schachner, Center of Molecular Neurobiology, Hamburg, Germany |
7:30 pm - 8:15 pm | Peter D. Sun, NIAID, NIH, Bethesda, MD
"Structure and function of IgSF receptors on NK cells" |
8:15 pm - 8:45 pm | Gang Song, Y. Yang, J. K. Liu, M. Shimaoko, T. Springer, and J.-H. Wang, The CBR Institute for Biomedical Research, Harvard University, Cambridge, Massachusetts
"Structure and function of ICAM recognition by the integrin αLβ2(LFA-1)" |
8:45 pm - 9:30 pm | Roselyn J. Eisenberg, Univ of Pennsylvania, Philadelphia, PA
"Effects of herpes simplex virus on structure and function of its
receptor nectin-1" |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:45 am | Group Photo |
9:10 am - 12:30 pm | HOMOPHILIC AND HETEROPHILIC BINDING INTERACTIONS
OF IgSF GLYCOPROTEINS |
| Discussion Leader: Jean-Paul Thiery, Institute Curie, Paris, France |
9:10 am - 9:55 am | Melitta Schachner, Center of Molecular Neurobiology, Hamburg, Germany "Recognition molecules of the immunoglobulin superfamily in nervous system development, regeneration and synaptic plasticity" |
9:55 am - 10:40 am | Christian Weber, University Hospital, Aachen, Germany
"Role of heterophilic and homophilic interactions of JAM1 in inflammatory and atherogenic leucocyte recruitment" |
10:40 am | Coffee break |
11:10 am - 11:55 am | Paul Crocker, Wellcome Trust Biocentre, Dundee, Scotland
"Siglecs as sialic acid-dependent adhesion and signaling molecules
in the immune system" |
11:55 am - 12:15 pm | Brian Turner and Kathryn Holmes, University of Colorado Health Sciences
Center, Denver, Colorado
"Structure-based mutational analysis of murine CEACAM1, the receptor
for murine coronavirus MHV" |
12:15 pm - 12:30 pm | Sten Hammarstrom, University of Umea, Sweden
"Carcinoembryonic antigen (CEA) and CEA-related cell adhesion molecule 1
(CEACAM1), apically expressed on human colonic M cells, are potential
receptors for microbial adhesion" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #1 / Reception |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | SIGNAL TRANSDUCTION BY IgSF GLYCOPROTEINS |
| Discussion Leader: John E. Shively, Beckman Research Institute
City of Hope, Duarte, CA, USA |
7:30 pm - 8:15 pm | Jean-Paul Thiery, Institut Curie, Paris, France
"Quantitative determination of cell adhesion: impact on the behavior of cells" |
8:15 pm - 9:00 pm | Vanessa L. Ott and John Cambier, National Jewish Medical and Research Center, Denver, Colorado
"Signaling function of IgSF inhibitory receptors in the immune system" |
9:00 pm - 9:30 pm | Timo K. Van den Berg, J. Alblas, H. Honing, C.R. de Lavalette, and
C.D. Dijkstra, VU Medical Center, Amsterdam, The Netherlands
"SIRP family members in the regulation of macrophage function" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | MOLECULAR INTERACTIONS OF IgSF GLYCOPROTEINS |
| Discussion Leader: Nicole Beauchemin, McGill University,
Montreal, Quebec, Canada |
9:00 am - 9:45 am | John E. Shively, Beckman Research Institute City of Hope, Duarte, CA "The role of CEACAM1 in lumen formation" |
9:45 am -10:30 am | Beat A. Imhof, Centre Medical Universitaire, Geneva, Switzerland
"Interactions of IgSF proteins" |
10:30 am | Coffee Break |
11:00 am - 11:45 am | Martin E. Hemler, Dana Farber Cancer Research Institute, Boston, MA
"IgSF EWI proteins regulate integrin-dependent functions" |
11:45 am - 12:30 pm | Lothar Lucka, Charité-Universitätsmedizin, Berlin, Germany
"Alteration of cell morphology and migration by CEACAM1, and its
organization in membrane microdomains" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #1 / Refreshments |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | IgSF GLYCOPROTEINS IN DEVELOPMENT AND CANCER |
| Discussion Leader: Sonia Najjar, Medical College of Ohio, Toledo, OH |
7:30 pm - 8:30 pm | Nicole Beauchemin, McGill University, Montreal QC, Canada
"The role of CEA family members in cancer progression" |
8:30 pm - 9:30 pm | Christoph Wagener, University Hospital Hamburg-Eppendorf, Hamburg,
Germany
"CEACAM1 in angiogenesis and invasive tumor growth" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | IgSF GLYCOPROTEINS IN METABOLIC DISEASES, IMMUNOREGULATION, AND CANCER |
| Discussion Leader: Sten Hammarstrom, Umea University, Umea,
Sweden |
9:00 am - 9:45 am | Sonia Najjar, Medical College of Ohio, Toledo, OH USA
"CEACAM at the crossroads between obesity and cancer" |
9:45 am - 10:30 am | Denise E. Jackson, Austin Hospital, Victoria, Australia
"Dissecting the role of PECAM-1 in immunoregulation and disease" |
10:30 am | Coffee Break |
11:00 am - 11:45 am | Clifford Stanners, McGill University, Montreal QC, Canada
"Extensive colon tumorigenesis in a transgenic mouse expressing
human tumor-like levels of CEA and CEACAM6" |
11:45 am - 12:30 pm | Robert Kammerer1, 3, Rainer Riesenberg1, Christoph Weiler1, Jens Lohrmann3, Julia Schleypen1 and Wolfgang Zimmermann1 Ludwig-Maximilians-University München, München, Germany; 3 GSF National
Research Center for the Environment and Health; 3GENOVAC GmbH,
Freiburg, Germany
"Up and down regulation of CEACAM1 in renal cell carcinoma:
A dynamic link between tumor suppression and immune escape" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session #2 / Reception |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | IgSF GLYCOPROTEINS IN INFLAMMATION AND MICROBIAL INTERACTIONS |
| Discussion Leader: Denise E. Jackson, Austin Hospital, Victoria, Australia |
7:30 pm - 8:10 pm | Terry Dermody, Vanderbilt University School of Medicine, Nashville, TN "Reovirus interactions with its receptor JAM1" |
8:10 pm - 8:50 pm | Mumtaz Virji, University of Bristol, Bristol, UK
"CEACAMs, respiratory bacteria and host-pathogen cross-talk" |
8:50 pm - 9:30 pm | Elizabeth Kornecki, State University of NY, Brooklyn, NY
"F11R, an immunoglobulin family member in platelets and endothelial cells:
role in inflammatory thrombosis" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | EVOLUTION OF IgSF GENES AND IMMUNE RECOGNITION |
| Discussion Leader: Mumtaz Virji, University of Bristol, Bristol, UK |
9:00 am - 9:45 am | Wolfgang Zimmermann, University Clinic Grosshadern, Munich, Germany "Evolution of the CEA gene family" |
9:45 am - 10:30 am | Guy M. Benian, Emory University, Atlanta, GA
"IgSF proteins in C. elegans: Roles in muscle function and development" |
10:30 am | Coffee Break |
11:00 am - 11:40 am | John P. Cannon, Robert N. Haire, Donna Eason, David Ostrov and
Gary W. Litman, University of South Florida, Tampa, Florida
"New families of diversified chordate immune-type receptors" |
11:40 am - 12:05 pm | Chittoor Swaminathan, CARB/UMBI, Rockville, Maryland
"Entropically assisted carbohydrate recognition by a natural killer
cell surface receptor, Siglec-7" |
12:05 pm - 12:30 pm | Mythily Srinivasan, Indiana University School of Dentistry, Indianapolis,
Indiana
"Novel b7-competitive antagonist peptides prevent collagen-induced
arthritis" |
12:30 pm | Lunch |
1:30 pm - 5:00 pm | Free Time |
5:00 pm - 6:00 pm | Poster Session #2 / Refreshments |
6:00 pm | Dinner |
7:30 pm - 8:00 pm | Business meeting |
8:00 pm - 9:30 pm | EXPRESSION AND DYNAMICS OF IgSF GLYCOPROTEINS |
| Discussion Leader: Terry Dermody, Vanderbilt University School of Medicine, Nashville, Tennessee |
8:00 pm - 8:30 pm | Elisabeth Raschperger, Ludwig Institute for Cancer Research, Stockholm,
Sweden
"The in vivo distribution of the Coxsackie- and Adenovirus Receptor (CAR)
in epithelial tight junctions" |
8:30 pm - 9:15 pm | Björn Öbrink, Karolinska Institute, Stockholm, Sweden
"Molecular interactions of CEACAM1 - implications for cell surface
control of signal transduction" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |