Gordon Research Conferences
Meeting Details
Search:
  GO

Microbial Toxins & Pathogenicity
Gordon Research Conference

Bacterial Pathogens: From Basics to Encounters with the Host Cell

Dates

July 10-15, 2016

Location

Waterville Valley
Waterville Valley, NH

Organizers

Chair:
Virginia L. Miller

Vice Chair:
Andrew Camilli

Meeting Description

The 2016 Gordon Research Conference (GRC) "Microbial Toxins and Pathogenicity" and its companion Gordon Research Seminar (GRS) are designed to showcase exciting, innovative basic and applied research in the infectious disease fields while promoting intensive discussion and networking between new and veteran researchers from academia, government, medicine and biotech. This biennial international conference continues to be regarded by the microbial pathogenesis community as our premier venue for intellectual exchange. To be held July 9-15 at the Waterville Valley Resort in New Hampshire, the 2016 Conference is led by Chair Virginia Miller, PhD and Vice Chair Andrew Camilli, PhD. Nine sessions will feature 31 invited speakers plus 4 selected from the GRS, chosen to integrate cutting-edge research on: bacterial toxins, virulence regulation, pathogenesis, pathogen evolution, pathogen encounters with host cells, basics of bacterial pathogens, and innate immune responses. Poster sessions will promote extended discussions between colleagues within and across disciplines and ranks. To integrate and develop the next generation of scientists in our field, the GRC will be preceded by a GRS. Together the Seminar and Conference promise to provide an exceptional forum for a diverse population of scientists to learn about cutting edge discoveries in the field, and consider and challenge the current paradigms, barriers and opportunities to advancing knowledge of molecular mechanisms of microbial infection.

New this year: To promote diversity among participants (ethnic diversity; inclusion of international participants or participants from smaller schools) travel fellowships of $500 each will be available to attend the meeting. To apply for the fellowship you must first apply and be accepted to the GRC, then apply to the meeting Chair for the fellowship (send CV and short note of how you would contribute to diversity). These applications will be due before May 15th, 2016. Awardees will be notified by May 20th, 2016.

Related Meeting

This GRC was held in conjunction with the "Microbial Toxins & Pathogenicity" Gordon Research Seminar (GRS). Refer to the associated GRS program page for more information.

Contributors

Final Meeting Program

Sunday
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Session: Microbial Toxins and Pathogenicity
Discussion Leader: Andrew Camilli (Tufts University School of Medicine, USA)
7:40 pm - 7:50 pmIntroduction by Discussion Leader
7:50 pm - 8:35 pmPascale Cossart (Pasteur Institute, France)
"Listeria monocytogenes: A Unique Model in Infection Biology"
8:35 pm - 8:50 pmDiscussion
8:50 pm - 9:05 pmAaron Whiteley (University of California, Berkeley, USA)
"Why Is the PAMP Cyclic Di-AMP Essential in Listeria monocytogenes?"
9:05 pm - 9:10 pmDiscussion
9:10 pm - 9:25 pmCara Mozola Forsberg (University of Washington, USA)
"What P. aeruginosa Traits Promote Chronic Infection of CF Airways?"
9:25 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmToxins - Action, Targeting and Structure
Discussion Leader: Joseph Barbieri (Medical College of Wisconsin, USA)
9:00 am - 9:10 amIntroduction by Discussion Leader
9:10 am - 9:35 amBorden Lacy (Vanderbilt University School of Medicine, USA)
"Structure and Function of Clostridium difficile Toxins, TcdA and TcdB"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amNeal Alto (University of Texas Southwestern Medical Center, USA)
"The Biochemistry of Immune Suppression by Bacterial Pathogens"
10:10 am - 10:20 amDiscussion
10:20 am - 10:45 amGroup Photo / Coffee Break
10:45 am - 11:10 amJorge Galan (Yale School of Medicine, USA)
"Salmonella typhi's Typhoid Toxin"
11:10 am - 11:20 amDiscussion
11:20 am - 11:45 amJimmy Ballard (University of Oklahoma Health Sciences Center, USA)
"Exploring Variant Forms of Clostridium difficile TcdB"
11:45 am - 11:55 amDiscussion
11:55 am - 12:15 pmSeema Mattoo (Purdue University, USA)
"From Bacterial Pathogens to ER Homeostasis: Fic Proteins in Cellular Signalling"
12:15 pm - 12:20 pmDiscussion
12:20 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
3:00 pm - 4:00 pmPower Hour
The GRC Power Hour is an optional informal gathering open to all meeting participants. It is designed to help address the challenges women face in science and support the professional growth of women in our communities by providing an open forum for discussion and mentoring.
Organizer: Heran Darwin (New York University School of Medicine, USA)
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmRegulation of Virulence
Discussion Leader: Peggy Cotter (University of North Carolina at Chapel Hill, USA)
7:30 pm - 7:40 pmIntroduction by Discussion Leader
7:40 pm - 8:05 pmTheresa Koehler (McGovern Medical School, University of Texas Health Science Center at Houston, USA)
"What Does the Phophoenolpyruvate Phosphotransferase System Have to Do with Bacillus anthracis Virulence?"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmVictoria Stone (University of California, Santa Cruz, USA)
"Control of Yersinia Virulence Factor Expression and Pathogenesis by the Iron Sulfur Cluster Transcription Factor IscR"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmMelanie Blokesch (École Polytechnique Fédérale de Lausanne, Switzerland)
"The Yin and Yang of Type VI Secretion Regulation in Pandemic Vibrio cholerae"
9:15 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmGeneral Discussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmPathogenesis
Discussion Leader: Beth McCormick (University of Massachusetts Medical School, USA)
9:00 am - 9:10 amIntroduction by Discussion Leader
9:10 am - 9:35 amArturo Zychlinsky (Max Planck Institute for Infection Biology, Germany)
"Antimicrobial Activity of Neutrophils"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amJoan Mecsas (Tufts University School of Medicine, USA)
"Interactions Between Yersinia and Innate Immune Cells"
10:10 am - 10:20 amDiscussion
10:20 am - 10:45 amCoffee Break
10:45 am - 11:10 amSarah Fortune (Harvard T.H. Chan School of Public Health, USA)
"Identifying Determinants of the Outcome of M. tuberculosis Infection Through Single Cell Analyses"
11:10 am - 11:20 amDiscussion
11:20 am - 11:45 amMichael Bachman (University of Michigan, USA)
"Insights into Klebsiella pneumoniae Pathogenesis from Patients and Their Animal Models"
11:45 am - 11:55 amDiscussion
11:55 am - 12:20 pmJoanne Engel (University of California, San Francisco, USA)
"Defining the Chlamydia Inclusion Membrane Protein-Host Protein Interactome"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmPathogen Evolution
Discussion Leader: William Goldman (University of North Carolina at Chapel Hill, USA)
7:30 pm - 7:40 pmIntroduction by Discussion Leader
7:40 pm - 8:05 pmNels Elde (University of Utah, USA)
"Experimental Evolution of Pathogen Populations"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmKim Seed (University of California, Berkeley, USA)
"Fighting with Phages: How Epidemic Vibrio cholerae Defends Against Viral Attack"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmWyndham Lathem (Feinberg School of Medicine, Northwestern University, USA)
"From Mild to Murderous: How Yersinia pestis Evolved into an Efficient Killer"
9:15 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmGeneral Discussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmBasics of Bacterial Pathogens
Discussion Leader: Heran Darwin (New York University School of Medicine, USA)
9:00 am - 9:10 amIntroduction by Discussion Leader
9:10 am - 9:35 amMiriam Braunstein (University of North Carolina at Chapel Hill, USA)
"Unraveling the Role of the SecA2 Pathway in Mycobacterium tuberculosis in Macrophages"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amMichael Federle (University of Illinois at Chicago, USA)
"Social Appearances: Quorum Sensing Control of the Cell Envelope of Streptococcus pyogenes"
10:10 am - 10:20 amDiscussion
10:20 am - 10:45 amCoffee Break
10:45 am - 11:10 amNina Salama (Fred Hutchinson Cancer Research Center, USA)
"Bacterial Adaptations for Life in the Stomach"
11:10 am - 11:20 amDiscussion
11:20 am - 11:45 amAndrew Darwin (New York University School of Medicine, USA)
"Pushing the Envelope in Bacterial Pathogenesis"
11:45 am - 11:55 amDiscussion
11:55 am - 12:20 pmVincent Lee (University of Maryland, College Park, USA)
"Discovery of Signaling Nucleotide Receptors and Their Inhibitors"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmClose Encounters with the Host Cell
Discussion Leader: Mary O'Riordan (University of Michigan Medical School, USA)
7:30 pm - 7:40 pmIntroduction by Discussion Leader
7:40 pm - 8:05 pmBarbara Kazmierczak (Yale University, USA)
"Phenotypic Heterogeneity in Pseudomonas Pathogenesis"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:40 pmRaphael Valdivia (Duke University Medical Center, USA)
"Mechanisms of Cell Survival in Chlamydia Infected Cells"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmAlison Criss (University of Virginia, USA)
"Flirting with Disaster: How Neisseria gonorrhoeae Survives Encounters with Neutrophils"
9:15 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmGeneral Discussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmInnate Immune Responses and Pathogenesis
Discussion Leader: Manuela Raffatellu (University of California, Irvine, USA)
9:00 am - 9:10 amIntroduction by Discussion Leader
9:10 am - 9:35 amJyothi Rengarajan (Emory University, USA)
"Mycobacterium tuberculosis Modulation of Innate-Adaptive Crosstalk"
9:35 am - 9:45 amDiscussion
9:45 am - 10:10 amDavid Underhill (Cedars-Sinai Medical Center, USA)
"Innate Immune Recognition of Bacterial Cell Walls"
10:10 am - 10:20 amDiscussion
10:20 am - 10:45 amCoffee Break
10:45 am - 11:10 amJorge Henao-Mejia (University of Pennsylvania, USA)
"Regulation of Immune Host Defense by Novel Long Non-Coding RNAs"
11:10 am - 11:20 amDiscussion
11:20 am - 11:45 amKen Cadwell (New York University School of Medicine, USA)
"Autophagy and Enteric Bacterial Infections"
11:45 am - 11:55 amDiscussion
11:55 am - 12:20 pmSunny Shin (University of Pennsylvania, USA)
"Overcoming Bacterial-Encoded Virulence Activities to Initiate Innate Immune Defense"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmKeynote Session: Perspectives on the Future of Host-Pathogen Interaction Research
Discussion Leader: Karen Ottemann (University of California, Santa Cruz, USA)
5:30 pm - 5:40 pmIntroduction by Discussion Leader
5:40 pm - 6:25 pmEric Skaar (Vanderbilt University, USA)
"The Intersection of Nutrition and Infection at the Host-Pathogen Interface"
6:25 pm - 6:40 pmDiscussion
6:40 pm - 6:55 pmLillian Juttukonda (Vanderbilt University, USA)
"Dietary Manganese and the Host Protein Calprotectin Promote Staphylococcal Infection of the Hear"
6:55 pm - 7:00 pmDiscussion
7:00 pm - 7:15 pmDamien Keogh (SCELSE, Nanyang Technological University, Singapore)
"Enterococcus faecalis Powers Biofilm Formation Through Extracellular Electron Transfer of Iron"
7:15 pm - 7:20 pmDiscussion
7:20 pm - 7:30 pmGeneral Discussion
8:00 pmDinner
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible in part by 1 R13 AI124475-01 from the National Institute of Allergy and Infectious Diseases. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter