Gordon Research Conferences
Meeting Details
Search:
  GO

Human Genetics & Genomics
Gordon Research Conference

The Emergent Utility Human Genomics in Clinics, in Populations, and in Homes

Dates

July 9-14, 2017

Location

Stoweflake Conference Center
Stowe, VT Site Information

Organizers

Chair:
Carlos Bustamante

Vice Chair:
Nicholas Katsanis

Application Deadline

Applications for this meeting must be submitted by June 11, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

When our conference began in 1995, Human Genetics and Genomics was largely a small community of investigators positionally cloning genes and mutations underlying Mendelian disorders and/or studying evolutionary patterns using small numbers of genes and markers. The Human Genome project was years away from completion and everyone doing important work in the field fit into a 500 person auditorium. Today, human genetics and genomics has become central to a myriad of fields. Drug discovery is being driven by the hunt for so-called protective loss of function mutations. Direct-to-consumer companies (and similar efforts) give people the tools to retrace their ancestry, learn carrier status for a host of Mendelian disorders, estimate risk for complex disease, and connect with long lost relatives (including biological parents or offspring). Major medical centers (and now even community hospitals) are launching ambitious efforts to genotype (or sequence) their patient population. In short, the future is here. The purpose of our conference is to bring together thought leaders from academia, industry, government, and the non-profit sector, along with students, post-docs, and junior investigators who are building much of this world. Be prepared for spirited debate, and to challenge what you think you know about human genetics and genomics and what it all means for us as investigators, patients, and people.

Related Meeting

This GRC will be held in conjunction with the "Human Genetics & Genomics" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Meeting Program

Sunday
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmChallenges and Opportunities in Medical Genomics
Discussion Leader: Nicholas Katsanis (Duke University, USA)
7:40 pm - 7:45 pmOpening Remarks
7:45 pm - 8:10 pmMichael Talkowski (Massachusetts General Hospital, USA)
"Sequence-Resolution Association Studies in Autism: Insights into Genetic Architecture and Challenges to Interpretation"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmCharles Rotimi (National Human Genome Research Institute, NIH, USA)
"Sustaining the Growing Genomic Success Stories to Ensure Tomorrow’s Medicine for Africans"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmCisca Wijmenga (University Medical Center Groningen, The Netherlands)
"Our Second Genome: A Vital Organ Integrating Host Genome and Host Environment"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmThe Human Genome: Resource, Commodity, or Both?
Discussion Leader: Gary Churchill (The Jackson Laboratory, USA)
9:00 am - 9:30 amLeslie Biesecker (National Human Genome Research Institute, USA)
"A Mutation Is Not a Diagnosis: An Integrated Bayesian Approach to Clinical Genomics"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amChristine Seidman (Harvard Medical School, USA)
"Human Genetics: Getting to the Heart of the Matter"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 amCoffee Break
10:50 am - 11:20 amRichard Gibbs (Baylor College of Medicine, USA)
"Precision Medicine and Oligogenics"
11:20 am - 11:30 amDiscussion
11:30 am - 11:45 amShort Talk Selected from Poster Abstracts
11:45 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmOur Genomes and How They've Evolved
Discussion Leader: Sali Farhan (Massachusetts General Hospital / Broad Institute of MIT and Harvard, USA)
7:30 pm - 8:00 pmEvan Eichler (University of Washington / Howard Hughes Medical Institute, USA)
"Human Evolution by Segmental Duplication"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmEimear Kenny (Icahn School of Medicine at Mount Sinai, USA)
"Embracing Diversity for Improving Genomic Medicine"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmElaine Ostrander (National Human Genome Research Institute, NIH, USA)
"People and Their Dogs: The Tales They Tell"
9:20 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmThe "Other" Genomes: Microbiomes, Epigenomes, and Other Uncomfortable Truths
Discussion Leader: Elaine Ostrander (National Human Genome Research Institute, NIH, USA)
9:00 am - 9:30 amAmi Bhatt (Stanford University, USA)
"Metagenomics and Medicine (Investigating the Role of Microbial Genes and Gene Products in Human Health)"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amSharon Plon (Baylor College of Medicine, USA)
"The Expanding Genomic Landscape of Pediatric Cancer"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 amCoffee Break
10:50 am - 11:20 amDavid Page (Whitehead Institute for Biomedical Research, USA)
"Sex and Disease: Do Males and Females Read Their Genomes Differently?"
11:20 am - 11:30 amDiscussion
11:30 am - 11:45 amShort Talk Selected from Poster Abstracts
11:45 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmBig Data, Precision Medicine, and the Transition from the Clinic to the Laptop
Discussion Leader: Eimear Kenny (Icahn School of Medicine at Mount Sinai, USA)
7:30 pm - 8:00 pmNancy Cox (Vanderbilt University, USA)
"Using Biobanks for Novel Discovery and Translation"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmTuuli Lappalainen (New York Genome Center, USA)
"Functional Variation in the Human Genome: Lessons from the Transcriptome"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmGeoff Benton (23andMe, USA)
"Predicting BMI: Polygenic Models and Beyond"
9:20 pm - 9:30 pmDiscussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmFunctional Genomics: Progress and Questions of Scaling
Discussion Leader: Michael Talkowski (Massachusetts General Hospital, USA)
9:00 am - 9:30 amGary Churchill (The Jackson Laboratory, USA)
"Post-Translational Mechanisms Buffer Protein Abundance Against Transcriptional Variation"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amEmmanouil Dermitzakis (University of Geneva, Switzerland)
"Contribution of Non-Coding DNA to Disease Susceptibility and Cancer"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 amCoffee Break
10:50 am - 11:20 amPamela Sklar (Icahn School of Medicine at Mount Sinai, USA)
"Polymorphously Polygenic: The Story of the Genome in Schizophrenia"
11:20 am - 11:30 amDiscussion
11:30 am - 11:45 amShort Talk Selected from Poster Abstracts
11:45 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmLooking at the Hope and the Hype in Genomic Therapeutics
Discussion Leader: Sekar Kathiresan (Massachusetts General Hospital, USA)
7:30 pm - 8:00 pmEuan Ashley (Stanford University, USA)
"Dissecting the Molecular Genetics of Inherited Cardiovascular Disease"
8:00 pm - 8:10 pmDiscussion
8:10 pm - 8:40 pmSusan Slaugenhaupt (Harvard University, USA)
"Splice Here, Splice There, Splice Everywhere"
8:40 pm - 8:50 pmDiscussion
8:50 pm - 9:20 pmTamar Grossman (Ionis Pharmaceuticals, USA)
"Antisense Oligonucleotide Based Therapy for Genetic Diseases"
9:20 pm - 9:30 pmDiscussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIntegrating Genetics into the Clinic
Discussion Leader: Sharon Plon (Baylor College of Medicine, USA)
9:00 am - 9:30 amSekar Kathiresan (Massachusetts General Hospital, USA)
"Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease"
9:30 am - 9:40 amDiscussion
9:40 am - 10:10 amJames Lupski (Baylor College of Medicine, USA)
"Genomics of Disease"
10:10 am - 10:20 amDiscussion
10:20 am - 10:50 amCoffee Break
10:50 am - 11:20 amTaylor Sittler (Color Genomics, USA)
"Low-Cost Hereditary Testing Is Enabling Research"
11:20 am - 11:30 amDiscussion
11:30 am - 11:45 amShort Talk Selected from Poster Abstracts
11:45 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmHuman Genetics and Genomics in 10 Years
Discussion Leader: Carlos Bustamante (Stanford University, USA)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 8:05 pmDavid Altshuler (Vertex Pharmaceuticals, USA)
"Humanizing Drug Recovery"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:45 pmDavid Goldstein (Columbia University, USA)
"Epilepsy Precision Medicine"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:15 pmGeneral Discussion
9:15 pm - 9:30 pmClosing Remarks
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter