Applications for this meeting must be submitted by June 25, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.
The Gordon Research Conference (GRC) series on "Cell Biology of Metals" provides a truly outstanding forum for scientific exchanges, presentations and discussions in the emerging field of metals in biology, focusing on the acquisition, distribution, sensing and utilization of metals in proteins, cells and systems from bacteria to humans. This conference has now become a cornerstone of the field and is unique in attacking broad research questions such as how metal cofactors are assembled to how metal ions play roles in metabolic and infectious diseases. The 2017 Cell Biology of Metals GRC will be held on July 23-28 at Mount Snow Resort in West Dover, VT. The program is organized around the theme of "Mechanisms from Microbes to Humans". Session topics include metals in enzyme function, metalloenzyme structures, metal homeostasis, metal sensing and dynamics, metalloprotein biogenesis and signaling, metals in host-pathogen interactions and metals in physiology and disease. The conference will be comprised of keynote presentations, research and poster talks, poster discussions, and informal scientific discussions. This meeting will bring together an outstanding and diverse cadre of molecular and structural biologists, biochemists, geneticists, cell biologists, physiologists and clinicians to interact and brainstorm on new discoveries, ideas and directions in basic and applied research on the cell biology of metals. Given the increase in the number of metabolic and infectious diseases linked to changes in cellular metal homeostasis, this meeting fills a critical niche for investigating the underlying mechanism(s) of these disorders and for brainstorming approaches for novel diagnostics, prognostics, and therapeutics.
This GRC will be held in conjunction with the "Cell Biology of Metals" Gordon Research Seminar (GRS)
. Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page
for more information.
The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 23, 2017. Please check back for updates.
Keynote Session: Metal Homeostasis in Development and Disease
(Roland Lill / Svetlana Lutsenko / Ralf Mendel)
Metals in Enzyme Function
(David Giedroc / Nigel Robinson / Vishal Gohil / Daniel Kosman)
Structural Basis of Metalloprotein Function
(Amy Rosenzweig / Amie Boal / Hans Christensen / Richard Ortega)
(David Eide / Mitchell Knutson / Ute Kramer / Somshuvra Mukhopadhyay / Jared Rutter)
Metal Sensing and Dynamics
(Amy Palmer / Ankona Datta / James Imlay / Patricia Kiley / Amit Reddi)
Metalloprotein Biogenesis and Signaling
(Frederic Barras / Donita Brady / Simon Labbe / Amanda Bird / Silke Leimkuhler)
Metals in Host-Pathogen Interactions
(Elizabeth Nolan / Pascal Arnoux / Christopher McDevitt / Dennis Thiele / Alejandro Vila)
Metals in Physiology and Disease
(Martina Muckenthaler / Marla Berry / Elizabeth Leibold / Stefano Rivella)
Keynote Session: Metal Homeostasis from Worms to Mammals
(Michael Petris / Vadim Gladyshev / Iqbal Hamza)
Funding for this conference was made possible (in part) by 1 R13 DK113725-01 from NIDDK. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. government.