SATURDAY |
1:00 pm - 5:00 pm | Arrival and Check-in |
3:30 pm - 3:45 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
3:45 pm - 4:30 pm | Apoptotis and beyond: lessons from the cell death-autophagy-inflammation axis |
| Discussion Leader: Markus Hoffmann (University of Erlangen-Nuremberg, Germany) |
3:45 pm - 4:15 pm | Douglas Green (St. Jude Children's Research Hospital, USA)
"LC3-Associated Phagocytosis: at the intersection of autophagy, innate immunity, and degenerative processes"
|
4:15 pm - 4:30 pm | Discussion |
4:30 pm - 6:00 pm | Poster Session I |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | The phagocyte and the prey: a dangerous rendezvous |
| Discussion Leader: Zsusa Szondy (University of Debrecen-MHSC, Hungary) |
7:30 pm - 7:50 pm | Alexandra McCubbrey (University of Michigan, USA)
"Novel role for miR-34a in controlling apoptotic cell clearance in the lung and brain"
|
7:50 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Mao Yingyu (Fordham University, USA)
"RhoA and Rac1 GTPases contribute independently to F-actin regulation during clearance phagocytosis by retinal pigment epithelial cells"
|
8:20 pm - 8:30 pm | Discussion |
8:30 pm - 8:50 pm | Christian Maueröder (University of Erlangen-Nuremberg, Germany)
"Immune response against dying cells in vivo"
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8:50 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Helena Paidassi (MGH/Harvard Medical School, USA)
"How apoptotic cells spice the inflammation down"
|
9:20 pm - 9:30 pm | Discussion |
SUNDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:00 am | How not to lose control on cell death |
| Discussion Leader: Christopher Gregory (MRC-Centre for Inflammation Research, UK) |
9:00 am - 9:20 am | Luis Munoz (University of Erlangen-Nuremberg, Germany)
"Sialylation of anti-histone IgG autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells"
|
9:20 am - 9:30 am | Discussion |
9:30 am - 9:50 am | Anna Zagorska (The Salk Institute, USA)
"Axl Tyrosine Kinase is a Phagocytic Receptor for Apoptotic Cells During Inflammation"
|
9:50 am - 10:00 am | Discussion |
10:00 am - 10:20 am | Edina Keresztesi (University of Debrecen-MHSC, Hungary)
"Adenosine as a mediator of the anti-inflammatory effect of the apoptotic cell uptake"
|
10:20 am - 10:30 am | Discussion |
10:30 am - 10:50 am | Kyle Phua (Duke University, USA)
"Induction of Anti-Tumor Immunity With RNA loaded Apoptotic Cell and Gene Dual Therapy"
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10:50 am - 11:00 am | Discussion |
11:00 am - 12:30 pm | Poster Session II |
| Coffee will be served in the poster area from 11:00 am - 11:30 am |
12:30 pm | Lunch |
1:30 pm - 2:30 pm | Updates on cell adhesion, migration and extrusion |
| Discussion Leader: Gerhard Kroenke (University of Erlangen-Nuremberg, Germany) |
1:30 pm - 1:50 pm | Anne-Marie Pret (Centre national de la Recherche Scientifique, France)
"JAK/STAT signaling controls loss of cell polarity and adhesion during apoptotic elimination of supernumerary polar cells from the Drosophila follicular epithelium"
|
1:50 pm - 2:00 pm | Discussion |
2:00 pm - 2:20 pm | Iwan Evans (University of Bath, UK)
"SCAR/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila"
|
2:20 pm - 2:30 pm | Discussion |
2:30 pm - 3:00 pm | Evaluation Period |
| Fill out GRS Evaluation Forms |
3:00 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |