Gordon Research Conferences
Meeting Details

Cellular & Molecular Mechanisms of Toxicity
Gordon Research Conference

Advanced Investigation in Mechanistic Toxicology


August 13-18, 2017


Proctor Academy
Andover, NH Site Information


Yanan Tian

Vice Chair:
John H. Richburg

Application Deadline

Applications for this meeting must be submitted by July 16, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The Gordon Research Conference (GRC) on Cellular and Molecular Mechanisms of Toxicity is the premier forum for showcasing the latest, most innovative advances in mechanistic toxicological research. For the 2017 conference, the organizers have assembled a group of world-leading experts working on areas of investigation that are highly relevant to environmental, industrial, and pharmaceutical toxicology, with the goal of incorporating the molecular basis of disease into risk management and decision making. Emerging technologies in mechanistic toxicology and model and systems biology approaches to assessing risk to human disease will be highlighted along with the microbiome, epigenomics including noncoding RNA, application of new technology such as CRISPR/Cas9, and transgenerational mechanisms of toxicology. For the third consecutive time, a Gordon Research Seminar (GRS) on Cellular and Molecular Mechanisms of Toxicity will precede the conference. The GRS is organized and run by graduate students and fellows entirely and provides an expanded opportunity for trainees and young scientists to be exposed to cutting-edge science and to network with their future colleagues in the field. The poster session of the GRC is an essential element to the success of conference. Trainees and scientists at any level will have the opportunity to present their latest, groundbreaking work in poster format under an informal atmosphere that fosters relaxed dialog, networking and idea sharing. A special selection committee will select some abstracts/posters for short oral talks. These "late-breaking" oral sessions provide increased participation to trainees and young scientists to share their work with an audience of experts. This is a tremendous opportunity for the young talent to receive feedback from well-established leaders in the field. Another key to the success of the GRC is the social interaction of participants at meal times and during social activities in afternoon breaks. These interactions have led to long-lasting scientific collaborations and the lining up of trainees with laboratories for further education. We look forward to seeing you at the Gordon Research Conference on Cellular and Molecular Mechanisms of Toxicology in 2017!

Related Meeting

This GRC will be held in conjunction with the "Cellular & Molecular Mechanisms of Toxicity" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.


Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by April 13, 2017. Please check back for updates.

  • Keynote Session: New Science and New Horizons in Mechanistic Toxicology
    (Charlene McQueen / John Rinn / Kenneth Ramos)
  • Xenobiotic Receptors and Their Novel Functions
    (Michael Gallo / Gary Perdew / Masahiko Negishi / Wen Xie)
  • Genetic and Epigenetic Mechanisms of Toxicology
    (Shaun McCullough, Patrick Allard / Brian Strahl / Kari Nadeau / Richard Woychik)
  • Noncoding RNA and Their Roles in Regulating Toxic Responses
    (Frederick Tyson / Dana Dolinoy / Chuan He / Chengfeng Yang)
  • Humanized Models: Where Are We Now?
    (Heather Wallace / Michael Brehm / Matthew Wright)
  • Tick Tock Goes the Clock: Circadian Rhythm of Gut Microbiota Influences Host Metabolic and Drug Functions
    (Tamara Tal / Lora Hooper / Vanessa Leone / Helmut Zarbl)
  • Non-Animal Methods in Toxicology: Novel Mechanisms and New Opportunities
    (Ruth Roberts / Rebecca Clewell / John Colbourne / Caroline Ring)
  • System Biological Approaches to Assessing Xenobiotic Responses
    (Ronald Hines, Rhiannon Hardwick / Ting Wang / Stephen Edwards / Craig Rowlands)
  • Keynote Session: Genetic and Epigenetic Mechanisms of Toxicity
    (Michael Holsapple / Quan Lu / Cheryl Walker)
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