Applications for this meeting must be submitted by December 21, 2014. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.
The Immunology of Fungal Infections Gordon Research Conference will be held in conjunction with the Immunology of Fungal Infections Gordon Research Seminar
. Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Please refer to the Immunology of Fungal Infections GRS web page for more information.
Fungal diseases are a major cause of morbidity and mortality in healthy and immune-compromised individuals. A finely tuned immune response is critical, since either insufficient or exaggerated responses undermine the host's ability to eradicate fungal infection. Major strides have been made in understanding the innate and adaptive components underlying protective and non-protective mechanisms of immunity. Newfound recognition of the immunological roles of nutrient limitation, abiotic stress, non-hematopoietic cells, co-evolution of fungal-host interactions, and trafficking of intracellular cargo in phagocytes has lead to novel insights about mechanisms that restrain fungi or that cause immunopathology. Recent work demonstrates that the host microbiota shapes the immune system and modulate its interactions with fungi. These discoveries allow a better understanding of the factors that regulate disease susceptibility, including genetic variation of immune-response genes, and provide a basis for strategies involving immunotherapy and vaccination. This conference will bring together the world's leading researchers investigating antifungal immunity, in a setting ideal for promoting cross-disciplinary discussions and collaborations. This will provide a compelling and informative meeting covering the latest advances in the field and the most pressing issues to be tackled.
A list of preliminary session topics and speakers is displayed below (discussion leaders are noted in italics). The detailed program is currently being developed by the Conference Chair and will be available by September 18, 2014. Please check back for updates.
Keynote Session: Immunogenetics of Fungal Disease
(Jean-Paul Latge / Steven Holland / Anne Puel / Keynote: Luigina Romani)
Components of Innate Immunity to Fungi
(Sarah Gaffen / Salome Leibundgut-Landmann / Amariliz Rivera / Frank Van De Veerdonk / Tobias Hohl / Christopher Mody / Jessica Quintin)
Innate Sensing and Signaling: PRRs and Beyond
(Karl Kuchler / Gordon Brown / Teunis Geijtenbeek / Jurgen Rhuland / Sarah Gaffen)
Structures and Signals that Impact Fungal Immunity
(Mairi Noverr / Sho Yamasaki / Neil Gow / Jean-Paul Latge / Robert Cramer / Marcel Wuethrich / Karl Kuchler / Robert Wheeler)
Adaptive and Maladaptive Immunity to Fungi
(Gordon Brown / Stuart Levitz / Daniel Kaplan / Liise-Anne Pirofski)
Mycobiome, Mammalian Surfaces, and Non-Hematopoietic Lining Cells
(Scott Filler / David Underhill / Mairi Noverr / Suzanne Noble / Julian Naglik / Teresa Zelante / Terry Wright)
Host-Fungal Pathogen Interactions: Systems Biology and Beyond
(Luigina Romani / Duccio Cavalieri / Marcio Rodrigues / Norman Pavelka / Louise Rollins-Smith)
(Stuart Levitz / Jatin Vyas / Robin May / Anita Sil / Thirumala-Devi Kanneganti)
Harnessing Immunity to Fungi in the Clinic
(Suzanne Noble / Agostinho Carvalho / Scott Filler / Michail Lionakis / Jay Kolls)