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Drinking Water Disinfection By-Products
Gordon Research Conference

Disinfection 2100: Linking Engineering, Chemistry, Toxicology and Epidemiology to Reduce Exposure to Toxicity Drivers While Curtailing Pathogens

Dates

July 30 - August 4, 2017

Location

Mount Holyoke College
South Hadley, MA Site Information

Organizers

Chair:
William A. Mitch

Vice Chair:
Xingfang Li

Application Deadline

Applications for this meeting must be submitted by July 2, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 meeting has two main goals. The first goal is to broaden the scope beyond DBP formation within conventional drinking water plants. Disinfection represents a balance between controlling the acute risk associated with pathogens and the chronic risk linked to DBPs. The first two sessions will address this balance directly. The first session will evaluate disinfectant reactions with pathogens, recognizing that the biomolecular transformations responsible for pathogen kill are DBPs. The second session will cover tradeoffs between microbial growth and DBPs within distribution systems, the least evaluated sector of drinking water systems. The sixth section will focus on DBPs in wastewater recycling, particularly which DBPs contribute most to toxicity and how to control them. The conference will also include new arenas for DBPs, including a talk by Clorox on disinfectant design for consumer applications, and the formation of DBPs during food processing.

The second goal is to move towards a solution to the DBP problem. A major strength of this conference is that it brings together engineers, chemists, toxicologists, epidemiologists and regulators, the key players for addressing this problem. Previous conferences have concluded that there is no feasible way to control pathogens without producing DBPs, so the challenge is to achieve the best balance that minimizes exposure to the DBPs driving risk. Sessions will link chemistry and toxicology to identify these toxicity drivers. Session 8 will feature discussions among chemists, exposure experts and epidemiologists about how the ideal epidemiology study should be designed to provide the evidence to link exposure to human health risks. Session 9 will conclude with presentations and a discussion regarding how to design water treatment systems that minimize toxicity drivers, including a presentation from a Dutch utility on how to avoid the use of disinfectants in drinking water distribution systems.

Related Meeting

This GRC will be held in conjunction with the "Drinking Water Disinfection By-Products" Gordon Research Seminar (GRS). Those interested in attending both meetings must submit an application for the GRS in addition to an application for the GRC. Refer to the associated GRS program page for more information.

Contributors

Meeting Program

Sunday
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmDisinfectants vs. Microorganisms: Biomolecule Transformation Products Are DBPs
Discussion Leader: Krista Wigginton (University of Michigan, USA)
7:40 pm - 7:45 pmOpening Remarks
7:45 pm - 7:50 pmIntroduction by Discussion Leader
7:50 pm - 8:30 pmTamar Kohn (Ecole Polytechnique Federale de Lausanne, Switzerland)
"How Do Disinfectants Kill Pathogens?"
8:30 pm - 8:45 pmDiscussion
8:45 pm - 9:15 pmJulie Timberman (Clorox Corporation, USA)
"Bringing a Household Disinfecting Product to Market"
9:15 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmMicroorganisms vs. DBPs in Distribution Systems - The Final Frontier
Discussion Leader: Benito Marinas (University of Illinois, USA)
9:00 am - 9:05 amIntroduction by Discussion Leader
9:05 am - 9:45 amWen-Tso Liu (University of Illinois at Urbana-Champaign, USA)
"Drinking Water Microbiome in Distribution Systems"
9:45 am - 10:00 amDiscussion
10:00 am - 10:30 amCoffee Break
10:30 am - 11:10 amGerald Speitel (University of Texas at Austin, USA)
"DBPs and Biofilm Interactions in Distribution Systems"
11:10 am - 11:30 amDiscussion
11:30 am - 12:10 pmMark LeChevallier (American Water Company, USA)
"Minimizing Microorganisms and DBPs in Distribution Systems"
12:10 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmMerging Chemistry and Toxicology
Discussion Leader: Guibin Jiang (Chinese Academy of Sciences, China)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 8:05 pmXiangru Zhang (Hong Kong University of Science and Technology, Hong Kong SAR China)
"TOX Evolution from High Molecular Weight DBPs to Aromatics to Aliphatics"
8:05 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmXingfang Li (University of Alberta, Canada)
"Identification of New DBPs of Health Relevance: Analytical and Toxicological Studies"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmHailin Wang (Chinese Academy of Sciences, China)
"Analysis of DNA Methylation and Related Oxidation Products for Testing DBP Epigenotoxicity"
9:20 pm - 9:30 pmDiscussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmFrontiers in DBP Chemistry and Engineering
Discussion Leader: Teng Zeng (Syracuse University, USA)
9:00 am - 9:05 amIntroduction by Discussion Leader
9:05 am - 9:45 amRaymond Hozalski (University of Minnesota, USA)
"Remote Sensing for Source Water Characterization"
9:45 am - 10:00 amDiscussion
10:00 am - 10:30 amCoffee Break
10:30 am - 11:00 amMichael Gonsior (University of Maryland Center for Environmental Science, USA)
"What Are High Molecular Weight Disinfection By-Products? New Insights from Non-Targeted Ultrahigh Resolution Mass Spectrometry"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amChing-Hua Huang (Georgia Institute of Technology, USA)
"F-DBPs - DBPs from Food Processing"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmChao Chen (Tsinghua University, China)
"Nitrosamine Precursor Characterization, Tracing and Control: Some New Insights by the Polarity Rapid Assessment Method (PRAM)"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmLinking Toxicology and Exposure Assessment: Which DBPs Are the Toxicity Drivers in Drinking Waters?
Discussion Leader: Jane Simmons (U.S. Environmental Protection Agency, USA)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 8:15 pmMichael Plewa (University of Illinois at Urbana-Champaign, USA)
"Toxicity Forcing Agents for Conventional Drinking Waters"
8:15 pm - 8:30 pmDiscussion
8:30 pm - 9:10 pmWeidong Qu (Fudan University, China)
"Exposure Assessment of DBPs in China and Potential Adverse Effects"
9:10 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmGeneral Discussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmWastewater Recycling and DBPs: Which DBPs Matter and How Can We Control Them?
Discussion Leader: Paul Westerhoff (Arizona State University, USA)
9:00 am - 9:05 amIntroduction by Discussion Leader
9:05 am - 9:45 amChristiane Hoppe-Jones (University of Arizona, USA)
"Forcing Agents for Potable Reuse - What Really Matters?"
9:45 am - 10:00 amDiscussion
10:00 am - 10:30 amCoffee Break
10:30 am - 11:00 amUrs Von Gunten (Swiss Federal Institute of Aquatic Science and Technology (EAWAG), Switzerland)
"O3/BAC as a Treatment Option for Potable Reuse Trains"
11:00 am - 11:10 amDiscussion
11:10 am - 11:40 amJurg Keller (University of Queensland, Australia)
"Intersection of Potable Reuse Treatment Objectives and DBPs"
11:40 am - 11:50 amDiscussion
11:50 am - 12:20 pmChii Shang (The Hong Kong University of Science and Technology, Hong Kong SAR China)
"UV/Chlorine Process - Degradation of CECs vs. Formation of DBPs"
12:20 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmPromises and Pitfalls of High Throughput Toxicological Bioassays
Discussion Leader: Michael Plewa (University of Illinois at Urbana-Champaign, USA)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 8:15 pmDaniel Stalter (Swiss Federal Institute of Aquatic Science and Technology (EAWAG), Switzerland)
"The Case for High Throughput"
8:15 pm - 8:30 pmDiscussion
8:30 pm - 9:10 pmMatias Attene Ramos (George Washington University, USA)
"Cautions for High Throughput"
9:10 pm - 9:25 pmDiscussion
9:25 pm - 9:30 pmGeneral Discussion
Thursday
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
9:00 am - 12:30 pmDesigning the Ideal Epidemiology Study of the Future
Discussion Leader: Michael Wright (National Center for Environmental Assessment, U.S. Environmental Protection Agency, USA)
9:00 am - 9:05 amIntroduction by Discussion Leader
9:05 am - 9:15 amShort Talk Selected from Poster Abstracts
9:15 am - 9:20 amDiscussion
9:20 am - 9:50 amKarin van Veldhoven (Imperial College London, United Kingdom)
"How to Introduce Omics in Molecular Epidemiology Studies on DBPs"
9:50 am - 10:00 amDiscussion
10:00 am - 10:30 amCoffee Break
10:30 am - 10:55 amStuart Krasner (Metropolitan Water District of Southern California, USA)
"What's Feasible to Measure - Can Correlations Be Made?"
10:55 am - 11:05 amDiscussion
11:05 am - 11:30 amJohn Nuckols (Colorado State University, USA)
"How Can We Improve DBP Exposure Assessment?"
11:30 am - 11:40 amDiscussion
11:40 am - 12:05 pmManolis Kogevinas (Centre for Research in Environmental Epidemiology, Spain)
"Constraints for Conducting Epidemiology Studies"
12:05 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmDisinfection Systems of the Future: How Can We Minimize Toxicity Drivers?
Discussion Leader: Susan Richardson (University of South Carolina, USA)
7:30 pm - 7:35 pmIntroduction by Discussion Leader
7:35 pm - 8:15 pmBram Martijn (PWN Technologies, The Netherlands)
"How to Run a Disinfectant-Free Distribution System"
8:15 pm - 8:30 pmDiscussion
8:30 pm - 9:00 pmStig Regli (U.S. Environmental Protection Agency, USA)
"New Regulatory Approaches to Minimizing DBP Toxicity Drivers"
9:00 pm - 9:10 pmDiscussion
9:10 pm - 9:30 pmGeneral Discussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
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