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Genome Architecture in Cell Fate & Disease
Gordon Research Conference

Defining Structure and Function of the Nucleus

Dates

July 2-7, 2017

Location

The Hong Kong University of Science and Technology
Hong Kong, China Site Information

Organizers

Chair:
Wange Lu

Vice Chairs:
David M. Gilbert & Yijun Ruan

Hong Kong Advisory Board:
Tony F. Chan, Kathryn Song Eng Cheah, Fanny M.C. Cheung, Arthur B. Ellis, Barry Halliwell, Nancy Ip, Jian Lu, Peter Mathieson, Alfonso Ngan, Paul Tam, Benjamin Wah, Henry Wong, Vivian Wing-Wah Yam, Kenneth Young & Albert Cheung-Hoi Yu More Information

Application Deadline

Applications for this meeting must be submitted by June 4, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

Accumulating evidence suggest that genomes are organized non-randomly into complex 3D configurations that vary according to cell type, stage of development, differentiation and disease status. The principles, which guide higher order organization, the mechanisms responsible for establishment, maintenance and alterations of higher order genome, and the functional consequences of aberrant genome and nuclear organization have become areas of intense interest. The higher-order spatial and temporal organization of genomes in the cell nucleus is rapidly emerging as a driver of biological function in differentiation, development and disease and the incorporation of information on higher order genome organization add an additional level of complexity in our understanding of genome regulation. These studies bring together several cutting edge fields including genomics, epigenetics, big data analysis, imaging and clinical cell and molecular biology. The 2017 conference on Genome Architecture in Cell Fate and Disease aims to foster a new community that is devoted to the understanding of nuclear architecture in cell fate determination, development, disease modeling, stem cell biology and regenerative medicine. Particularly emphasis will be placed on genome organization, epigenetic remodeling, chromatin folding, structural elements of the nucleus and its relevance in gene transcription. Another angle is to promote cutting edge tools that allow us to visualize the nucleus. We seek to unify and integrate chemical, biological, physiological as well as physical parameters into a coherent picture of the nucleus, especially the human one.

Contributors

Preliminary Program

The topics and speakers for the conference sessions are displayed below (italics denote discussion leaders). The Conference Chair is currently developing their detailed program, which will include the complete meeting schedule, as well as the talk titles for all speakers. The detailed program will be available by March 2, 2017. Please check back for updates.

  • Structure of the Nucleus
    (Wange Lu / Thomas Misteli)
  • 3D Nuclear Structure and Human Diseases
    (Peter Fraser / Rafael Casellas / Martin Hetzer)
  • Epigenetic Pathways
    (Laurie Boyer / Woojin An)
  • Cancer Epigenome
    (Thomas Misteli / Bing Ren)
  • Chromatin Structure and Stem Cells
    (Joanna Wysocka / Laurie Boyer / Duanqing Pei)
  • Chromatin Structure and Development
    (Duanqing Pei / Victor Corces / Qiang Wu)
  • Epigenome, Chromatin Structure and Gene Transcription
    (Yijun Ruan / Joanna Wysocka / Wouter De Laat)
  • Non-Coding RNA and Chromatin Structure
    (Rafael Casellas / Mitch Guttman / Peter Fraser)
  • Tools and Technology to Study 4D Nucleome
    (David Gilbert / Kazuhiro Maeshima / Jane Skok)
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