Gordon Research Conferences
Meeting Details

Stem Cells & Cancer (GRS)
Gordon Research Seminar

Signals Driving Proliferation, Differentiation, and Self-Renewal in Normal Tissues, Aging, and Cancer


February 11-12, 2017


Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy Site Information


Jeevisha Bajaj & Seerat Bajwa

Application Deadline

The application deadline for this meeting was January 14, 2017. You may still submit an application, which may be considered by the conference chair if there is still room available.

Meeting Description


The Gordon Research Seminar on Stem Cells and Cancer is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.

Mechanisms that drive normal development and regeneration are often deregulated in cancer. Thus, an understanding of signals that regulate stem cell self-renewal and differentiation has clear implications on malignant growth. In this meeting, we will explore genetic, epigenetic, molecular and cellular mechanisms that regulate the growth of normal and malignant stem cells. We will also explore novel approaches to targeting cancer progression and metastasis, such as immunotherapy and inhibiting cancer-niche interactions.

Application Instructions

The meeting will feature approximately 10 talks and 2 poster sessions. All attendees are expected to actively participate in the GRS either by giving an oral presentation or presenting a poster. Therefore, all applications must include an abstract.

The Chairs will select speakers from abstracts submitted by November 11, 2016. Those applicants who are not chosen for talks and those who apply after the deadline to be considered for an oral presentation will be expected to present a poster. In order to participate, you must submit an application by the date indicated in the Application Deadline section above.

Related Meeting

This GRS will be held in conjunction with the "Stem Cells & Cancer" Gordon Research Conference (GRC). Those interested in attending both meetings must submit an application for the GRC in addition to an application for the GRS. Refer to the associated GRC program page for more information.


Meeting Program

1:30 pm - 4:30 pmArrival and Check-in
3:00 pm - 3:15 pmIntroductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair
3:15 pm - 4:00 pmKeynote Session: Stem Cells in Cancer Initiation and Relapse
Discussion Leader: Dmitry Bulavin (Institute of Research on Cancer and Aging in Nice (IRCAN), France)
3:15 pm - 3:50 pmCedric Blanpain (Universite Libre de Bruxelles, Belgium)
"Stem Cells in Cancer Initiation and Relapse"
3:50 pm - 4:00 pmDiscussion
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pmInvestigating Signals Driving Normal and Malignant Growth
Discussion Leader: Toni Celia-Terrasa (Princeton University, USA)
5:30 pm - 5:45 pmJohn Schell (University of Utah, USA)
"Limiting Mitochondrial Pyruvate Entry Increases Intestinal Stem Cells Capacity"
5:45 pm - 5:50 pmDiscussion
5:50 pm - 6:05 pmLyndsay Murrow (University of California, San Francisco, USA)
"Reconstituting the Mammary Stem Cell Niche"
6:05 pm - 6:10 pmDiscussion
6:10 pm - 6:25 pmNikki Lytle (University of California, San Diego, USA)
"Stem Cell Signals Drive Pancreatic Cancer Therapy Resistance"
6:25 pm - 6:30 pmDiscussion
6:30 pm - 6:45 pmSejal Vyas (Harvard Medical School, USA)
"SIRT4 Regulation of Intestinal Homeostasis upon DNA Damage"
6:45 pm - 6:50 pmDiscussion
6:50 pm - 7:05 pmScott Callahan (Memorial Sloan Kettering Cancer Center, USA)
"Cell of Origin Studies of Malignant Melanoma Using both Transgenic Zebrafish and Human Pluripotent Stem Cell-Derived Melanocytes"
7:05 pm - 7:10 pmDiscussion
7:10 pm - 7:25 pmLara Al-zoubi (Institut Curie, France)
"Exploring Mechanisms and Frequency of Spontaneous Mutations in Adult Stem Cells"
7:25 pm - 7:30 pmDiscussion
8:00 pmDinner
7:30 am - 8:30 amBreakfast
9:00 am - 11:00 amCancer Stem Cell Biology
Discussion Leader: Mark Esposito (Princeton University, USA)
9:00 am - 9:15 amToni Celia-Terrasa (Princeton University, USA)
"The miR-199a Pathway Mediates the Evasion of Normal and Cancer Stem Cells from Interferon-Imposed Constraint"
9:15 am - 9:20 amDiscussion
9:20 am - 9:35 amJessie Brown (New York University School of Medicine, USA)
"Cellular Quiescence Confers Multi-Drug Resistance Dependent on TGFβ Signaling in Squamous Cell Carcinoma"
9:35 am - 9:40 amDiscussion
9:40 am - 9:55 amYejing Ge (Rockefeller University, USA)
"At the Crossroads of Wound-Repair and Cancer"
9:55 am - 10:00 amDiscussion
10:00 am - 10:15 amKrithika Badarinath (National Center for Biological Sciences, India)
"Snail Maintains the Undifferentiated Characteristics of Select Cells Within a Heterogenous Tumor"
10:15 am - 10:20 amDiscussion
10:20 am - 10:35 amKyle Spinler (University of California, San Diego, USA)
"Identifying Elements of the Msi2 Network Provides a New Therapeutic Window into Controlling Blast Crisis Chronic Myelogenous Leukemia"
10:35 am - 10:40 amDiscussion
10:40 am - 10:55 amAlastair Davies (University of British Columbia, Canada)
"EZH2 Reprogramming Confers Intrinsic Stem Cell Properties and Developmental Plasticity Driving Neuroendocrine Prostate Cancer"
10:55 am - 11:00 amDiscussion
11:00 am - 12:30 pmPoster Session

Coffee will be served in the poster area from 11:00 am - 11:30 am
12:30 pmLunch
1:30 pm - 2:30 pmMentorship Component: Exploring Diverse Career Options Post-Training
Discussion Leader: Lyndsay Murrow (University of California, San Francisco, USA)
1:30 pm - 2:30 pmPanel Discussion
"Career Options Post-Training"
  • Cedric Blanpain (Universite Libre de Bruxelles, Belgium)
  • Bita Nakhai (National Institute on Aging, NIH, USA)
  • Lenhard Rudolph (Leibniz Institute on Aging - Fritz Lipmann Institute (FLI), Germany)
  • Amy Wagers (Harvard University, USA)
2:30 pm - 3:00 pmEvaluation Period
Fill in GRS Evaluation Forms
3:00 pmSeminar Concludes
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