Gordon Research Conferences
Meeting Details
Search:
  GO

Wnt Signaling
Gordon Research Conference

Wnt Signaling: A Pathway Implicated in Animal Development, Stem Cell Control and Cancer

Dates

August 6-11, 2017

Location

Stoweflake Conference Center
Stowe, VT Site Information

Organizers

Chair:
Roeland Nusse

Vice Chair:
Karl Willert

Application Deadline

Applications for this meeting must be submitted by July 9, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be stated here. Note: Applications for oversubscribed meetings will only be considered by the Conference Chair if more seats become available due to cancellations.

Meeting Description

The 2017 Gordon Research Conference titled "Wnt Signaling: A Pathway Implicated in Animal Development, Stem Cell Control and Cancer" seeks to advance our understanding of how the highly conserved Wnt signaling pathway influences developmental processes and disease. The proposed meeting will cover a broad spectrum of biological systems, approaches and methodologies and bring together a diverse group of scientists, including structural biologists, embryologists, and stem cell and cancer researchers.

Contributors

Meeting Program

Sunday
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmWnt Proteins: Structures and Modifications
Discussion Leader: Roeland Nusse (Stanford University, USA)
7:40 pm - 8:10 pmJean-Paul Vincent (The Francis Crick Institute, United Kingdom)
"Secretion and Release of Wnts"
8:10 pm - 8:20 pmDiscussion
8:20 pm - 8:45 pmYvonne Jones (University of Oxford, United Kingdom)
"Structural Analysis of Wnt Signaling Components"
8:45 pm - 8:55 pmDiscussion
8:55 pm - 9:20 pmRami Hannoush (Genentech, Inc., USA)
"Biochemical Analysis of Wnt Signaling"
9:20 pm - 9:30 pmDiscussion
Monday
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmWnt Signal Transduction
Discussion Leader: Karl Willert (University of California, San Diego, USA)
9:00 am - 9:25 amXi He (Harvard Medical School, USA)
"Novel Regulators of Wnt Signaling"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amWilliam Weis (Stanford University, USA)
"Molecular Mechanisms in Wnt/β-Catenin Signaling"
10:00 am - 10:10 amDiscussion
10:10 am - 10:40 amCoffee Break
10:40 am - 11:05 amMadelon Maurice (University Medical Center Utrecht, The Netherlands)
"Wnt Pathway Tumor Suppressors: Mechanisms and Mutations"
11:05 am - 11:15 amDiscussion
11:15 am - 11:40 amLate-Breaking Topic
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmWnt Signaling at the Membrane
Discussion Leader: Christof Niehrs (German Cancer Research Center (DKFZ), Germany)
7:30 pm - 7:55 pmMichael Boutros (German Cancer Research Center (DKFZ), Germany)
"Secretion of Wnt Signals"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmVivian Budnik (University of Massachusetts Medical School, USA)
"Wnt Signaling in Development"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmMariann Bienz (Medical Research Council, United Kingdom)
"On-Off Switching of the Wnt Enhanceosome"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:30 pmGeneral Discussion
Tuesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmWnt Signaling in the Nucleus
Discussion Leader: Xi He (Harvard Medical School, USA)
9:00 am - 9:25 amKenneth Cadigan (University of Michigan, USA)
"Wnt Signaling in the Nucleus"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amChristof Niehrs (German Cancer Research Center (DKFZ), Germany)
"Novel Regulators of LRP6"
10:00 am - 10:10 amDiscussion
10:10 am - 10:40 amCoffee Break
10:40 am - 11:05 amTerry Yamaguchi (National Cancer Institute at Frederick, NIH, USA)
"Developmental Roles of Wnt Signaling"
11:05 am - 11:15 amDiscussion
11:15 am - 11:40 amLate-Breaking Topic
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:25 pmShort Talk Selected from Poster Abstracts
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCell Biology of Wnt Proteins and Signaling
Discussion Leader: Rami Hannoush (Genentech, Inc., USA)
7:30 pm - 7:55 pmFeng Cong (Novartis, USA)
"Interference with Wnt Signaling"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmEthan Lee (Vanderbilt University, USA)
"A Model for Wnt Receptor Activation by APC"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmDavid Virshup (University of Utah, USA)
"Wnt's Journey to the Membrane"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:30 pmGeneral Discussion
Wednesday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmWnt in Stem Cells and Regeneration
Discussion Leader: Feng Cong (Novartis, USA)
9:00 am - 9:25 amArial Zeng (Chinese Academy of Sciences, China)
"PROCR in Regulating Mammary Stem Cells and Beyond"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amPeter Reddien (Whitehead Institute for Biomedical Research, USA)
"The Role of Wnt Signaling from Muscle in Planarian Regeneration"
10:00 am - 10:10 amDiscussion
10:10 am - 10:40 amCoffee Break
10:40 am - 11:05 amLate-Breaking Topic
11:05 am - 11:15 amDiscussion
11:15 am - 11:40 amLate-Breaking Topic
11:40 am - 11:50 amDiscussion
11:50 am - 12:05 pmShort Talk Selected from Poster Abstracts
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the Next Vice Chair; Fill in Conference Evaluation Forms; Discuss Future Site and Scheduling Preferences; Election of the Next Vice Chair
7:30 pm - 9:30 pmSystems Biology of Wnt Signaling
Discussion Leader: Mariann Bienz (Medical Research Council, United Kingdom)
7:30 pm - 7:55 pmMarc Kirschner (Harvard Medical School, USA)
"Systems Biology of Wnt Signaling"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmLawrence Lum (University of Texas Southwestern Medical Center, USA)
"Interrogating Wnt Signaling with the Help of Large Molecular Libraries"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmMarian Waterman (University of California, Irvine, USA)
"Wnt Signaling Heterogeneity in Cancer"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:30 pmGeneral Discussion
Thursday
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmWnt in Development
Discussion Leader: Kenneth Cadigan (University of Michigan, USA)
9:00 am - 9:25 amEdward Morrisey (University of Pennsylvania, USA)
"Wnt Responsiveness Defines Epithelial and Mesenchymal Niches in the Adult Lung"
9:25 am - 9:35 amDiscussion
9:35 am - 10:00 amBryan Phillips (University of Iowa, USA)
"Asymmetric Cell Division During Development Requires Wnt Signaling and Tight Control of β-Catenin Levels"
10:00 am - 10:10 amDiscussion
10:10 am - 10:40 amCoffee Break
10:40 am - 11:05 amLate-Breaking Topic
11:05 am - 11:15 amDiscussion
11:15 am - 11:25 amShort Talk Selected from Poster Abstracts
11:25 am - 11:30 amDiscussion
11:30 am - 11:40 amShort Talk Selected from Poster Abstracts
11:40 am - 11:45 amDiscussion
11:45 am - 11:55 amShort Talk Selected from Poster Abstracts
11:55 am - 12:00 pmDiscussion
12:00 pm - 12:10 pmShort Talk Selected from Poster Abstracts
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:30 pmGeneral Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmWnt Signaling in Disease
Discussion Leader: Michael Boutros (German Cancer Research Center (DKFZ), Germany)
7:30 pm - 7:55 pmMatthew Warman (Boston Children's Hospital, Harvard University, USA)
"Wnt Signaling in Bone Homeostasis"
7:55 pm - 8:05 pmDiscussion
8:05 pm - 8:30 pmBart Williams (Van Andel Research Institute, USA)
"Wnt Signaling in Skeletal Development and Homeostasis"
8:30 pm - 8:40 pmDiscussion
8:40 pm - 9:05 pmOwen Sansom (Beatson Institute for Cancer Research, United Kingdom)
"Assessing the Impact of Wnt Inhibition on Stem Cells and Tumourigenesis"
9:05 pm - 9:15 pmDiscussion
9:15 pm - 9:30 pmGeneral Discussion
Friday
7:30 am - 8:30 amBreakfast
9:00 amDeparture
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter