Gordon Research Seminar on Cilia, Mucus, and Mucociliary Interactions
will provide a unique and engaging forum for graduate students,
researchers, and trainees from around the world to present their novel
research, learn from the work of others, and to establish new
relationships and collaborations.
cilia and their interactions fulfill important vital functions, such as
critical airway defense in the respiratory
tract. Additionally, mucus, cilia, and/or their interactions also play
necessary roles in diverse organ systems including the gastrointestinal
tract, the reproductive tract, and the brain.
first-time GRS seeks to bring together aspiring scientists engaging in
research related to cilia, mucus, and their interactions throughout the
This GRS was held in conjunction with the "Cilia, Mucus & Mucociliary Interactions" Gordon Research Conference (GRC)
. Refer to the associated GRC program page
for more information.
The conference also gratefully acknowledges a contribution from Bruce Given, MD.
|2:00 pm - 5:00 pm||Arrival and Check-in|
|3:30 pm - 3:45 pm||Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair|
|3:45 pm - 4:30 pm||Keynote Session: Modeling Human Lung Disease and Development Using Pluripotent Stem Cells|
|Discussion Leader: Ana Maria Jaramillo (University of Texas MD Anderson Cancer Center, USA)|
|3:45 pm - 4:15 pm||Hans-Willem Snoeck (Columbia University, USA)|
"Modeling Human Lung Disease and Development Using Pluripotent Stem Cells"
|4:15 pm - 4:30 pm||Discussion|
|4:30 pm - 6:00 pm||Poster Session|
|7:30 pm - 9:30 pm||Composition, Structure, and Function of Cilia and Mucus Throughout
|Discussion Leaders: Luke Bonser (University of California, San Francisco, USA) and Peter Walentek (University of California, Berkeley, USA)|
|7:30 pm - 7:50 pm||Shiaulou Yuan (Yale University School of Medicine, USA)|
"Intraciliary Calcium Oscillations Initiate Vertebrate Left-Right Asymmetry"
|7:50 pm - 8:00 pm||Discussion|
|8:00 pm - 8:20 pm||Eamon Dubaissi (University of Manchester, United Kingdom)|
"Xenopus Epidermal Mucin Forms a Barrier to Infection in Tadpoles"
|8:20 pm - 8:30 pm||Discussion|
|8:30 pm - 8:50 pm||Nathalie Jurisch-Yaksi (Kavli Institute for Systems Neuroscience / Center for Neural Computation, Norway)|
"Motile Cilia Mediated Flow Improves Sensitivity and Temporal Resolution of Olfactory Computations"
|8:50 pm - 9:00 pm||Discussion|
|9:00 pm - 9:20 pm||Amanda Smith (University of North Carolina at Chapel Hill, USA)|
"Investigating SPAG1: A Protein Involved in Pre-Assembly and/or Transport of Dynein Arms"
|9:20 pm - 9:30 pm||Discussion|
|7:30 am - 8:30 am||Breakfast|
|9:00 am - 11:00 am||Generation and Regulation of Cilia, Mucus, and Mucociliary Interactions
in Homeostasis and Pathology|
|Discussion Leaders: Shiaulou Yuan (Yale University School of Medicine, USA) and Gregg Duncan (Johns Hopkins University School of Medicine, USA)|
|9:00 am - 9:20 am||Ximena Bustamante-Marin (University of North Carolina at Chapel Hill, USA)|
"GAS2L2, a Gene Related to PCD, Is Required for Proper Cilia Function and Orientation in Human, Mouse and Xenopus"
|9:20 am - 9:30 am||Discussion|
|9:30 am - 9:50 am||Ana Maria Jaramillo (University of Texas MD Anderson Cancer Center, USA)|
"Different Munc18 Proteins Mediate Baseline and Stimulated Airway Mucin Secretion"
|9:50 am - 10:00 am||Discussion|
|10:00 am - 10:15 am||Joan Antoni Fernandez-Blanco (University of Gothenburg, Sweden)|
"Elastase Modifies the Secretome and Proteome of Bronchoalveolar Epithelial Cells, Inducing Airway Mucus Plugging in Mice"
|10:15 am - 10:20 am||Discussion|
|10:20 am - 10:35 am||Luke Bonser (University of California, San Francisco, USA)|
"Secretory Airway Epithelial Cell Reprogramming Causes Airway Obstruction in Asthma"
|10:35 am - 10:40 am||Discussion|
|10:40 am - 10:55 am||Michael Price (University of Nebraska Medical Center, USA)|
"Redox Activation of Airway-Cilia Localized Protein Phosphatase 1 Drives Alcohol-Induced Ciliary Dysfunction"
|10:55 am - 11:00 am||Discussion|
|11:00 am - 12:30 pm||Poster Session|
|Coffee will be served in the poster area from 11:00 am - 11:30 am|
|1:30 pm - 2:30 pm||Mentorship Component: Research and Career Development|
|Discussion Leader: Petra Pennekamp (Universitätsklinikum Münster, Germany)|
|1:30 pm - 2:30 pm||Panel Discussion|
|"Research and Career Development"|
- Hans-Willem Snoeck (Columbia University, USA)
- Christopher Evans (University of Colorado Denver, USA)
- Amy Firth (University of Southern California, USA)
|2:30 pm - 3:00 pm||Evaluation Period|
|Fill in GRS Evaluation Forms|
|3:00 pm||Seminar Concludes|
Funding for this conference was made possible (in part) by 1R13HL135935-01 from the National Institutes of Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government.