Ethanol Metabolism - I
- Ting-Kai Li (Indiana University of Medicine), Discussion Leader
- John G. Wagner, (University of Michigan), "Kinetics of ethanol elimination in man"
- William Bosron, (Indiana School of Medicine), "Human alcohol dehydrogenase isoenzymes in metabolism"
- Thomas D. Hurley, (Indiana University of Medicine), "Unique features of gastric alcohol dehydrogenase: A view from the structure"
- Charles S. Lieber, (Mount Sinai School of Medicine), "Gastric alcohol dehydrogenase and first-pass metabolism"
- Michael D. Levitt, (Veterans Administration Medical Center, Minneapolis), "Kinetics and mechanism of first-pass metabolism of alcohol"
Ethanol Metabolism - II
- Charles S. Lieber, (Mount Sinai School of Medicine), Discussion Leader
- Magnus Ingelman-Sundberg, (Karolinska Institute), "Ethanol inducible cytochrome P450 2E1. Regulation by ethanol and roles in ethanol metabolism and toxicity"
- Mikko Salaspuro, (University of Helsinki), "Bacterio-colonic pathway for ethanol oxidation"
- Louis G. Lange, (CV Therapeutics), "Non-oxidative and other novel types of ethanol metabolism"
- Regina Pietruszko, (Rutgers University), "Heterogeneity of aldehyde dehydrogenases and their physiological substrates"
- Henry Weiner, (Purdue University), "Active site and potential regulation of class 2 aldehyde dehydrogenase"
Gene Regulation of Alcohol and Aldehyde Dehydrogenases
- Stephen Duncan, (Rockefeller University), Discussion Leader
- Stephen Duncan, (Rockefeller University), "Developmental regulation of hepatic genes"
- Gregg Duester ,(LaJolla Cancer Research Foundation), "Alcohol dehydrogenase and retinoic acid synthesis in mouse embryos"
- David W. Crabb, (Indiana University School of Medicine), "Regulation of human aldehyde dehydrogenase 2 gene expression"
- You-Chen Chao, (Tri Service General Hospital, Taipei), "Alcohol and aldehyde dehydrogenase and P450 2E1 genotypes and liver damage"
Oxidative Stress and Liver Injury
- Arthur I. Cederbaum, (Mount Sinai School of Medicine), Discussion Leader
- Arthur I. Cederbaum, (Mount Sinai School of Medicine), "Ethanol and generation of reactive oxygen species"
- Lester A. Reinke, (University of Oklahoma Health Sciences Center), "Reactive free radical generation of ethanol-fed rats"
- Neil Kaplowitz, (University of Southern California School of Medicine), "Ethanol and glutathione homeostasis"
- Ronald G. Thurman, (University of North Carolina), "Evidence for the role of endotoxin, Kupfer cells and free-radicals in alcoholic liver injury"
- Hidekazu Tsukamoto, (Case Western Reserve University), "Oxidative stress and alcoholic liver fibrogenesis after continuous intragastric infusion of alcohol"
- Mark Zern, (Thomas Jefferson University), "Therapeutic intervention for oxidative stress"
Search for Genes Which May Determine Susceptibility to Alcoholism
- Jeanne M. Wehner, (University of Colorado), Discussion Leader
- Henry Begleiter, (State University of New York), "Collaborative study of the genetics of alcoholism"
- David Goldman, (NIAAA , NIH), "Candidate genes for alcoholism"
- John Crabbe, (Veterans Administration), "Use of recombinant inbred mouse strains to map alcohol susceptibility and resistant genes"
- Thomas E. Johnson, (University of Colorado), "Identifying, confirming and cloning genes specifying sensitivety to ethanol in long-sleep and short-sleep mice"
- Lucinda G. Carr ,(Indiana University School of Medicine), "Molecular associations of alcohol-seeking behavior in rat lines selectively bred for high and low voluntary ethanol drinking"
Ethanol and Signal Transduction
- Emanuel Rubin, (Thomas Jefferson University), Discussion Leader
- John H. Exton, (Vanderbilt University), "Lipid cell signalling"
- J. B. Hoek, (Thomas Jefferson University), "Effects of ethanol on membrane-associated signal transduction"
- Ivan Diamond, (University of California, SF), The role of phosphorylation in mediating ethanol responses in neural cells"
- Gary S. Wand, (The Johns Hopkins University School of Medicine), "G protein alterations in alcoholism"
- Anna Mae Diehl, (The Johns Hopkins University School of Medicine), "Effects of ethanol on signal transduction during liver regeneration"
- Craig J. McClain, (University of Kentucky Medical Center), Cytokines in experimental liver injury"
Protein - Acetaldehyde Adducts
- Lawrence Lumeng, (Indiana University School of Medicine), Discussion Leader
- Renee C. Lin,(Indiana University School of Medicine), "Delta-4-3-ketosteroid 5 reductase (The 37 KD protein) as a target for acetaldehyde modificationin in rat liver in vivo"
- Dean J. Tuma, (University of Nebraska), "Acetaldehyde-protein adducts"
- Yedi Israel, (Thomas Jefferson University), "Acetaldehyde-modified epitropes in the liver"
- Onni J. Niemela, (University of Oulu), "Acetaldehyde adducts in erythrocytes and in bone marrow precursors"
- Simon Worrall, (University of Queensland), "Liver damage in ethanol-fed rats injected with acetaldehyde modified proteins"
Ethanol and Fibrogenesis
- D. Montgomery Bissell, (University of California, SF), Discussion Leader
- David A. Brenner, (University of North Carolina), "Multiple regulatory elements in the collagen alpha 1(I) gene"
- Marcus Rojkind, (Albert Einstein College of Medicine), "The role of acute phase response in liver fibrosis"
- Catherine H. Wu, (University of Connecticut), "Effect of ethanol on type 1 collagen promoter activity in transgenic mice"
- Mario Chojkier, (University of California, SD), "Lipid peroxidation and fibrogenesis"
- Scott L. Friedman, (University of California, SF), "Stellate cell activation and fibrogenesis"
- Jacquelyn J. Maher, (University of California, SF), "Effects of acetaldehyde on collagen gene transcription"
Special Lecture
- D. Montgomery Bissell, (University of California, SF)
Protein Metabolism and Protein Trafficking
- Dean J. Tuma, (University of Nebraska), Discussion Leader
- Emanuel Rubin, (Thomas Jefferson University), "Direct interactions of ethanol with proteins"
- Steven Schenker, (University of Texas), "Ethanol oxidative stress and the fetus"
- Carol A. Casey, (University of Nebraska), "Effects of ethanol on protein tracking"
- Terence M. Donohue, (University of Nebraska), "Ethanol and catabolism of proteins"
- Raj Lakshman, (VA Medical Center), "Ethanol and protein glycosylation"
|