Cell Structure and Microenvironments |
SUNDAY PM |
Discussion Leader: Jim Clegg, Bodega Bay Marine Laboratory, Univ. Of California-Davis
- Evolving Concepts of Cell Structure and the Intracellular Milieu: A Historical Perspective
Jim Clegg (Bodega Bay Marine Laboratory, Univ. Of California, Davis)
- Organization of Cellular Water
Adrian Parsegian (Physical Science Laboratory, NIH)
- Control of Intracellular Transport by the Cytoplasmic Architecture
Kate Luby-Phelps (Dept. Of Physiology, Univ. Of Texas Southwestern Medical Center)
Cellular Mobility and Intracellular Transport |
MONDAY AM |
Discussion Leader: Kate Luby-Phelps (Dept. Of Physiology, Univ. Of Texas Southwestern Medical Center)
- Imaging Intracellular Trafficking
Thomas Jovin (Dept. Of Molecular Biology, Max Planck Inst. For Biophysical Chemistry, Göttingen)
- Cytokinesis and Cell Locomotion
Kevin Burton (Science and Technology Center, Carnegie Mellon Univ.)
- Axonal Transport
Scott Brady (Dept. of Cell Biology and Neuroscience, Univ. of Texas Southwest Medical Center)
- Cytoskeletal Function in Plant Cells
Mel Schindler (Dept. Of Biochemistry, Michigan State Univ.)
Molecular Basis for Channeled Metabolism |
MONDAY PM |
Discussion Leader: Paul Srere, VA Medical Center, Dallas, TX
- Principles of Protein-Protein Interactions
Susan Jones (Department of Biochemistry, University College, London)
- Protein-Protein Interaction and the Molecular Mechanism of Substrate Channelling in 2-Oxo Acid Dehydrogenase Complexes
Richard Perham (Dept. Of Biochemistry, Univ. Of Cambridge)
- Tryptophan Synthase: Allosteric Regulation of Substrate Channeling
Michael Dunn (Dept. Of Biochemistry, Univ. Of California-Riverside)
TUESDAY AM |
Non-invasive Approaches for Exploring Macromolecular and Cellular Organization |
Discussion Leader: Douglas Kell, Institute of Biological Sciences, Univ. Of Wales, Aberystwyth
- Luminescent Indicator and Reporter Genes
Tony Campbell (Dept. Of Medical Biochemistry, Univ. Of Wales, Cardiff)
- Detection and localization of genes and gene products by flourescence microscopy in prokaryotes: linking genotype and phenotype?
Nanne Nanninga (Institute of molecular & cellular biology, University of Amsterdam)
- Spectroscopic Analysis of Proteins in vivo
Kevin Brindle (Dept. Of Biochemistry, Univ. Of Cambridge)
- Detection of Protein-Protein Interactions with the Reverse Two Hybrid System
Marc Vidal (Massachusetts General Hospital Cancer Center, Harvard. Univ.)
Enzyme Organization and Channeled Metabolism |
TUESDAY PM |
Discussion Leader: Harvey Knull (University of North Dakota)
- Protein-Protein Interactions Within the Bcl-2 Family: Importance in the Regulation of Apoptosis
Caroline Dive (Univ. Of Manchester)
- Structural and Functional Organization of Polyketide Synthases
Peter F. Leadlay (Univ. Of Cambridge)
- Production and Modeling of Krebs TCA Cycle Enzyme Fusions to Study the Metabolon Hypothesis
Christian Vélot (VA Medical Center, Dallas, TX)
Organization of Gene Expression |
WEDNESDAY AM |
Discussion Leader: Chris Mathews, Dept. Of Biochemistry and Biophysics, Oregon State Univ.
- Nucleotide/DNA Synthesis
Chris Mathews (Dept. Of Biochemistry and Biophysics, Oregon State Univ.)
- Nucleosome Assembly
Jerry Workman (Dept. Of Biochemistry and Molecular Biology, Pennsylvania State Univ.)
- Intracellular Localization of mRNAs
Natalie Cohen (Dept. Of Molecular Pharmacology and Toxicology, Univ. Of Southern California)
- Sensing Stress and Protein Damage by Heat Shock Transcription Factors and Molecular Chaperones
Rick Morimoto (Dept. Of Biochemistry, Molecular Biology and Cell Biology, Northwestern Univ.)
Organization and Compartmentation of Glycolysis and Glycogen Metabolism |
WEDNESDAY PM |
Discussion Leader: John Wilson, Dept. Of Biochemistry, Michigan State Univ.
- Discrete Functions of Hexokinase Isozymes
Chris Newgard (Dept. Of Biochemistry, Univ. Of Texas Southwestern Medical Center)
- Translocation of Glucokinase
Kasim Mookhtiar (Dept. Of Metabolic Diseases, Bristol-Myers Squibb Pharmaceutical Research Institute)
- Glycogen Synthesis
Joan Guinovart (Dept. Of Biochemistry and Molecular Biology, Univ. Of Barcelona)
Integrative Biology |
THURSDAY AM |
Discussion Leader: Rick Welch, Univ. of Maryland Baltimore County
- Genome Functional Analysis in the Post-Genomic Era
Steve Oliver (Dept. Of Biochemistry and Applied Molecular Biology, Univ. Of Manchester)
- Hierarchical Control Analysis
Hans Westerhoff (Free Univ., Amsterdam)
- New Approaches to Defining the Flavonoid Metabolon
Brenda Shirley (Dept. Of Biology, Virginia Tech Univ.)
- Gene Knockouts in Animals
Bé Wieringa (Catholic Univ. Of Nijmegen)
Organization of Signaling Pathways |
THURSDAY PM |
Discussion Leader: Susan Jaken (W. Alton Jones Cell Science Center)
- Protein Kinase C: Isozymes, Substrates, and Translocation
Susan Jaken (W. Alton Jones Cell Science Center)
- Signal Transduction Pathways that Regulate Neuronal Differentiation, Survival, and Adaptive Responses
Michael Greenberg (Div. of Cell Neurosciences, Children's Hospital, Harvard Univ.)
- Neuronal Targeting of Kinase Phosphatase Signaling Complexes
John D. Scott(Howard Hughes Medical Institute, Vollum Institute)