SUNDAY |
7:30 - 9:30 pm | Large / complex systems |
| Jamie Cate (UC Berkeley) "Structural Studies of the Bacterial Ribosome" |
| Joachim Frank (Wadsworth Inst.) "The Ribosome -- a Molecular Machine in Motion as Seen by Cryo-EM" |
| Jean-Louis Viovy (Institut Curie) "Single molecule studies: from DNA physics to chromatin biology" |
| Zippi Shakked (Weizmann Institute of Science) (chair and speaker) "High-resolution view of DNA bending by an adenine-thymine tract" |
MONDAY |
10:00 am | Photo |
9:00 am - 12:30 pm | DNA structure, mechanics |
| Wilma Olson (Rutgers University) "DNA Mechanics and Gene Regulation" |
| Carlos Bustamante (UC-Berkeley) "Follwing the packaging of DNA by individual phage phi29 particles using optical tweezers" |
| Anjum Ansari (U. Illinois-Chicago) "Hairpin formation in Polynucleotides: A Simple Folding Problem?" |
| Loren Williams (Georgia Tech) "Nucleic Acid-Cation Binding Motifs" |
| Victor Bloomfield (U. Minnesota) (chair and discussion leader) |
7:30 - 9:30 pm | Molecular motors / machines |
| Terrence Strick (Cold Spring Harbor) "Direct observation of mechanically and enzymatically-driven DNA denaturation" |
| Andrew Marcus (University of Oregon) "Cytoskeletal-Assisted Dynamics of the Mitochondrial Reticulum in Living Cells by Fourier Imaging Correlation Spectroscopy" |
| Toshio Yanagida (Osaka U.) "Single Molecule Nano-Bioscience" |
| Michelle Wang (Cornell) (chair and speaker) "Unpacking DNA: Forced Disruption of Nucleosomes" |
TUESDAY |
9:00 am - 12:30 pm | RNA structure, folding, stability |
| Ignacio Tinoco (UC-Berkeley) "Unfolding RNA by force - the biological way" |
| Jamie Williamson (Scripps) "Assembly of the 30S ribosomal suunit" |
| Olke Uhlenbeck (U. Colorado) "tRNA Conformity in Translation" |
| (open slot reserved) |
| Sarah Woodson (Johns Hokins University) (chair and speaker) "Counterion-induced collapse of RNA" |
7:30 - 9:30 pm | Milieu |
| Barbara Baird (Cornell) "Participation of plasma membrane domains in IgE receptor signaling" |
| Gary Pielak (U. North Carolina) "An unfolded protein that folds in cells" |
| Ken Dill (UCSF) (chair and speaker) "New Models of Water, the Hydrophobic Effect, and Ion Solvation" |
WEDNESDAY |
9:00 am - 12:30 pm | Protein structure, prediction, folding |
| Valerie Daggett (U. Washington) "Protein unfolding/folding at atomic resolution" |
| Andreas Matouschek (Northwestern Univ.) "Protein unfolding in the cell" |
| Steve Mayo (Caltech) "Electrostatic Models for Computational Protein Design" |
| Doug Barrick (John Hopkins University) "Structural and thermodynamic plasticity in a modular protein: the ankyrin repeat domain of drosophila notch" |
| Robert Baldwin (Stanford) (chair and discussion leader) |
7:30 - 9:30 pm | Protein-protein interactions |
| Michelle Arkin (Sunesis Pharmaceuticals) "Discovery of small-molecule inhibitors of protein-protein interactions: a case study" |
| Ishwar Radhakrishnan (Northwestern University) "Protein-protein interactions in eukaryotic transcription regulation" |
| Deborah Leckband (U. Illinois) (chair and speaker) "What can force measurements tell us about protein interactions?" |
THURSDAY |
9:00 am - 12:30 pm | Protein-nucleic acid interactions |
| Juli Feigon (UCLA) "RNA-protein structures involved in eukaryotic ribosome biogenesis" |
| Smita Patel (Rutgers U.) "Mechanistic Studies of Helicases" |
| Richard W. Roberts (California Institute of Technology) "Recognition of RNA Hairpins by Peptides: Regulation of Transcription via RNA-Ligand Interactions" |
| Tim Lohman (Washington U.) "SF1 Helicase-catalyzed DNA Unwinding" |
| Peter von Hippel (U. Oregon) (chair and discussion leader) |
7:30 - 9:30 pm | Keynote speaker |
| Harold Scheraga (Cornell) "Ab initio prediction of protein structure by global optimization of potential energy" |