SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | GENETICS AND RISK |
7:30 pm - 8:00 pm | Discussion Leader: Allan Balmain, UCSF
"Mouse Models for the Identification of Tumor Susceptibility Gene Networks" |
8:00 pm - 8:30 pm | Jeff Trent, Translational Genomics Research Institute |
8:30 pm - 9:00 pm | Donna Albertson, UCSF
"Inbreds, Tumors and Genomic Variation" |
9:00 pm - 9:30 pm | General Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NEW APPROACHES TO PRE-CLINICAL DRUG DEVELOPMENT |
9:00 am - 9:30 am | Discussion Leader: Truman Brown, Columbia University
"Predicting Treatment Response in Non-Hodgkin's Lymphoma with 31 P MRS" |
9:30 am - 10:00 am | Roland Wolf, University of Dundee
"Molecular and Genetic Approaches for the Acceleration of Anticancer Drug Development" |
10:00 am | Coffee Break / Photo |
10:30 am - 11:00 am | Peter Lassota, Novartis
"Visible light imaging in Oncology Drug Development: the Hypes, the Fears and the Reality" |
11:00 am - 11:30 am | Lewis Chodosh, University of Pennsylvania
"Genetically Engineered Mouse Models for Breast Cancer Progression and Target Validation" |
11:30 am - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 6:00 pm | Free Time |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NEW HORIZONS IN CANCER THERAPY |
| Discussion Leader: Robert Kramer, Bristol-Myers Squibb |
7:30 pm - 8:00 pm | Greg Plowman, Exelixis
"A Model Systems Approach to Cancer Target Discovery" |
8:00 pm - 8:30 pm | Richard Kolesnick, Memorial Sloan Kettering
"Impacting the Vascular Component of the Tumor Response to Ionizing Radiation" |
8:30 pm - 9:00 pm | Wadih Arap, MD Anderson Cancer Center
"Molecular Targets in Cancer and Obesity" |
9:00 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | RESISTANCE TO TARGETED THERAPIES |
9:00 am - 9:30 am | Discussion Leader: Ian Tannock, Ontario Cancer Institute
"Limited Penetration of Drugs in Tumor Tissue and Repopulation of Surviving Tumor Cells as Important and Neglected Causes of Drug Resistance" |
9:30 am - 10:00 am | Susan Bates, NCI
"On the Balance: Weighing ABCG2 Against Other ABC Transporters in Drug Resistance" |
10:00 am | Coffee Break |
10:30 am - 11:00 am | John Isaacs, Johns Hopkins
"Enhanced Redundancy in Akt and Map-Kinase Induced Survival of Malignant
Versus Normal Prostate Epithelial Cells" |
11:00 am - 11:30 am | Rachel Schiff, Baylor College of Medicine
"Breast Cancer Endocrine Resistance: The Role of Cross-talk between Estrogen Receptor and Growth Factor Receptor Pathways" |
11:30 am - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | BREAST CANCER: PREVENTION AND TREATMENT |
7:30 pm - 8:00 pm | Discussion Leader: Nancy Davidson, Johns Hopkins
"Epigenetic Gene Regulation in Breast Cancer" |
8:00 pm - 8:30 pm | Chris Benz, Buck Institute
"Discovery and Development of Novel Therapeutics Targeting HER2-Positive Breast Cancer" |
8:30 pm - 9:00 pm | Barbara Weber, University of Pennsylvania
"Genomic Approaches Breast Cancer Target Discovery" |
9:00 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | NEW APPROACHES TO SCREENING AND TOX PROFILING |
9:00 am - 9:30 am | Alec Wood, Novartis
"Protein Deacetylase Inhibitors as Novel Cancer Drug Candidates" |
9:30 am - 10:00 am | Robert Shoemaker, NCI
"Targeting Transcription Factors for Anticancer Drug Discovery" |
10:00 am | Coffee Break |
10:30 am - 11:00 am | George Natsoulis, ICONIX
"Analysis of a 13,000 Microarray Database: Derivation of Gene Signatures fro Drug Effects and Analysis of the Network They Form" |
11:00 am - 11:30 am | TBA |
11:30 am - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | TOOLS OF TRANSLATIONAL RESEARCH |
7:30 pm - 8:00 pm | Jeanne Link, University of Washington
"Imaging and Targeted Cancer Therapy: Help to Move Molecular Therapeutics from the Bench to the Bedside; Imaging Approaches: Possibilities and Limitations" |
8:00 pm - 8:30 pm | Discussion Leader: David Mankoff, University of Washington
"Imaging and Targeted Cancer Therapy: Help to Move Molecular Therapeutics from the Bench to the Bedside; Applications of Imaging to Clinical Therapy and Clinical Trials" |
8:30 pm - 9:00 pm | Robert Gillies, Arizona Cancer Center "Monitoring Therapy REsponse with MRI" |
9:00 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | STROMAL CELLS AND ENDOTHELIUM |
9:00 am - 9:30 am | Discussion Leader: Joe Gray, Lawrence Berkeley National Laboratory
"Genomic Guides to Therapeutic Targets" |
9:30 am - 10:00 am | Mina Bissell, Lawrence Berkeley National Laboratory
"Thinking in 3-D Dimensions for Testing Chemotherapeutics" |
10:00 am | Coffee Break |
10:30 am - 11:00 am | Robert Kramer, Bristol-Myers Squibb
"Beyond Gleevec, the Next Generation of Kinase Inhibitors" |
11:00 am - 11:30 am | Yasumichi Hitoshi
"Aurora Kinase Inhibitors" |
11:30 am - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | RATIONAL COMBINATION THERAPY |
7:30 pm - 8:00 pm | Discussion Leader: Yvesses Pommier, NCI |
8:00 pm - 8:30 pm | Ed Sausville, NCI
"Pre Clinical Modeling of Combination Treatments: Fantasy or Requirement" |
8:30 pm - 9:00 pm | Michaele Christian, NCI |
9:00 pm - 9:30 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |