SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Phototransduction |
7:30 pm - 7:45 pm | Discussion Leader: Steve Lockley (University of Surrey, U.K.) |
7:45 pm - 8:20 pm | Susan Doyle (Department of Biology, University of Virginia, U.S.A.) "Circadian Responses to Light in the Rpe65 Knockout Mouse" |
8:20 pm - 8:55 pm | Rob Lucas (School of Biological Science, University of Manchester, U.K.) "Functions and mechanisms of inner retinal photoreceptors in mammals" |
8:55 pm - 9:30 pm | Russell van Gelder (Department of Ophthalmology, Washington University, U.S.A.)
"Non-visual photoreception: learning from the pupil" |
MONDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regulation of gene expression |
9:00 am - 9:15 am | Discussion Leader: David Klein (National Institute of Child Health and Human Development, U.S.A.) |
9:15 am - 9:55 am | David Carter (University of Cardiff, Wales, U.K)
"Rhythmic Transcription In Transgenic Rats" |
9:55 am - 10:35 am | Estela Munoz (National Institutes of Mental Health, NIH, U.S.A.)
"Pandora's E-Box" |
10:35 am - 11:10 am | Coffee Break |
11:10 am - 11:50 am | Gianluca Tosini (Department of Neuroscience, Morehouse University of Medicine, U.S.A.)
"Analysis of gene expression in the rat pineal and retina" |
11:50 am - 11:55 am | Discussion Leader: Liz Maywood (MRC Laboratory of Molecular Biology, Cambridge, UK) |
11:55 am - 12:30 pm | David Klein (National Institute of Child Health and Human Development, U.S.A.) |
12:45 pm | Lunch / Photo |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Developmental regulation of gene expression |
7:30 pm - 7:45 pm | Discussion Leader: Greg Cahill (Department of Biology & Biochemistry, University of Houston, U.S.A.) |
7:45 pm - 8:20 pm | Jennifer Liang (Case Western Reserve University, U.S.A.) "Form to Function: Organogenesis of the zebrafish pineal" |
8:20 pm - 8:55 pm | Yoav Gothilf (Department of Zoology, Tel-Aviv University, Israel) "Homeobox-Clock proteins interaction, a mechanism for pineal-specific and rhythmic expression of aanat" |
8:55 pm - 9:30 pm | Takahisa Furukawa (Osaka Bioscience Institute, Osaka, Japan)
"Roles of Crx and Otx2 homeobox genes in photoreceptor cell differentiation and pineal gland development" |
TUESDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Regulation of melatonin synthesis |
9:00 am - 9:15 am | Discussion Leader: Horst Korf (Institute of Anatomy, Frankfurt, Germany) |
9:15 am - 9:55 am | Valerie Simonneaux (Department of Neuroscience, University of Strasbourg, France)
"Pineal melatonin synthesis: common principles - species differences" |
9:55 am - 10:35 am | Surajit Ganguly (National Institute of Child Health and Human Development, U.S.A.) "Dual phosphorylation of AANAT is required for 14-3-3-dependent activation" |
10:35 am - 11:10 am | Coffee Break |
11:10 am - 11:50 am | Fabrice Morin (National Institute of Child Health and Human Development, U.S.A.) "Interaction of the acetyl-CoA synthesizing enzyme ATP-citrate lyase with the AANAT/14-3-3 complex: involvement in acetyl-CoA channeling and melatonin production" |
11:50 am - 12:30 pm | Mike Iuvone (Department of Pharmacology, Emory University School of Medicine, U.S.A.)
"Clocks, light, second messengers and AANAT regulation in retina" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Circadian mechanisms and entrainment |
7:30 pm - 7:45 pm | Discussion Leader: Jorg Stehle (Institute of Anatomy, Frankfurt, Germany) |
7:45 pm - 8:20 pm | Steve Reppert (Department of Neurobiology, University of Massachusetts Medical School, U.S.A.)
"A Four-Dimensional Circadian Clock" |
8:20 pm - 8:55 pm | Carla Green (Department of Biology, University of Virginia, U.S.A.) "Post-transcriptional control mechanisms in the vertebrate circadian clock" |
8:55 pm - 9:30 pm | David Whitmore (Department of Anatomy & Developmental Biology, University College London, U.K.) "Eyes are for the birds" |
WEDNESDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Photoperiodism |
9:00 am - 9:15 am | Discussion Leader: Benoit Malpaux (I.N.R.A., Nouzilly, France) |
9:15 am - 9:55 am | Andrew Loudon (School of Biological Science, University of Manchester, U.K.)
"Photoperiodic time measurement in major body organs in a seasonal mammal" |
9:55 am - 10:35 am | Peter Morgan (Rowett Research Institute, Aberdeen, Scotland, U.K.) "The DTMN: a hypothalamic centre of seasonal timing" |
10:35 am - 11:10 am | Coffee Break |
11:10 am - 11:50 am | Roland Brandstatter (School of Biosciences, University of Birmingham, U.K.) "Time coding mechanisms in birds" |
11:50 am - 12:30 pm | Jon Johnston (University of Aberdeen, Scotland, U.K.) "Photoperiodic regulation of gene expression in the suprachiasmatic nuclei and pars tuberalis of seasonal mammals" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Physiology and pharmacology of melatonin receptors |
7:30 pm - 7:45 pm | Discussion Leader: David Sugden (London, UK) |
7:45 pm - 8:20 pm | Charlotte von Gall (J.W. Goethe University, Institute of Anatomy, Frankfurt) "Melatonin regulates clock gene expression in the mouse pars tuberalis via the Mel1a receptor" |
8:20 pm - 8:55 pm | Mirielle Masson-Pevet (Department of Neuroscience, University of Strasbourg, France)
"A morpho-physiological approach of the MT1 receptor" |
8:55 pm - 9:30 pm | Margarita Dubocovich (Department of Molecular Pharmacology, Northwestern University Medical School, U.S.A.)
"Modulation of Circadian Rhythms Through Activation of MT2 Melatonin Receptors" |
THURSDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | Therapeutic uses of melatonin |
9:00 am - 9:15 am | Discussion Leader: Ken Wright (University of Colorado) |
9:15 am - 9:55 am | Debra Skene (University of Surrey, U.K.)
"Human melatonin PRC in free-running blind subjects" |
9:55 am - 10:35 am | Eus van Someren (Netherlands Institute for Brain Research and VU University Medical Center, Amsterdam, The Netherlands)
"Nocturnal and diurnal consequences of long-term light and melatonin treatment in demented elderly" |
10:35 am - 11:10 am | Coffee Break |
11:10 am - 11:50 am | David Blask (Bassett Research Institute)
"Melatonin: a circadian anticancer signal in humans, its suppression by light-at-night, and implications for cancer risk and therapy" |
11:50 am - 12:30 pm | Philippe Delagrange (Servier)
"Therapeutic perspectives for melatonin ligands: lessons from animal models" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | Keynote lecture |
7:30 pm - 8:00 pm | Discussion Leader: Anna Wirz-Justice (Centre for Chronobiology, Basel University, Switzerland) |
8:00 pm - 9:30 pm | Jo Arendt (University of Surrey, U.K.)
"Melatonin" |
FRIDAY |
7:45 am - 8:30 am | Breakfast |
9:00 am | Departure |