SUNDAY |
4:00 pm - 8:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:45 pm) |
6:00 pm | Dinner |
7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
7:40 pm - 9:00 pm | REGULATION OF MELATONIN PRODUCTION |
7:40 pm - 7:50 pm | Discussion Leader: Helena Illnerova, Ph.D (Institute of Physiology, Prague) |
7:50 pm - 8:10 pm | Anthony K. Ho, Ph.D (University of Alberta, Edmonton) "The role of Sik/Torc signaling pathway in regulating gene expression in the rat pineal gland" |
8:10 pm - 8:20 pm | Discussion |
8:20 pm - 8:40 pm | Jorg H. Stehle, Ph.D (University of Frankfurt, Germany) "Illuminating molecular details of dynamics in the human pineal gland" |
8:40 pm - 8:50 pm | Discussion |
8:50 pm - 9:00 pm | General Discussion |
9:00 pm - 9:30 pm | HOT TOPICS SESSION #1 |
| (Speakers selected from posters) |
| Discussion Leader: David C. Klein (NICHD, NIH, Bethesda, MD) |
9:00 pm - 9:10 pm | Samuel Clokie (NICHD, NIH, Bethesda, MD) "miRNAs in the rodent pineal gland" |
9:10 pm - 9:15 pm | Discussion |
9:15 pm - 9:25 pm | Dave Lanoix (INRS-Institut Armand-Frappier, Laval, Quebec, Canada) "Protective effects of human placental melatonin in normal pregnancy" |
9:25 pm - 9:30 pm | Discussion |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:30 am | Group Photo |
9:00 am - 12:30 pm | CIRCADIAN CLOCKS IN THE RETINA |
9:00 am - 9:10 am | Discussion Leader: Gianluca Tosini (Morehouse School of Medicine, Atlanta, GA, USA) |
9:10 am - 9:30 am | Doug McMahon (Vanderbilt University, Nashville TN) "Keeping an Eye on the Time and Keeping the Eye on Time: Mechanisms of a Retinal Circadian Clock" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Chad R. Jackson (Emory University, Atlanta, GA) "Rhythmic Regulation of Retinal Gene Expression by Dopamine" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:45 am | Joseph C. Besharse (Medical College of Wisconsin, Milwaukee, WI) "Circadian Regulation of Photoreceptor Outer Segment Turnover" |
10:45 am - 10:55 am | Discussion |
10:55 am - 11:15 am | Christophe P. Ribelayga (The University of Texas Medical School at Houston, Houston, TX) "Identification of a circadian clock-controlled rod pathway in the mammalian retina" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Cara M. Altimus (Johns Hopkins University, Baltimore, MD) "Cellular dissection of circadian photoreception" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:15 pm | P. Michael Iuvone (Emory University School of Medicine, Atlanta, GA) "A novel role for N-acetylserotonin" |
12:15 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | NEW DEVELOPMENTS IN PINEAL DEVELOPMENTAL BIOLOGY |
7:30 pm - 7:35 pm | Discussion Leader: Maria Serón-Ferré (Universidad de Chile, Santiago, Chile) |
7:35 pm - 7:55 pm | Joshua T. Gamse (Vanderbilt University, Nashville, TN) "Melatonin controls the onset of gene expression in the developing zebrafish brain" |
7:55 pm - 8:00 pm | Discussion |
8:00 pm - 8:20 pm | Margaret J. Ochocinska (NICHD, NIH, Bethesda, MD) "NeuroD1 control of gene expression in the mammalian pineal and retina" |
8:20 pm - 8:25 pm | Discussion |
8:25 pm - 8:45 pm | Diego Bustos (NICHD, NIH, Bethesda, MD) "The biology of eyes absent homolog 2 (Drosophila) in the pineal gland" |
8:45 pm - 9:00 pm | Discussion |
9:00 pm - 9:20 pm | Martin F. Rath (University of Copenhagen, Copenhagen, Denmark) "Homeobox genes in the developing and adult pineal gland" |
9:20 pm - 9:25 pm | Discussion |
9:25 pm - 9:30 pm | General Discussion |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:30 pm | CIRCADIAN CLOCKS, MELATONIN AND METABOLISM I |
9:00 am - 9:10 am | Discussion Leader: Andrew Loudon (University of Manchester, Manchester, UK) |
9:10 am - 9:30 am | Eleanor M. Scott (University of Leeds, Leeds UK) "Clock Gene Polymorphisms and Obesity" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Hélène Duez (Institut Pasteur de Lille, Lille, France) "The nuclear receptors Rev-erbs and RORs integrate circadian rhythms and metabolism" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:45 am | Akhilesh B. Reddy (University of Cambridge Metabolic Research Labs, Cambridge, UK) "Circadian Regulation of Molecules and Metabolism" |
10:45 am - 10:55 am | Discussion |
10:55 am - 11:15 am | Frank A.J.L. Scheer (Harvard Medical School/BWH, Boston, MA) "Adverse Metabolic and Endocrine Consequences of Circadian Misalignment in Humans" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | Hindrik Mulder (Lund University Diabetes Center, Malmö, Sweden) "Melatonin Receptors, Islet Biology, and Type 2 Diabetes" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:05 pm | Hot Topics Speaker (selected from the posters) Ariel Poliandri (Imperial College London, London, UK) "Receptor Interacting Protein 140 regulates the circadian clock by co-activation of Retinoid-Related Orphan Receptor alpha" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | CELLULAR MECHANISMS OF MELATONIN ACTION |
7:30 pm - 7:40 pm | Discussion Leader: Margarita L. Dubocovich (School of Medicine and Biomedical Sciences, University at Buffalo) |
7:40 pm - 8:00 pm | Paula A. Witt-Enderby (Duquesne University, Pittsburgh, PA) "Melatonin and Hormone Replacement Therapy in a Preclinical Model of Mammary Cancer" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | Vincent M. Cassone (University of Kentucky, Lexington, KY) "The Pineal Gland Regulates Bird Song Control Structures and Song Behavior" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Stephano Comai (McGill University, Montreal, Canada) "Role of MT2 Receptors in Sleep Regulation" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:40 am | CIRCADIAN CLOCKS, MELATONIN AND METABOLISM II |
9:00 am - 9:10 am | Discussion Leader: Paul D. Heideman (College of William and Mary, Williamsburg, VA) |
9:10 am - 9:30 am | Takashi Yoshimura (Nagoya University, Nagoya, Japan) "Photoperiodic Transduction in the Mediobasal Hypothalamus" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Sandrine M. Dupré (University of Manchester, Manchester, UK) "Photoperiodic Control of Pars Tuberalis Gene Expression" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:45 am | Valérie Simonneaux (University of Strasbourg, Strasbourg, France) "Melatonin regulation of seasonal reproduction in rodents" |
10:45 am - 10:55 am | Discussion |
10:55 am - 11:15 am | Timothy J. Bartness (Georgia State University, Atlanta, GA) "Photoperiodic Control of Adipose Tissues" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:45 am | David A. Bechtold (University of Manchester, Manchester, UK) "GPR50: Role in Metabolic Regulation and Torpor" |
11:45 am - 11:55 am | Discussion |
11:55 am - 12:00 pm | General Discussion |
12:00 pm - 12:30 pm | HOT TOPICS SESSION #2 |
| (Speakers selected from posters) |
| Discussion Leader: Megan M. Mahoney (University of Illinois, Urbana, IL) |
12:00 pm - 12:10 pm | Caroline Ancel (INCI, Strasbourg, France) "The role of RFRP peptides in the seasonal regulation of reproduction in the Syrian hamster" |
12:10 pm - 12:15 pm | Discussion |
12:15 pm - 12:25 pm | Le Yu (University of Edinburgh, Edinburgh, Scotland) "Technologies to identify melatonin regulated genes in the sheep pars tuberalis using next generation transcriptome sequencing" |
12:25 pm - 12:30 pm | Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | MELATONIN, CIRCADIAN CLOCKS, AND CNS DISEASES |
7:30 pm - 7:40 pm | Discussion Leader: Elizabeth S. Maywood (MRC-LMB, Cambridge UK) |
7:40 pm - 8:00 pm | Sarah H. Elsea (Virginia Commonwealth University School of Medicine, Richmond, VA) "To Sleep, Perchance to Dream... not in Smith-Magenis Syndrome" |
8:00 pm - 8:10 pm | Discussion |
8:10 pm - 8:30 pm | James Olcese (FSU College of Medicine, Tallahassee, FL) "Melatonin Supplementation as a Neuroprotective Strategy in a Transgenic Model of Alzheimer Dementia" |
8:30 pm - 8:40 pm | Discussion |
8:40 pm - 9:00 pm | Beth A. Malow (Vanderbilt University Medical Center, Nashville TN) "Treating Insomnia in Children with Autism Spectrum Disorders: The Promise of Melatonin" |
9:00 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 11:40 am | MELATONIN EFFECTS ON SLEEP AND CIRCADIAN RHYTHMS |
9:00 am - 9:10 am | Discussion Leader: Debra J. Skene (University of Surrey, Guildford, UK) |
9:10 am - 9:30 am | Irina V. Zhdanova (Boston Univ. Med. School, Boston, MA) "What Can Melatonin Do Without the SCN?" |
9:30 am - 9:40 am | Discussion |
9:40 am - 10:00 am | Phyllis C. Zee (Northwestern University, Evanston, IL) "Melatonin, Circadian Rhythms and Sleep in Humans" |
10:00 am - 10:10 am | Discussion |
10:10 am - 10:25 am | Coffee Break |
10:25 am - 10:45 am | Charmane I. Eastman (Rush University Medical Center, Chicago, IL) "Melatonin Phase Response Curves" |
10:45 am - 10:55 am | Discussion |
10:55 am - 11:15 am | Kenneth P. Wright, Jr (University of Colorado, Boulder, CO) "Melatonin, Thermoregulation and Sleep" |
11:15 am - 11:25 am | Discussion |
11:25 am - 11:40 am | General Discussion |
11:40 am - 12:30 pm | HOT TOPICS SESSION #3 |
| (Speakers selected from posters) |
| Discussion Leader: Samer Hattar (Johns Hopkins School of Medicine, Baltimore MD) |
11:40 am - 11:50 am | Steven Hill (Tulane University School of Medicine, New Orleans, LA) "Conditional expression of the MT1 melatonin receptor impedes mammary gland development in mice" |
11:50 am - 11:55 am | Discussion |
11:55 am - 12:05 pm | Rodrigo Lacruz (University of Southern California, Los Angeles, CA) "Hard tissue rhythms: The long and short of it in organismal biology" |
12:05 pm - 12:10 pm | Discussion |
12:10 pm - 12:20 pm | Anastasia Saade (Cochin Institute- Orsay University, Paris, France) "Impact of circadian protein networks on hippocampus plasticity" |
12:20 pm - 12:25 pm | Discussion |
12:25 pm - 12:30 pm | General Discussion |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
7:30 pm - 9:30 pm | WHEN LIGHT INTERRUPTS THE NIGHT: DYING FOR DARKNESS |
| Discussion Leader: George C. Brainard (Thomas Jefferson University, Philadelphia, PA) |
7:30 pm - 7:50 pm | Jennifer A. Evans (Morehouse School of Medicine, Atlanta, GA) "Circadian plasticity is enhanced by dim light at night" |
7:50 pm - 7:55 pm | Discussion |
7:55 pm - 8:15 pm | Alec J. Davidson (Morehouse School of Medicine, Atlanta, GA) "Adverse Health Consequences of Circadian Disruption in Mice" |
8:15 pm - 8:20 pm | Discussion |
8:20 pm - 8:40 pm | Richard G. Stevens (University of Connecticut Health Center, Farmington, CT) "Light at Night, Circadian Disruption, and Breast Cancer" |
8:40 pm - 8:45 pm | Discussion |
8:45 pm - 9:05 pm | Till Roenneberg (Ludwig-Maximilians-University, Munich, Germany) "Light at Night: A Health Risk Factor or a Health Risk Predictor?" |
9:05 pm - 9:10 pm | Discussion |
9:10 pm - 9:30 pm | General Discussion |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Depart |