SUNDAY |
2:00 pm - 9:00 pm | Arrival and check-in |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | DEBATE: DO PRL AND GH CAUSE CANCER? |
| Discussion Leader: Paul A. Kelly (Faculty of Medicine Necker, Paris, France) |
7:30 pm - 9:30 pm | Stephen M Shalet (Christie Hospital, Manchester, UK) and Jeff Holly (Bristol Royal Infirmary, Bristol, UK) |
MONDAY |
7:30 am - 8:30 am | Breakfast |
8:40 am - 8:55 am | Group Photograph |
9:00 am -12:00 pm | MOUSE MODELS, MICROARRAY ANALYSIS & PROTEOMICS |
| Discussion Leader: Arthur Gutierrez-Hartmann (University of Colorado Medical Center, Denver, CO) |
9:00 am - 9:40 am | Martin Hrabé-De Angelis (GSF National Research Center of Environment, Neurherberg, Germany) "Large scale production and characterization of mouse models for inherited diseases in man" |
9:40 am - 10:20 am | Gunnar Norstedt (Karolinska Institute, Stockholm, Sweden) "Microarray analysis of growth hormone regulated gene expression in the rat" |
10:20 am -10:40 am | Coffee Break |
10:40 am-11:20 am | Christopher J. Ormandy (Garvan Institute of Medical Research, Sydney, Australia) "Identification of prolactin responsive genes by microarray analysis" |
11:20 am-12:00 pm | Dominic M. Desiderio (University of Tennessee, Memphis, TN) "Proteomic analysis of the human pituitary" |
12:00 pm-12:30 pm | PLATFORM PRESENTATIONS |
| Discussion Leader: Shlomo Melmed (Cedars Sinai, Los Angeles, CA) |
12:00 pm-12:15 pm | Matthew J. LeBaron (Uniformed Sciences University, Bethesda, MD) "Strategy to identify interaction sites of transcription factor Stat5 within the human genome" |
12:15 pm-12:30 pm | Allan J. Nixon (Ruakuva Research Center, Hamilton, New Zealand) "Expression patterns of prolactin receptor, prolactin, placental lactogen and growth hormone over a hair cycle induced in murine skin" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | PRL AND GH PHYSIOLOGY |
| Discussion Leader: Geula Gibori, (University of Illinois, Chicago, IL) |
7:30 pm - 8:10 pm | David Kleinberg (New York University Medical Center, New York, NY)
"GH and prostate function" |
8:10 pm - 8:50 pm | Olle Isaksson (Sahlgrenska University Hospital, Gothenburg, Sweden) "Physiological significance of endocrine versus locally produced growth factors/hormones in the PRL/GH regulatory system" |
8:50 pm - 9:30 pm | Filipe F. Casanueva (Santiago de Compostela University, Spain) "GH and PRL interactions with the leptin axis" |
TUESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am - 12:00 pm | PITUITARY DEVELOPMENT AND REGULATION |
| Discussion Leader: Nira Ben-Jonathan (University of Cincinnati, OH) |
9:00 am - 9:40 am | Shane Hentges(Oregon Health Sciences University, Portland, OR) "Pituitary lactotroph regulation in D2R-PRLR deficient mice" |
9:40 am - 10:20 am | Priscilla Dannies (Yale University, New Haven, CT) "Sorting of prolactin and growth hormone into secretory granules" |
10:20 am-10:40 am | Coffee Break |
10:40 am-11:20 am | Rula Abbud (Cedars Sinai Research Institute, Los Angeles, CA) "Differential regulation or PRL, GH and POMC by Leukemia Inhibitory Factor (LIF)" |
11:20 am-12:00 pm | Michael O Thorner (University of Virginia School of Medicine, Charlottesville, VA) "GH secretagogues in humans |
12:00 pm-12:30 pm | PLATFORM PRESENTATIONS |
| Discussion Leader: Shlomo Melmed (Cedars Sinai, Los Angeles, CA) |
12:00 pm-12:15 pm | Marcello Bronstein (University of Sao Paulo, Brazil) "Prolactin: it isn't always what it seems" |
12:15 pm-12:30 pm | Sophie Bernichtein (Necker Faculty of Medicine, Paris, France) "Development and importance of new homologous bioassays for human lactogens: which assay for what purpose?" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:30 pm | AGONISTS, ANTAGONISTS AND ASSAYS |
| Discussion Leader: John Kopchick (Ohio University, Athens, OH) |
7:30 pm - 8:10 pm | Vincent Goffin (Faculty of Medicine Necker, Paris, France) "Development and use of prolactin antagonists" |
8:10 pm - 8:50 pm | Peter J. Trainer (Christie Hospital, Manchester, UK) "GH receptor antagonists in man" |
8:50 pm - 9:30 pm | Christian J. Strasburger (Ludwig Maximilians University, Munich, Germany) "GH, placental hormones and PRL assays: state of the art" |
WEDNESDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am -12:00 pm | EFFECTS OF PRL AND GH IN PERIPHERAL TISSUES |
| Discussion Leader: Elisabeth L. Hooghe-Peters (Free University of Brussels, Belgium) |
9:00 am - 9:40 am | Annette Moldrup (Hagedorn Research Institute, Gentofte, Denmark) "Mechanisms of GH- and PRL-induced replication of pancreatic beta-cells" |
9:40 am -10:20 am | Michael Freemark (Duke University School of Medicine, Durham, NC) "Metabolism and weight gain in PRL receptor deficient mice" |
10:20 am-10:40 am | Coffee Break |
10:40 am-11:20 am | Nelson Horseman (University of Cincinnati, Cincinnati, OH) "Prolactin induction of mammary tryptophan hydroxylase expression: mechanisms and physiology" |
11:20 am-11:50 am | PLATFORM PRESENTATIONS |
| Discussion Leader: Shlomo Melmed (Cedars Sinai, Los Angeles, CA) |
11:20 am-11:35 am | Karen Liby (University of Cincinnati, Cincinnati, OH) "Prolactin as a local growth/anti-apoptotic factor in MDA-MB-435 breast cancer cells" |
11:35 am-11:50 am | Sok-Hyong Lee (Baylor College of Medicine, Houston, TX) "Anti-inflammatory effects of estrogen and prolactin during hemorrhagic shock" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 8:00 pm | Business Meeting |
8:00 pm - 9:30 pm | BEHAVIOR AND LIFESTYLES |
| Discussion Leader: Susan Berry (University of Minnesota, Minneapolis, MN) |
8:00 pm - 8:45 pm | Luz Torner (Regensburg University, Regensburg, Germany) "Anxiolytic and anti-stress effects of brain prolactin" |
8:45 pm - 9:30 pm | Steven Lamberts (University Hospital Dijkzigt, Rotterdam, Netherlands) "The role of IGF-I in frailty and lifestyles" |
THURSDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am -12:00 pm | PRL and GH Signaling |
| Discussion Leader: Linda Schuler (University of Wisconsin, Madison, WI)
|
9:00 am -9:40 am | Li Yu-Lee (Baylor College of Medicine, Houston, TX) "Prolactin and activation of interferon regulated factor-1 gene transcription" |
9:40 am -10:20 am | Suhad Ali (McGill University, Montreal, Canada) "Phosphatases and prolactin signaling" |
10:20 am-10:40 am | Coffee Break |
10:40 am-11:20 am | Charles V. Clevenger (University of Pennsylvania, Philadelphia, PA) "The importance of nuclear prolactin in signal transduction" |
11:20 am-12:00 pm | David R. Clemmons (University of North Carolina, Chapel Hill, NC) "Cellular context determines GH and IGF-I receptor responsiveness" |
12:00 pm-12:30 pm | PLATFORM PRESENTATIONS |
| Discussion Leader: Shlomo Melmed (Cedars Sinai, Los Angeles, CA) |
12:00 pm-12:15 pm | Monica M. Richert (University of Colorado Health Sciences Center, Denver, CO) "Deletion of downstream effectors of PRLR signaling affect mouse mammary gland development" |
12:15 pm-12:30 pm | Charlotte A. Ling (Goteborg University, Goteborg, Sweden) "PRL mediated effects in adipocytes" |
12:30 pm | Lunch |
1:30 pm - 4:00 pm | Free Time |
4:00 pm - 6:00 pm | Poster Session |
6:00 pm | Dinner |
7:30 pm - 9:00 pm | KEYNOTE ADDRESS |
| Discussion Leader: Shlomo Melmed (Cedars Sinai Research Institute, Los Angeles, CA) |
7:30 pm - 9:00 pm | Michael Geoff Rosenfeld (University of California at San Diego, CA) "Genetic control of pituitary development" |
FRIDAY |
7:30 am - 8:30 am | Breakfast |
9:00 am | Departure |