Sunday, July 1, 2001 |
5:00-6:00 PM | Reception |
6:00 PM | Dinner |
| Evening Session: Welcome and Opening Remarks |
7:30 PM | C. D. Garner (Nottingham University, Nottingham, UK) & R. R. Mendel (Technical University of Braunschweig, Braunschweig, Germany) |
8.00-8.45 PM | R. J. P. Williams (University of Oxford, Oxford, UK) "The Evolution of Inorganic Species in Biology" |
Monday, July 2, 2001 |
7:45-8:30 AM | Breakfast |
| Morning Session: Crystallography and Mechanistic Enzymology |
8:45 AM | R. Hille (Ohio State University, Columbus, Ohio, USA), Discussion Leader "Opening Remarks" |
9:00 AM | H. Dobbek (Max-Planck-Institut für Biochemie, Martinsried, Germany) "Molybdenum and Tungsten Enzymes: A Crystallographic Perspective" |
9:45 AM | E. F. Pai (University of Toronto, Toronto, Ontario, Canada) "Structural Characterization of the transition from Xanthine Dehydrogenase to Xanthine Oxidase" |
10:30 AM | Break |
11:00 AM | J. M. Santini (La Trobe University, Melbourne, Victoria, Australia) "Mechanisms of Arsenic and Selenium Metabolism Involving Different Molybdenum-containing Enzymes" |
11:45 AM | W. H. Campbell (Michigan Technical University, Houghton, Michigan, USA) "Kinetics and Mechanism of Eukaryotic NAD(P)H: Nitrate Reductase" |
12:45 PM | Group Photograph / Lunch |
6:00 PM | Dinner |
| Evening Session: Biochemistry of Molybdenum and Tungsten |
7:30 PM | E. I. Stiefel (ExxonMobil Research and Engineering, Annandale, New Jersey, USA), Discussion Leader "Opening Remarks" |
7:45 PM | K. T. Shanmugam (University of Florida, Gainesville, Florida, USA) "Molybdenum Metabolism" |
8:30-9:15 PM | D. H. Boxer (University of Dundee, Dundee, UK) "Regulation by Molybdenum and Tungsten" |
Tuesday, July 3, 2001 |
7:45-8:30 AM | Breakfast |
| Morning Session: Molybdenum Cofactor - Synthesis and Biosynthesis |
8:45 AM | B. Fischer (Ruhr-Universität Bochum, Bochum, Germany), Discussion Leader "Opening Remarks" |
9:00 AM | K. V. Rajagopalan (Duke University Medical Center, Durham, North Carolina, USA ) "The Molybdenum Cofactor, its Nature, and Biological Roles" |
9.45 AM | A. Dinsmore (University of Witwatersrand, Johannesburg, South Africa) "Towards the Chemical Synthesis of Molybdopterin" |
10:30 AM | Break |
11:00 AM | G. Schwarz (Technical University of Braunschweig, Braunschweig, Germany) "Molybdenum Cofactor Biosynthesis in Humans and Plants" |
11:45 AM | H. Schindelin (SUNY, Stony Brook, New York, USA) "Structural Studies of Enzymes Involved in Molybdenum Cofactor Biosynthesis" |
12:45 PM | Lunch |
6.00 PM | Dinner |
| Evening Session: Bioinspired Co-ordination Chemistry |
7:30 PM | C. G. Young (University of Melbourne, Melbourne, Australia), Discussion Leader "Opening Remarks" |
7:45 PM | S. Burgmayer (Bryn Mawr College, Bryn Mawr, Pennsylvania, USA) "Molybdenum Dithiolene Model Chemistry" |
8:05 PM | Kie-Moon Sung (Harvard University, Cambridge, Massachusetts, USA) "New Generation of Active Site Analogues of Molybdenum and Tungsten Enzymes" |
8:25 PM | P. Basu (Duquesne University, Pittsburgh, Pennsylvania, USA) "Encapsulated Molybdenum Centers: Implications for Mononuclear Molybdenum Enzymes" |
8:45 PM | J. McMaster (Nottingham University, Nottingham, UK) "Pre-edge X-ray Absorption Spectra of Oxomolybdenum Complexes: Implications for Sulfite Oxidase" |
9:05-9:50 PM | M. L. Kirk (University of New Mexico, Albuquerque, New Mexico, USA) "Electronic Structure Contributions to Reactivity in Xanthine Oxidase" |
Wednesday, July 4, 2001 |
7:45-8:30 AM | Breakfast |
| Morning Session: Molybdenum and Tungsten Enzymes - Transport and Function |
8:45 AM | R. Thauer (Max-Planck-Institut für Terrestriche Mikrobiologie, Marburg, Germany), Discussion Leader "Opening Remarks" |
9:00 AM | T. Palmer (John Innes Centre, University of East Anglia, Norwich, UK) " A Novel Pathway for the Export of Bacterial Periplasmic Molybdenum Enzymes" |
9:45 AM | M. W. W. Adams (University of Georgia, Athens, Georgia, USA) "Molybdenum and Tungsten Proteins in Hyperthermophiles" |
10:30 AM | Break |
11:00 AM | P. M. H. Kroneck (University of Konstanz, Konstanz, Germany) "Molybdopterin-dependent Enzymes that Catalyse Non-redox Reactions" |
11:45 AM | A. G. McEwan (University of Queensland, Queensland, Australia) "Dimethylsulfide dehydrogenase - its place in the DMSO Reductase Family of Molybdopterin Enzymes" |
12:45 PM | Lunch |
5:00 PM | Business Meeting |
6:00 PM | Dinner |
| Evening Session: Pterins: Medical and Agricultural Significance of Molybdenum Enzymes |
7:30 PM | E. Garattini (Instituto de Ricerche Farmacologiche, Milan, Italy), Discussion Leader "Opening Remarks" |
7:45 PM | W. Pfleiderer (University of Konstanz, Konstanz, Germany) "From Butterfly Pigments to Molybdopterin" |
8:30 PM | T. Nishino (Nippon Medical School, Tokyo, Japan) "Medical Aspects of Xanthine Dehydrogenase and Oxidase" |
9.15-10:00PM | S. H. Lips (Blaustein Institute for Desert Research, Gurion University, Sede Boquer, Israel) "Molybdenum Enzymes, Inorganic Nitrogen Ions, and Plant Growth Regulation". |
Thursday, July 5, 2001 |
7:45-8:30 AM | Breakfast |
| Morning Session: Characterisation of Molybdenum and Tungsten Enzymes by Physical Methods |
8:45 AM | M. W. Johnson (University of Athens, Georgia, USA), Discussion Leader "Opening Remarks" |
9:00 AM | M. J. Romão (Universidade Nova de Lisboa, Caparica, Portugal) "Crystal Structure of Formate Dehydrogenase from Desulfovibrio gigas: A Tungsten Enzyme containing Se and Four 4Fe-4S Centers" |
9:45 AM | J. Butt (University of East Anglia, Norwich, UK) "Voltammetric Studies of Nitrate Reductases" |
10:30 AM | Break |
11:00 AM | R. C. Bray (University of Sussex, Brighton, UK) "Recent findings on dimethylsulfoxide reductase from UV/visable spectroscopy and X-ray crystallography" |
11:45 AM | J. H. Enemark (University of Arizona, Tucson, Arizona, USA) "Studies of Sulfite Oxidase by Variable Frequency Multi-pulse EPR Spectroscopy" |
12:45 PM | Lunch |
6:00 PM | Banquet |
| Final Session - Round Table |
7:30-9:30 PM | Future directions for the field; industrial and medical applications of the knowledge base. |
Friday, July 6, 2001 |
7:30-8:30 AM | Breakfast |