Gordon Research Conferences
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Conference Program
 
Spirochetes, Biology of
January 18-23, 1998
Crowne Plaza
Ventura, CA

Sunday Evening, January 18 (7:30-9:30)
Evolution and Genetics
Discussion Leader--Guy Baranton

Ulf Göbel

Diversity and ecology of novel and uncultured treponemes from chronic mixed infections in man and cattle

John Breznak

Biology and phylogeny of termite gut spirochetes

Thad Stanton

VSH-1, an unusual bacteriophage of Serpulina hyodysenteriae

David Persing

Genetic diversity of B. burgdorferi in the United States: A prelude to premunition?

Monday Morning, January 19 (9:00-12:30)
Gene Organization, Expression, and Function
Discussion Leader--Masahito Fukunaga

Tom Schwan

Common themes in protein regulation in the genus Borrelia

Frank Gherardini

Metal requirements of Borrelia burgdorferi

David Nelson

Spirochetes and spit

Russ Johnson

Borrelia burgdorferi: plasmids and infectivity

Howard Kuramitsu

Identification of virulence factors for oral spirochetes

Monday Evening, January 19 (7:30-9:30)
Prospecting the Genomes of Spirochetes--Where do we go from here?
Discussion Leader--Mike Norgard

Sherwood Casjens

The B. burgdorferi chromosome and plasmids: sequences, genes, and universality.

Rich Zuerner

Genetic organization and rearrangement in Leptospira

George Weinstock

The genome of Treponema pallidum

Tuesday Morning, January 20 (9:00-12:30)
Host-Parasite Interactions
Discussion Leader--Richard Ellen

Stephen Barthold

Immunological relevance of B. burgdorferi antigens expressed during infection of the mammalian host

Pam Pennington

Genetics and structure of Vsp/OspC Proteins of Borrelia

Jorge Benach

Fibrinolytic system requirements for B. burgdorferi invasion

Isabelle Saint-Girons

Intracellular location of virulent Leptospira: Protective effects of eucaryotic cells against the action of penicillin

Richard Ellen

How T. denticola sheath proteins perturb the cytoskeleton of cultured cells

Tuesday Evening, January 20 (7:30-9:30)
Spirochete Membrane Antigens
Discussion Leader--Alan Barbour

Chris Fenno

The major surface protein (Msp) of Treponema denticola and related organisms

David Blanco

Tromp 1 and 2 are outer membrane proteins of T. pallidum

Justin Radolf

The quest for spirochetal rare outer membrane proteins: A reappraisal

Wednesday Morning, January 21 (9:00-12:30)
Mechanisms of Pathogenesis
Discussion Leader--Sven Bergstrom

Graciela Rosen

The major phenylalanine proteinase of T. denticola

Sally Cutler

B. recurrentis: Perspectives on persistance and antigenic variation

Jing-Ren Zhang

Genetic and antigenic variation of B. burgdorferi lipoprotein VlsE

Arturo Centurion

Identification of a polymorphic, multicopy gene family in pathogenic treponemes

Wednesday Evening, January 21 (7:30-9:30)
Biology and Ecology
Discussion Leader--Ulrike Munderloh

Paul Kolenbrander

Bacterial interactions and the ecology of oral biofilms

David Hampson

Serpulina pilosicoli: Population genetics, pathogenesis and control

Ron Limberger

Determining the role of cytoplasmic filaments and the unique aqueous protein Tap1 in treponemal motility

Lola Stamm

Spirochetal motility and chemotaxis genes

Thursday Morning, January 22 (9:00-12:30)
Antigens and Host Responses
Discussion Leader--Janis Weis

Michael Norgard

Structure-function relationships for T. pallidum lipoproteins

Linda Bockenstedt

Role of specific immunity in murine Lyme borreliosis

Reinhard Straubinger

Immune and cytokine response to Borrelia burgdorferi during acute Lyme arthritis in the dog model

Barbara Johnson

Characterization of the cartilage proteoglycan (aggrecan) binding activity of Borrelia burgdorferi

Bettina Wilske

Antigenic heterogeneity in B. burgdorferi strains from Europe

Markus Simon

Strategies for Lyme disease vaccination

Thursday Evening, January 22 (7:30-9:30)
Discussion Leader--Sheila Lukehart

Business meeting

Overview


 
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