Gordon Research Conferences
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Conference Program
 
Tetrapyrroles, Chemistry & Biology of
July 14-19, 2002
Salve Regina University
Newport, RI
Chair:
Gloria C. Ferreira

Vice Chair:
Mark R. O'Brian

Contributors
The National Institutes of Health
The National Science Foundation
United States Department of Agriculture
University of South Florida, Sponsored Research Office
Yamanouchi USA Foundation
University of South Florida, College of Medicine
The Porphyria Foundation
Frontier Scientific, Inc.
NOVARTIS Pharmaceuticals Corp.
On-Line Instrument Systems, Inc.

SUNDAY
2:00 pm - 9:00 pmArrival and check-in
6:00 pmDinner
7:30 pm - 9:30 pmEMERGING TECHNOLOGIES: GENOMICS AND BEYOND
Discussion Leader: Mark O'Brian (State Univ. New York at Buffalo)
7:30 pm - 8:30 pmPeter H. Quail (University of California, Berkeley)
"Phytochrome Signaling Networks"
8:30 pm - 9:30 pmClaudia Schmidt-Dannert (University of Minnesota)
“Creation of New Biosynthetic Pathways using Directed Evolution and Combinatorial Strategies”
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmENZYMOLOGY OF TETRAPYRROLE BIOSYNTHESIS
Discussion Leader: Martin Warren (Queen Mary, University of London)
9:00 am - 10:00 amOsamu Nakajima (Yamagata University, Japan)
"In Vivo Analysis of Erythroid-specific Aminolevulinate Synthase Function"
9:45Group Photo
10:00 amCoffee Break
10:30 am - 11:30 amEileen Jaffe (Fox Chase Cancer Center, Philadelphia)
"Porphobilinogen Synthase or ALAD, Whatever You Call It, It's a Fascinating Family of Enzymes"
11:30 am - 12:30 pmDieter Jahn (Technical University Braunschweig, Germany)
"Glutamyl-tRNA Reductase and Coproporphyrinogen III Oxidases: Enzymatic Mechanisms and Their Structural Basis"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmSUPRAMOLECULAR AND DYNAMIC COMBINATORIAL CHEMISTRY
Discussion Leader: Kevin Smith (Louisiana State University)
7:30 pm - 8:30 pmJeremy K. M. Sanders (Cambridge University, UK)
"Porphyrins and Dynamic Combinatorial Libraries"
8:30 pm - 9:30 pmJonathan L. Sessler (University of Texas at Austin)
"Synthesis and Applications of Novel Polypyrrole Macrocycles"
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIRON TRANSPORT AND METAL REGULATION OF TETRAPYRROLE METABOLISM
Discussion Leader: Ann Smith (University of Missouri)
9:00 am - 10:00 amSabeeha Merchant (UCLA)
"Copper-nutrition dependent Synthesis and Function of Chlorophyll Proteins"
10:00 amCoffee Break
10:30 am - 11:30 amRoland Lill (Universität Marburg, Germany)
"Iron Transport and Maturation of Cellular Fe-S Proteins"
11:30 am - 12:30 pmCecile Wandersman (Institute Pasteur, France)
"Structure and Function of Bacterial Hemophores"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pm Dinner
7:30 pm - 9:30 pmPLANT TETRAPYRROLES
Discussion Leader: Bernhard Grimm (Humboldt University, Berlin, Germany)
7:30 pm - 8:30 pmKlaus Apel (Swiss Federal Institute of Technology Zürich, Switzerland)
"A Genetic Approach Towards Understanding the Control of Tetrapyrrole Biosynthesis"
8:30 pm - 9:30 pmJoanne Chory (The Salk Institute)
"The Role of Tetrapyrroles in Intracellular Signaling from the Chloroplast to the Nucleus in Plants"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNOVEL FACETS OF HEME
Discussion Leader: Paul R. Ortiz de Montellano (University of California, San Francisco)
9:00 am - 10:00 amPeter Kroneck (University of Konstanz, Germany)
"Multiheme Proteins and Enzymes: From Structure to Electron Transfer to Reaction Mechanism"
10:00 amCoffee Break
10:30 am - 11:30 amKenton Rodgers (North Dakota State University)
"Recent Insights into the Signal transduction Mechanism of the O2-sensing Protein FixL"
11:30 am - 12:30 pmMichael Marletta (University of California, Berkeley)
"Guanylate Cyclase and NO Signaling"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmTETRAPYRROLE CATABOLISM: LINEAR TETRAPYRROLES AND SIGNALING MECHANISMS
Discussion Leader: Tony McDonagh (University of California, San Francisco) and Tadashi Yoshida (Yamagata University)
7:30 pm - 8:30 pmTadashi Yoshida (Yamagata University, Japan)
"10-min overview on Biliverdin Reductase"
7:30 pm - 8:30 pmTimothy J. Mantle (Trinity College, Ireland)
"The Enzymology of Biliverdin Reduction"
8:30 pm - 9:30 pmNicole Frankenberg (University of California, Davis)
"Bilin Reductases in Plants and Cyanobacteria"
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmHEME-MEDIATED SIGNAL TRANSDUCTION AND CLINICAL IMPLICATIONS
Discussion Leader: James Kushner (University of Utah)
9:00 am - 10:00 amJane-Jane Chen (Harvard-MIT Div. Health Sciences and Technology)
"Heme-regulated eIF2a Kinase: Translational Control and Beyond "
10:00 amCoffee Break
10:30 am - 11:30 amMitchell Weiss (Children's Hospital of Philadelphia)
"New Insights into Hemoglobin Biology"
11:30 am - 12:30 pmMax Gassmann (University of Zurich, Switzerland)
"Oxygen-dependent and independent Erythropoietin Gene Expression: Coping with a Hematocrit of 80-90%"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
5:00 pm - 6:00 pmPoster Session with Presenters
6:00 pmDinner
7:30 pm - 9:30 pmBUSINESS MEETING AND KEYNOTE ADDRESS (ALEXANDER M. CRUICKSHANK LECTURE)
7:30 pm - 8:15 pmBusiness Meeting
8:15 pm - 9:30 pmKeynote Address
Discussion Leader: Gloria C. Ferreira (University of South Florida)
Greg Petsko, 2002 A. M. Cruickshank Lecturer (Brandeis University)
"The Origin of Enzymatic Species"
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

 
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