| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | New Paradigms For Molecular Detection |
| 7:30 pm - 7:40 pm | Discussion Leader: Peter Greenwald, M.D., Dr.PH.
National Cancer Institute |
| 7:40 pm - 8:10 pm | David Sidransky, M.D., Johns Hopkins University
Molecular Screening and Detection |
| 8:10 pm - 8:40 pm | Joe Gray, Ph.D. , University of California San Francisco
Genomic Events in Low Grade and Stage Breast and Ovarian Cancer as Early Detection Markers |
| 8:40 pm - 9:10 pm | Richard Smith, Ph.D., Pacific Northwest National Laboratory
New Proteome Analysis Technologies for Cancer Research |
| 9:10 pm - 9:30 pm | Discussant |
| Reception to follow |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 12:30 pm | Molecular Profiling for Cancer Detection and Cancer Risk Identification |
| 9:00 am - 9:20 am | Discussion Leader: Anne-Lise Borresen-Dale, Oslo |
| 9:20 am - 10:00 am | Todd Golub, Ph.D., Massachusetts Institute of Technology
Genomic Information and Cancer |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Steve Meltzer, M.D.
Analytic Approach to Genomic Data |
| 11:00 am - 11:30 am | Bruce Ponder, Ph.D. Cambridge University, UK
The Prospects for SNP-Based Risk Profiles for Breast Cancer |
| 11:30 am - 12:00 pm | Nancy Kiviat, M.D., Ph.D., University of Washington
Molecular Markers for Cancer Screening: Promise and Potential Problems |
| 12:00 pm - 12:10 pm | Poster Presenter: Michael Barrett, Agilent Laboratories |
| 12:10 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Cancer Cell Detection Strategies |
| 7:30 pm - 7:40 pm | Discussion Leader: Jeffrey Marks, Duke University |
| 7:40 pm - 8:10 pm | Richard Cote, M.D. University of Southern California
Occult Cancer Cells |
| 8:10 pm - 8:40 pm | Bogdan Cerniak, M.D., University of Texas MD Anderson
Genomic and Cytologic Approaches to Bladder Cancer Detection |
| 8:40 pm - 9:10 pm | Jose Costa, M.D., Yale School of Medicine
Mutational load in early detection |
| 9:10 pm - 9:20 pm | Poster Presenter: Bonnie L. King, Yale University School of Medicine |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Promises and Challenges In Application of Proteomic Approaches for Cancer Detection |
| 9:00 am - 9:20 am | Discussion Leader: Emanuel Petricoin, Ph.D., FDA |
| 9:20 am - 10:00 am | Lance Liotta, M.D., National Cancer Institute
Proteomic Pattern Diagnostics: Moving Towards the Bedside |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:10 am | John Semmes, Ph.D., Eastern Virginia Medical School
Protein Profiling and Early Detection of Cancer: Progress made and hurdles to overcome |
| 11:10 am - 11:40 am | Julio Celis, Ph.D., Danish Center for Human Genome Research
Proteomics and Functional Genomics in Translational Breast Cancer Research |
| 11:40 am - 11:50 am | Poster Presenter: Bin Ye, Brigham and Women's Hospital |
| 11:50 am - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #2 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Promises and Challenges of Epigenomic in Cancer Detection |
| 7:30 pm - 7:40 pm | Discussion Leader: James Herman, M.D., Johns Hopkins University |
| 7:40 pm - 8:10 pm | Peter Laird, Ph.D., University of Southern California
Epigenetics Alterations In Esophageal Cancer (tentative) |
| 8:10 pm - 8:40 pm | Adi Gazdar, M.D., University of Texas Southwestern Medical School
Hypermethylation in Lung Carcinoma (tentative) |
| 8:40 pm - 9:10 pm | David Botstein, Ph.D., Stanford University
Genome-Wide Patterns of Gene Expression in Cancer |
| 9:10 pm - 9:20 pm | Poster Presenter: Brian Vuillemenot, Lovelace Respiratory Research Institute |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Models and Tools for Cancer Detection |
| 9:00 am - 9:20 am | Discussion Leader: Robert Strausberg, Ph.D., The
Institute for Genomic Research |
| 9:20 am - 10:00 am | Coffee Break |
| 10:30 am - 11:00 am | Andrew Simpson, Ph.D., Ludwig Institute
Sequence-based Definition of Cancer Transcriptomes As A Route to the Identification of Therapeutic Targets |
| 11:00 am - 11:30 am | Greg Riggins, Ph.D., Duke University
Hunting for Cancer-Specific Gene Expression with SAGE Genie |
| 11:30 am - 12:00 pm | Frank Diehl, Ph.D., Johns Hopkins University
Non-Invasive Tests for the Detection of Colorectal Tumor Using Fecal DNA |
| 12:00 pm - 12:20 pm | Kornelia Polyak, M.D., Ph.D., Harvard Medical School
DCIS Markers for Early Brest Cancer Diagnosis |
| 12:20 pm - 12:30 pm | Poster Presenter: Nam Kim, DIADEXUS |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #3 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Novel Approaches to Biomarker Validation |
| 7:30 pm - 7:40 pm | Discussion Leader: William Bigbee, Ph.D., University of Pittsburgh |
| 7:40 pm - 8:00 pm | Curt Harris, M.D., National Cancer Institute
p53: At the Crossroads of Cancer Detection and Diagnosis |
| 8:00 pm - 8:20 pm | Steve Belinsky, Ph.D., Lovelace Respiratory Research Institute
Gene Targets for Methylation in Lung Cancer: Utility for Predicting Risk |
| 8:20 pm - 8:40 pm | Claudia Henschke, M.D., Cornell University
Identification and Characterization of Cancer Biomarkers in the Context of CT Screening |
| 8:40 pm - 9:00 pm | Barnett S. Kramer, M.D., National Institutes of Health
Validation Study Designs |
| 9:00 pm - 9:20 pm | Nazneen Rehman, Ph.D., Institute of Cancer Research, UK
Low Penetrance Breast Cancer Susceptibility Alleles: Identification, Characterization and Clinical Study |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Computational Tools for the Analysis of Cancer Signatures |
| 9:00 am - 9:20 am | Discussion Leader: John Weinstein, M.D., National Cancer Institute |
| 9:20 am - 10:00 am | Pablo Tamayo, Ph.D., Whitehead Institute of Genomics
Gene Set Enrichment Analysis of Molecular Markers |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Ken Buetow, Ph.D., National Cancer Institute
Interpreting Cancer Signatures Through the Lens of Biological Pathways and Process |
| 11:00 am - 11:30 am | Sam Hanash, M.D., University of Michigan
Computational Tools for Integrated Genomic and Proteomic Profiles |
| 11:30 am - 11:50 am | Yutaka Yasui, Fred Hutchinson Cancer Center
Data analytic strategies for proteomic biomarker discovery from complex high-dimensional SELDI/MALDI-TOF output |
| 11:50 am - 12:00 pm | Poster Presenter: Hiroyuki Aburtani, University of Tokyo |
| 12:00 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #4 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Molecular Diagnosis: From Bench to the Bedside |
| 7:30 pm - 7:40 pm | Discussion Leader: Gordon Mills, M.D., M.D.
Anderson Cancer Center |
| 7:40 pm - 8:10 pm | Ian Jacob, M.D., St. Bartholomew's & Royal London School of Medicine and Dentistry
Progress and Challenges In Screening for early Detection of Ovarian Cancer |
| 8:10 pm - 8:40 pm | Eleftherios Diamandis, M.D., Mt. Sinai Hospital
Cancer Biomarkers: From Discovery to Clinical Practice - Kallikriens as an Example |
| 8:40 pm - 9:00 pm | David Fishman, M.D., Northwestern School of Medicine
The Tumor Microenvironment: Key to Early Detection |
| 9:00 pm - 9:20 pm | Mauro Ferrari, Ohio State University
Nanotechnology as A Tool Box for Early Detection |
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |