Gordon Research Conferences
PI_Conferences PI_Conferences_Past
Conference Program
 
Ligand Recognition & Molecular Gating
February 29 - March 5, 2004
Crowne Plaza
Ventura, CA
Chair:
Dennis A. Dougherty

Vice Chair:
Benjamin Kaupp

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 9:30 pmKEYNOTE LECTURE
Discussion Leader: Doug Rees (Caltech)
7:30 pm - 8:30 pmRon Kaback (UCLA)
"Structure and Mechanism of Lactose Permease"
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmVOLTAGE SENSING IN ION CHANNELS
9:00 am - 9:40 amDoug Rees (Caltech)
"Crystal Structures of Prokaryotic Mechanosensitive Channels"
9:40 am - 10:00 amEduardo Perozo (Viginia)
"Structural Dynamics of the KvAP voltage-dependent potassium channel in a lipid bilayer"
10:00 amConference Photo / Coffee Break
10:30 am - 11:10 amPancho Bezanilla (UCLA)
"Structure Function in Voltage Dependent Ionic Channels"
11:10 am - 11:50 amDiane Papazian (UCLA)
"Voltage-dependent gating in potassium channels"
11:50 am - 12:30 pmBob Guy (NIH)
"Helical Screw models of voltage gating developed from the KvAP crystal structures"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 8:20 pmACTIVE TRANSPORTERS
7:30 pm - 7:55 pmGeoff Chang (Scripps)
"Structure of Multidrug Resistance Transporters"
7:55 pm - 8:20 pmDa-Neng Wang (NYU)
"Crystal structure and mechanism of the glycerol-3-phosphate transporter of E. coli."
8:20 pm - 9:30 pmRHODOPSIN AND RELATED STRUCTURES
8:20 am - 8:55 pmGebhard Schertler (MRC)
"Light induced states of rhodopsin in 2D and 3D crystals"
8:55 am - 9:30 pmArlene Albert (U. Conn.)
"Activation of the GPCR Rhodopsin"
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSELECTIVITY IN TRANSPORTERS
9:00 am - 9:40 amBob Stroud (UCSF)
"Selectivity and gating among the aquaporin family"
9:40 am - 10:00 amChris Tate (MRC, Cambridge)
"Architecture and oligomeric state of the bacterial multidrug transporter EmrE"
10:00 amCoffee Break
10:30 am - 11:10 amHelmut Grubmüller (Max Plank; Göttingen)
"Molecular mechanisms of aquaporins and F1 ATP synthase studied by protein dynamics simulations"
11:10 am - 11:50 amSusan Buchanan (NIH)
"Structural evidence for iron-free citrate and ferric citrate binding to the TonB-dependent outer membrane transporter FecA"
11:50 am - 12:30 pmMike Wiener (Virginia)
"The outer membrane cobalamin transporter BtuB: structural analysis and mechanistic implications"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmHCN and OTHER K+ CHANNELS
Discussion Leader: Benjamin Kaupp (Jülich)
7:30 pm - 8:10 pmKlaus Benndorf (Jena)
"Gating of CNGA1 and CNGA2 channels studied by flash photolysis"
8:10 pm - 8:50 pmGary Yellen (Harvard)
"Inactivation and coupling in HCN pacemaker channels"
8:50 pm - 9:30 pmAdrien Gross (Northwestern)
"Potassium channel gating observed with site-directed mass tagging"
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmRECOGNITION in LIGAND-GATED ION CHANNELS
9:00 am - 9:40 amTitia Sixma (Netherlands Cancer Institute)
"Insights in nicotinic receptor ligand-binding through AChBP crystal structures"
9:40 am - 10:00 amGabriela Popescu (SUNY, Buffalo)
"Kinetics of binding to NMDA receptors: learning from single channels"
10:00 amCoffee Break
10:30 am - 11:10 amJames Trudell (Stanford)
"Molecular modeling of ligand gated ion channels: comparison with experimental results"
11:10 am - 11:50 amCynthia Czajkowski (Wisconsin)
"GABA-A Receptors: Structural Determinants of Ligand Recognition and Allosteric Cross-talk"
11:50 am - 12:30 pmJonathan Cohen (Harvard)
"Photolabeling of Nicotinic and GABA-A Receptors"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmHERG/CHANNEL BLOCKERS
7:30 pm - 8:10 pmMike Sanguinetti (Utah)
"Structural basis of HERG channel block: a common cause of drug-induced long QT syndrome"
8:10 pm - 8:50 pmBill Catterall (Washington)
"Mapping the Inner Pore and Drug Binding Sites of Voltage-gated Sodium Channels"
8:50 pm - 9:30 pmGreg Kaczorowski (Merck)
"Interactions of small molecules with potassium channels"
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNEW PROBES OF RECEPTOR BINDING and GATING
9:00 am - 9:40 amHenry Lester (Caltech)
"Fluorescence studies on nicotinic receptors"
9:40 am - 10:00 amAdam Weinglass (UCLA)
"Exploiting mass spectrometry to probe substrate binding sites in membrane transport proteins?"
10:00 amCoffee Break
10:30 am - 11:10 amHorst Vogel (Lausanne)
"Ligand-receptor interactions by single molecule technologies"
11:10 am - 11:50 amAnn McDermott (Columbia)
"Structural and Dynamic Studies of Membrane Associated Proteins: High Resolution Solid State NMR"
11:50 am - 12:30 pmAndreas Engel (Basel)
"Assessing membrane protein structure and dynamics with electron and atomic force microscopy"
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmGPCR
7:30 pm - 8:10 pmThue Schwartz (Copenhagen)
"Agonist versus antagonist recognition and gating in 7TM receptors"
8:10 pm - 8:50 pmJennifer Whistler (UCSF)
"RAVE trafficking and addiction: a GPCR's journey"
8:50 pm - 9:30 pmMichel Bouvier (Montreal)
"Assembly of G Protein-Coupled Receptor Signaling Complexes"
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

 
© 2014 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter