| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and check-in |
| 5:00 pm | Chair's reception in hotel |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | COMPARATIVE GENOMICS |
| Discussion Leader: Sherwood Casjens (University of Utah, SLC UT) |
| 7:30 pm - 8:15 pm | Claire Fraser (The Institute for Genomic Research, Rockville, MD)
"Comparative Genomics of Pathogenic Bacteria, including Spirochetes" |
| 8:15 pm - 8:45 pm | Rich Zuerner (USDA, Ames, IA)
"Genome structure and organization of Leptospira " |
| 8:45 pm - 9:15 pm | Tom Schwan (NIAID, Rocky Mountain laboratories, Hamilton, MT)
"Comparative genomics of relapsing fever and Lyme disease spirochetes" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | SPIROCHETE BIOLOGY & DIVERSITY |
| Discussion Leader: Nyles Charon (West Virginia Univ, Morgantown, WV) |
| 9:00 am - 9:30 am | Daniel Dykhuizen (SUNY, Stony Brook, NY)
"Frequencies of OspC clones of Borrelia burgdorferi are determined by densities of host species" |
| 9:30 am - 10:15 am | Roberto Kolter (Harvard Medical School, Harvard, MA)
"Microbial Communities" |
| 10:15 am - 10:45 am | Lola Stamm (UNC at Chapel Hill, NC)
"Treponema involvement in papillomatous digital dermatitis of cattle" |
| 10:45 am - 11:25 am | Coffee Break / Photo |
| 11:25 am - 11:55 am | Bruce Paster (Forsyth Institute, Boston MA)
"Diversity of oral Treponemes" |
| 11:55 am - 12:25 pm | Jared Leadbetter (California Institute of Technology, Pasadena, CA)
"Spirochete symbionts of termites" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | GENETICS/GENETIC MANIPULATION |
| Discussion Leader: Isabelle Saint Girons (Institut Pasteur, Paris, France) |
| 7:30 pm - 8:00 pm | Patti Rosa (NIAID, Rocky Mountain labs, Hamilton, MT)
"Identification of host-specific gene requirements in B. burgdorferi" |
| 8:00 pm - 8:30 pm | Steve Norris (UT Houston Medical School, Houston, TX)
"Genetic analysis of pathogenesis in B. burgdorferi" |
| 8:30 pm - 9:00 pm | Howard Kuramitsu (SUNY at Buffalo, NY)
"Genetic analysis of biofilm formation by Treponema denticola" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | HOST DEFENSE |
| Discussion Leader: Linda Bockenstedt (Yale University School of Medicine, New Haven CT) |
| 9:00 am - 9:30 am | Ruth Montgomery (Yale University School of Medicine, New Haven CT)
"Phagocyte killing of B. burgdorferi" |
| 9:30 am - 10:00 am | Sean Connolly (SUNY, Stony Brook, NY)
"Host defense to the relapsing fever spirochetes" |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Seppo Meri (University of Helsinki, Finland)
"Strategies for complement evasion by B. burgdorferi" |
| 11:00 am - 11:30 am | Aravinda de Silva (UNC, Chapel Hill, NC)
"Mechanisms of Borrelia burgdorferi transmission from ticks to hosts" |
| 11:30 am - 12:00 pm | Lise Gern (U of Neuchatel, Switzerland)
"Borrelia burgdorferi sensu lato and Ixodes ricinus: their relationships" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session I |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | IMMUNE RECOGNITION & ANTIGENS |
| Discussion Leader: Bettina Wilske (Univ Munich, Munich Germany) |
| 7:30 pm - 8:00 pm | Erol Fikrig (Yale University School of Medicine, New Haven, CT)
"OspC facilitates spirochete transmission within ticks" |
| 8:00 pm - 8:30 pm | Ivo Francischetti (Laboratory of Parasitic Diseases, NIAID, NIH)
"Insights from the sialome of Ixodes scapularis" |
| 8:30 pm - 9:00 pm | David Blanco (UCLA School of Medicine, Los Angeles, CA)
"Identification of a novel Treponema pallidum surface antigen that is a target of killing antibody and protective immunity" |
| 9:00 pm - 9:30 pm | Sheila Lukehart (University of Washington, Seattle, WA)
"Antigenic diversity of T. pallidum" |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | GENE EXPRESSION IN DIVERSE ENVIRONMENTS |
| Discussion Leader: Alan Barbour (UC Irvine, Newport Beach CA) |
| 9:00 am - 9:30 am | X. Frank Yang
"Two-component regulatory systems in pathogenic spirochetes" |
| 9:30 am - 10:00 am | Ben Adler (Monash University, Clayton, VIC, Australia)
"The genome of Leptospira: some key features" |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Stephen Barthold (UC Davis, CA)
"Tissue-specific gene expression in infected mouse tissue" |
| 11:00 am - 11:30 am | Jon Skare (Texas A & M, College Station, TX)
"Redox regulation of Borrelia burgdorferi" |
| 11:30 am - 12:00 pm | Ira Schwartz (New York Medical College, Valhalla, NY)
"Whole genome analysis of regulated gene expression" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | PATHOGENESIS |
| Discussion Leader: Richard Ellen (University of Toronto, Canada) |
| 7:30 pm - 8:00 pm | Mario Philipp (Tulane Regional Primate Center, Covington, LA)
"Pathogenesis of neuroborreliosis" |
| 8:00 pm - 8:30 pm | Melissa Caimano (Univ. Connecticut Health Center, Farmington, CT)
"Cellular and molecular components of spirochetal pathogenesis" |
| 8:30 pm - 9:00 pm | Gerald Duhamel (U Nebraska, Lincoln, NE)
"Experimental pathogenesis of Brachyspira pilosicol" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | LIFE AT THE INTERFACE: SPIROCHETE-HOST
ATTACHMENT MOLECULES AND INTERACTIONS |
| Discussion Leader: Barbara Johnson (CDC Fort Collins, CO) |
| 9:00 am - 9:30 am | Albert Ko (Weill Medical College of Cornell University, Salvado, Bahia Brazil)
"Surface-associated Ig-Like Proteins in Pathogenic Leptospira" |
| 9:30 am - 10:00 am | Sven Bergstrom (University of UMEA, Sweden)
"Proteolytic processing of infection-associated proteins in Borrelia" |
| 10:00 am - 10:30 am | Coffee Break |
| 10:30 am - 11:00 am | Chris Fenno (University of Michigan, Ann Arbor, MI)
"T. denticola surface complexes" |
| 11:00 am - 11:30 am | Caroline Cameron (University of Washington, Seattle, WA)
"ECM Adhesins of Treponema pallidum" |
| 11:30 am - 12:00 pm | John Leong (University of Massachusetts Medical School, Worcester)
"Bacterium-host cell interactions that promote colonization by pathogenic Borreliae" |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session II |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | LATE BREAKING SESSION |
| Discussion Leaders: James Matsunaga (UCLA/VA, Los Angeles, CA) & Felipe Cabello (New York Medical College, Valhalla, NY) |
| Speakers to be selected from poster abstract submissions |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |