Conference Program
 
Lasers In Medicine & Biology
July 2-7, 2006
Holderness School
Holderness, NH
Chairs:
Charles P. Lin & Ralf Brinkmann

Vice Chairs:
Peter T. So & H.J.C.M. Sterenborg

This year the Gordon Conference on Lasers in Medicine and Biology will meet in a new location, at Holderness School in Plymouth, New Hampshire, because our old favorite (Kimball Union Academy) is no longer hosting the GRC. Location aside, we will continue the tradition of presenting cutting-edge research in biomedical optics, in a relaxed, informal setting where there is ample time for discussion and meeting with speakers. There will be nine technical sessions (no parallel sessions) each focusing on a topic of current interest in the field.

In addition, there will be two poster sessions. All participants are encouraged to submit a poster abstract at the time of application. The poster sessions, along with informal discussion during social hours, represent major parts of scientific exchange at the GRC.

Contributors
NIH
AFOSR
Carl Storm Underrepresented Minority Fellowships
Wellman Center for Photomedicine
Beckman Laser Institute
Thorlabs
Johnson & Johnson
Boston Electronics Corporation
SUNDAY
2:00 pm - 11:00 pmArrival and Check-in
6:00 pmDinner
Welcome / Introductory Comments
7:30 pm - 9:30 pmCellular/Subcellular Imaging and Manipulation
Discussion Leader: Peter So (MIT)
7:30 pm - 8:00 pm Jason Shear (University of Texas at Austin)
"Interfacing with Dynamic Cellular Systems using Biocompatible Microfabrication"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:40 pm Adela Ben-Yakar (University of Texas at Austin)
"Femtosecond Laser Nanosurgery, Fundamentals and Applications"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:20 pm Eric Potma (University of California at Irvine)
"Looking at biology with CARS"
9:20 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
8:45 amGroup Photo
9:00 am - 12:30 pmImaging Brain Function and Disease
Discussion Leader: Elizabeth Hillman (Columbia University)
9:00 am - 9:30 am Brian Bacskai (Massachusetts General Hospital) "In vivo imaging of structure and function in the brains of Alzheimer's mice with multiphoton microscopy"
9:30 am - 9:45 am Discussion
9:45 am - 10:15 am Elizabeth Hillman (Columbia University)
"High resolution functional optical imaging of exposed cortex in-vivo"
10:15 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:30 am Turgut Durduran (University of Pennsylvania)
"Optical Measurement of Cerebral Blood Flow, Oxygenation and Metabolism: From Benchtop to the Clinic"
11:30 am - 11:45 am Discussion
11:45 am - 12:15 pm Jens Steinbrink (Berlin NeuroImaging Center)
"The Blushing and the Glowing Brain: Novel Non-Invasive Optical Methods to Characterize the Function and Pathophysiology of the Central Nerval System"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmRetinal Imaging
Discussion Leader: Christoph Hitzenberger (Medical University Vienna)
7:30 pm - 8:00 pm Dietrich Schweitzer (University Jena, Germany)
"Reflectance and autofluorescence measurements for metabolic studies at the fundus"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:40 pm Johannes deBoer (Harvard Medical School)
"Optical coherence tomography in ophthalmology"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:20 pm Austin Roorda (University of California Berkeley)
"Adaptive Optics Ophthalmoscopy for Clinical and Basic Science"
9:20 pm - 9:30 pm Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNew Technology/Methodology I
Discussion Leader: Vasan Venugopalan (University of California at Irvine)
9:00 am - 9:30 am Joseph P. Culver (Washington University School of Medicine)
"Functional and molecular imaging with diffuse optical tomography: Practical challenges in mouse and man"
9:30 am - 9:45 am Discussion
9:45 am - 10:15 am David Cuccia (University of California, Irvine)
"Modulated Imaging: Quantitative imaging of intrinsic and extrinsic tissue optical properties and chromophores in the spatial frequency domain"
10:15 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:30 am Lihong Wang (University of Washington, St. Louis)
"High-resolution photoacoustic imaging"
11:30 am - 11:45 am Discussion
11:45 am - 12:15 pm Brett Bouma (Harvard Medical School)
"Comprehensive volumetric microscopy with optical frequency-domain imaging"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmCancer Imaging and Therapy
Discussion Leader: Brian Pogue (Dartmouth University)
7:30 pm - 8:00 pm John Frangioni (Harvard Medical School)
"Fluorescence Imaging Systems and Contrast Agents for Real-Time Surgical Guidance"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:40 pm Lothar Lilge (University of Toronto)
"Optical Transillumination: A physical breast cancer risk indicator?"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:20 pm Brian Wilson (University of Toronto)
"Paradigm Shifts in Photodynamic Therapy"
9:20 pm - 9:30 pm Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNew Technology/Methodology II
Discussion Leader: Irene Georgakoudi (Tufts University)
9:00 am - 9:30 am Changhuei Yang (Caltech)
"Optofluidic Microscope - How to build a fingertip size high resolution microscope?"
9:30 am - 9:45 am Discussion
9:45 am - 10:15 am Emmanuel Beaurepaire (Ecole Polytechnique, INSERM, France)
"Third-harmonic generation (THG) microscopy of cells and tissues: mechanisms of contrast and applications"
10:15 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:30 am Gabriel Popescu (MIT)
"Nanoscale imaging of live cells using optical interferometry"
11:30 am - 11:45 am Discussion
11:45 am - 12:15 pm Yael Roichman (New York University)
"Holographic optical tweezers, reaching into the microscopic world"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmOptical Biosensors
Discussion Leader: Katrin Kneipp (Harvard Medical School)
7:30 pm - 8:00 pm David Walt (Tufts University)
"Optical fiber microarrays"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:40 pm Lisa DeLouise (University of Rochester)
"Exploring the limits of optical detection with porous silicon microcavity sensors"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:20 pm Richard van Dyne (Northwestern University)
"Sensors based on Plasmonics"
9:20 pm - 9:30 pm Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
9:00 am - 12:30 pmNanostructures for Biomedical Applications
Discussion Leader: Gereon Huettmann (Medical Laser Center Luebeck)
9:00 am - 9:30 am Thomas Klar (Ludwig-Maximilians-Universität, München, Germany)
"Bio-Spectroscopy with Gold Nanoparticles"
9:30 am - 9:45 am Discussion
9:45 am - 10:15 am (open)
10:15 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:30 am Christoph Gimmler (University of Hamburg, Germany)
"Nanoparticles for Bio-Labeling"
11:30 am - 11:45 am Discussion
11:45 am - 12:15 pm Elmar Endl (University of Bonn, Germany)
"On the potential use of laser activated nanoparticle mediated cell elimination in biomedical applications"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmNew Era of Molecular Photomedicine
Discussion Leader: Sam Achilefu (University of Washington, St. Louis)
7:30 pm - 8:00 pm Rebecca Drezek (University of Texas at Austin)
"Activatable Nanoparticles for Molecular Imaging and Targeted Therapy of Cancer"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:40 pm Gang Zheng (University of Pennsylvania)
"Molecular beacons as integrated optical imaging and photodynamic therapy agents"
8:40 pm - 8:50 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart