Gordon Research Conferences
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Conference Program
 
Metals in Biology
January 29 - February 3, 2006
Four Points Sheraton / Holiday Inn Express
Ventura, CA
Chair:
David M. Dooley

Vice Chair:
Robert A. Scott

Related Meeting Information
The Metals in Biology Gordon Research Conference was held in conjunction with the Bioinorganic Chemistry Gordon-Kenan Research Seminar. Please refer to the Bioinorganic Chemistry GKRS web page for more information.

SUNDAY
4:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 9:00 pmOpening Session
7:30 pm - 7:45 pmDavid M. Dooley (Montana State University)
"Welcome & Introduction"
Chair: Julie A. Kovacs (University of Washington)
7:45 pm - 8:45 pmEdward I. Stiefel (Princeton University)
"Microbes as Inorganic Chemists: Harnessing Iron While Avoiding its Dangers"
8:45 pm - 9:00 pmDiscussion
9:00 pm Chairs Reception / Poster Session
MONDAY
7:30 am - 8:30 amBreakfast
8:30 amConference Photo
9:00 am - 12:30 pmInorganic Metabolism
Chair: Svetlana Lutsenko (Oregon Health Sciences University)
9:00 am - 9:30 amPeter M. Kroneck (Universität Konstanz)
"Nitrous Oxide (N2O) Respiration: CuA, CuZ, and More"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 am Christopher Rensing (University of Arizona)
"Arsenite(III)methyltransferase from Rhodopseudomonas palustris: Characterization of a Novel Arsenite Resistance Mechanism"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 am Caroline Kisker (SUNY Stony Brook)
"Structural Insights into Sulfite Oxidase Deficiency"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmDavid C. Richardson (University of East Anglia)
"Multi-heme Cytochromes: Evolutionary Links between the Nitrogen and Iron Cycles"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 6:00 pmFree Time
6:00 pmDinner
7:30 pm - 9:30 pmInorganic Sensing and Signaling
Chair: Ann English (Concordia University)
7:30 pm - 7:55 pmChuan He (University of Chicago)
"Study of the MerR Proteins: Selective Metal Ion Sensing and Constructing Metal Ion Biosensors"
7:55 pm - 8:10 pmDiscussion
8:10 pm - 8:35 pmJudith N. Burstyn (University of Wisconsin)
"Allostery in the CO Sensing Heme Protein, CooA"
8:35 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pmDavid Benson (Wayne State University)
"Electron Transfer Facilitates Small Molecule Biosensing with Semiconducting Nanoparticles"
9:15 pm - 9:30 pmDiscussion
9:30 pm Poster Session
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMechanistic Bioinorganic Chemistry
Chair: Charles Riordan (University of Delaware)
9:00 am - 9:30 amRichard G. Finke (Colorado State University)
"A Coenzyme B12 Test of the Enzyme-Enhanced H-Tunneling Hypothesis"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 am William Tolman (University of Minnesota)
"Using Synthetic Models to Understand Reactive Intermediates and Unusual Structures in Copper Proteins"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:20 am Aimin Liu (University of Mississippi Medical Center)
"Metallocofactor in alpha-Amino-beta-Carboxymuconic-epsilon-Semialdehyde Decarboxylase (ACMSD): Structure, Function, Mechanism"
11:20 am - 11:30 amDiscussion
11:30 am - 12:00 pm Justine Roth (Johns Hopkins University)
"Characterizing Activated Oxygen Intermediates in Metalloenzymes"
12:00 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 6:00 pmFree Time
6:00 pmDinner
7:30 pm - 9:30 pmMetals in Medical Imaging, Therapeutics
Chair: Thomas J. Meade (Northwestern University)
7:30 pm - 7:55 pmJonathan L. Sessler (University of Texas)
"Expanded Porphyrins. A New Approach to Drug Development"
7:55 pm - 8:10 pmDiscussion
8:10 pm - 8:35 pmRalph Weissleder (Harvard University)
"Metal based nanoparticles for imaging"
8:35 pm - 8:50 pmDiscussion
8:50 pm - 9:15 pm William Bornmann (UT M.D. Anderson Cancer Center)
9:15 pm - 9:30 pmDiscussion
9:30 pm Poster Session
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmApplications of Theory/Computation
Chair: Abhik Ghosh (Tromsø University)
9:00 am - 9:30 amThomas C. Brunold (University of Wisconsin)
"Spectroscopic/Computational Studies of Coenzyme B12 Structure and Function"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 amEric Oldfield (University of Illinois, Urbana-Champaign)
"Theoretical Approaches to Metalloprotein Structure, Function, and Inhibition"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amSharon Hammes-Schiffer (Pennsylvania State University)
"Proton-Coupled Electron Transfer Reactions in Solution and Proteins"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmUlf Ryde (Lund University)
"Combining Quantum Chemical Calculations with EXAFS, Crystallography, and NMR for Accurate Metalloprotein Structures"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 6:00 pmFree Time
5:00 pm - 6:00 pmChairs' Business Meeting (by invitation)
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair Elect; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair Elect)
7:30 pm - 9:30 pmMetalloproteomics/Metallogenomics: Developing Technologies
7:30 pm - 7:45 pmChair: Robert A. Scott (University of Georgia)
"Introduction"
7:45 pm - 8:10 pmMichael W. Crowder (Miami University)
"Probing the Zn(II)-responsive Proteins in E. coli with Proteomic and Genomic Approaches"
8:10 pm - 8:25 pmDiscussion
8:25 pm - 8:50 pmPatrick G. Grant (LLNL)
"Quantitative Metalloproteomics in Human Erythrocytes"
8:50 pm - 9:05 pmDiscussion
9:05 pm - 9:20 pm Deborah Zamble (University of Toronto)
"New Methods for Finding Metalloproteins"
9:20 pm - 9:30 pmDiscussion
9:30 pm Poster Session
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMolybdenum in Biology
Chair: John Enemark (University of Arizona)
9:00 am - 9:30 amMartin L. Kirk (University of New Mexico)
"New Insights into the Mechanism of Pyranopterin Molybdenum Enzymes: Electronic Structure Contributions to Catalysis"
9:30 am - 9:45 amDiscussion
9:45 am - 10:15 am Ralf Mendel (Ruhr Universität Bochum)
"Biogenesis of the molybdenum cofactor in plants and humans"
10:15 am - 10:30 amDiscussion
10:30 am - 11:00 amCoffee Break
11:00 am - 11:30 amMarkus W. Ribbe (University of California, Irvine)
"Nitrogenase: A Paradigm for Metallocluster Assembly"
11:30 am - 11:45 amDiscussion
11:45 am - 12:15 pmC. Russ Hille (Ohio State University)
"Structure and Function of Xanthine Oxidoreductase"
12:15 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmJoint Poster Session (presented by Gordon Research Seminar)
6:00 pmDinner
7:30 pm - 8:45 pmJoint Session with Gordon Research Seminar
Chair: David M. Dooley (Montana State University)
7:30 pm - 8:30 pmAmy Rosenzweig (Northwestern University)
"The Quest for the Particulate Methane Monooxygenase Active Site"
8:30 pm - 8:45 pmDiscussion
8:45 pm Joint Poster Session (presented by Gordon Research Seminar)
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

 
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