| SUNDAY |
| 2:00 pm - 11:00 pm | Arrival and Check-in |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Organometallics in Synthesis 1 |
| Discussion Leader: Peter Wipf (University of Pittsburgh) |
| 7:30 pm - 7:50 pm | Hannah Yu (Lilly)
"Stereoselective Synthesis of Dibenzoxapine Containing Nuclear Hormone Receptor Modulators Using Palladium-catalyzed Cascade Reaction" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Martin Hiersemann (Dortmund)
"Development and Application of the Catalytic Asymmetric Claisen Rearrangement (CAC)" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | John Hartwig (University of Illinois)
"Discovery and Understanding of New Transition Metal-Catalyzed Reactions" |
| 9:20 pm - 9:30 pm | Discussion |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 8:30 am | Group Photo |
| 9:00 am - 10:30 am | Asymmetric Synthesis |
| Discussion Leader: Tarek Sammakia (University of Colorado) |
| 9:00 am - 9:20 am | Debra Wallace (Merck)
"Catalytic Asymmetric Reactions in the Synthesis of Complex Drug Targets" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Paul Carlier (Virginia Tech)
"Transiently Non-racemic Enolates: Synthesis of Enantiopure 'Quaternary' Benzodiazepines" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Guigen Li (Texas Tech)
"Asymmetric Halo Aldol Reaction for Tandem X-C/C-C Bond Formations" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 12:30 pm | Synthetic Methodology and Process Research 1 |
| Discussion Leader: Angelika Fretzen (Microbia) |
| 10:45 am - 11:10 am | Arun Ghosh (Pfizer)
"Process Research and Scale-up of a Pyrazolotriazine Drug Candidate" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | Babak Borhan (Michigan State)
"Use of Ylides in Preparation of 5-Member Ring Heterocycles via One Carbon Homologative Relay Ring Expansion of Epoxy Alcohols and Aziridinols" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | John Porco (Boston University)
"Organic Reactions and Processes Inspired by Complex Natural Products" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #1 |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Organometallics in Synthesis 2 |
| Discussion Leader: Lisa McElwee-White (University of Florida) |
| 7:30 pm - 7:50 pm | Rai-Shung Liu (National Tsing-Hua University)
"Metal-catalyzed Cycloisomerization of Acyclic Alkynes of Mechanistic and Synthetic Interest" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | David Vicic (University of Arkansas)
"Organometallic Aspects of Alkyl-Alkyl Cross-Coupling Reactions" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Hélène Lebel (University of Montreal)
"Catalytic Activation of Nitrogen Derivatives with Transition Metal Complexes" |
| 9:20 pm - 9:30 pm | Discussion |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:30 am | Synthetic Methodology and Process Research 2 |
| Discussion Leader: Cecile Savarin (Merck) |
| 9:00 am - 9:20 am | John Carey (GlaxoSmithKline)
"Analysis of the Reactions used for the Preparation of Drug Candidate Molecules" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | David Hill (Abbott)
"Scale-up Synthesis of BCL-2 Inhibitor ABT-737" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Allison Frontier (Rochester)
"The Nazarov Cyclization: New Twists" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 12:30 pm | Organometallics in Synthesis 3 |
| Discussion Leader: Rick Bunt (Middlebury) |
| 10:45 am - 11:10 am | Christina White (University of Illinois)
"Hydrocarbon Oxidation Methods for Synthesis" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | Daesung Lee (Wisconsin)
"Ene-Yne Coupling Reactions for Synthesis" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Janis Louie (University of Utah)
"Recent Progress in Nickel Catalyzed Cycloaddition Chemistry" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time / ORP Gold Classic |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Natural Products Total Synthesis |
| Discussion Leader: Frank McDonald (Emory) |
| 7:30 pm - 7:50 pm | Armen Zakarian (Florida State University)
"Progress toward the Total Synthesis of Pinnatoxin A" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20pm | Lawrence Williams (Rutgers University)
"Progress towards the Total Synthesis of Psymberin" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Daniel Romo (Texas A&M University)
"Asymmetric Synthesis of Bicyclic Beta-Lactones Inspired by Omuralide and Related Natural Products" |
| 9:20 pm - 9:30 pm | Discussion |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:30 am | Organocatalysis |
| Discussion Leader: Rick Danheiser (MIT) |
| 9:00 am - 9:20 am | Karl Scheidt (Northwestern)
"Recent Developments in Carbene Catalysis" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Ohyun Kwon (UCLA)
"Phosphine Catalysis of Allenes" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Jeffrey Bode (UC Santa Barbara)
"Highly Enantioselective, NHC-Catalyzed Annulation Reactions" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 12:30 pm | Synthetic Methodology and Process Research 3 |
| Discussion Leader: Jean Suffert (CNRS) |
| 10:45 am - 11:10 am | Mike Harmata (University of Missouri -Columbia)
"Benzothiazines in Organic Synthesis" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | Rod Parsons (BMS)
"Discovery and Development of an Efficient Process for Synthesis of the Tetrazole Core of BMS-317180" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Peter Somfai (Royal Institute of Technology)
"Allylsilanes beyond Sakurai-allylations: Synthetic Approaches towards (+)-Alexine Utilizing a Novel [3+2]-Annulation Reaction" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session #2 |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | Synthetic Methodology and Process Research 4 |
| Discussion Leader: Mukund Sibi (North Dakota State University) |
| 7:30 pm - 7:50 pm | Thomas Storz (Amgen)
"Biologic or Small Molecule?? -Multiple Challenges in the Synthesis & Scale-Up of a 20K-PEG-conjugated, Selective Bradykinin B-1 Antagonist" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Greg Dudley (Florida State University)
"Simplifying the Art of Organic Synthesis" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 9:20 pm | Steven Weinreb (Penn State)
"Methodology for Synthesis of Alkaloids" |
| 9:20 pm - 9:30 pm | Discussion |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 10:30 am | Synthetic Methodology and Process Research 5 |
| Discussion Leader: Art Harms (Bausch & Lomb) |
| 9:00 am - 9:20 am | Bob Grossman (University of Kentucky)
"Catalytic Classical Resolution" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Nathan Yee (Boehringer-Ingelheim)
"Development of a Scalable Synthesis of BILN 2061, a Novel HCV Protease Inhibitor" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Paolo Crotti (University of Pisa)
"Regio- and Stereoselectivity of the Addition Reactions of Nucleophiles to the Diastereoisomeric D-Allal- and D-Galactal-Derived Allyl Epoxides and Aziridines" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 10:45 am - 12:30 pm | Organometallics in Synthesis 4 |
| Discussion Leader: Jackie Milne (Amgen) |
| 10:45 am - 11:10 am | Sherry Chemler (SUNY Buffalo)
"Copper(II) Carboxylate Promoted Oxidative Cyclizations: Intramolecular Carboamination and Diamination of Unactivated Olefins" |
| 11:10 am - 11:20 am | Discussion |
| 11:20 am - 11:45 am | Laurel Schafer (University of British Columbia)
"A New Class of Enantioselective Olefin Hydroamination Catalysts: Chiral Amidates as Modular Ligands for Early Transition Metals" |
| 11:45 am - 11:55 am | Discussion |
| 11:55 am - 12:20 pm | Jean-Luc Montchamp (Texas Christian)
"Advances in Phosphorus-Carbon Bond-Forming Reactions" |
| 12:20 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Chair's Reception |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Poster Presentations and Featured Speaker |
| Discussion Leader: Scott Sieburth (Temple) |
| 7:30 pm - 7:50 pm | TBA |
| 7:50 pm - 8:10 pm | TBA |
| 8:10 pm - 8:30 pm | TBA |
| 8:30 pm - 9:20 pm | Richard Palmer (University of Alberta)
"Asymmetric Synthesis at the Whole-Organism Level: Development and Evolution of Biological Asymmetries" |
| 9:20 pm - 9:30 pm | Discussion |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Depart |