Gordon Research Conferences
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Conference Program
 
Oxygen Radicals
February 5-10, 2006
Ventura Beach Marriott
Ventura, CA

SUNDAY
4:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 9:00 pmCHEMISTRY OF REDOX SIGNALING
Chair: Garry Buettner (University of Iowa)
7:30 pm - 8:05 pmJon Fukuto (UCLA)
Reactive nitrogen species in signal transduction
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:50 pm Aron B. Fisher (University of Pennsylvania)
Peroxiredoxin VI,a dual function enzyme with glutathione peroxidase and phospholipase A2 activities
9:50 pm - 9:00 pmDiscussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIRON HOMEOSTASIS AND NITRIC OXIDE METABOLISM & EMERGING TECHNOLOGIES AND BIOMARKERS IN FREE RADICAL BIOLOGY
Chair: Balaraman Kalyanaraman (Medical College of Wisconsin)
9:00 am - 9:05 am Announcements and Chair's Introductory Remarks
9:05 am - 9:35 amJean Claude Drapier (Centre National de la Recherche Scientifique, Gif-sur-Yvette, France)
Nitric oxide and peroxynitrite in the modulation of iron regulatory proteins
9:35 am - 9:45 amDiscussion
9:45 am - 10:00 amDavid M. Krzywanski (University of Alabama at Birmingham)
Nitrogen dioxide induced protein nitration does not correlate with acute cell injury
10:00 am - 10:10 amDiscussion
10:10 am - 10:30 amCoffee Break
10:30 am - 11:05 amRonald Mason (National Institutes of Health, USA)
Capturing Protein and DNA radicals in Time and Space by Immuno-spin trapping
11:05 am - 11:15 amDiscussion
11:15 amGroup Photo
11:30 am - 12:00 pmOhara Augusto (Instituto de Química-Universidade de São Paulo, Brazil)
Carbonate radical: detection, biomarkers and bioactivities
12:00 pm - 12:10 pmDiscussion
12:10 pm - 12:25 pmSilvina Bartesaghi (Universidad de la República, Montevideo, Uruguay)
Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe N-t-BOC L-tyrosine tert butyl ester (BTBE)
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:00 pmNADPH OXIDASES IN SIGNALING
Chair: John Eaton (University of Louisville)
7:30 pm - 8:05 pm David Lambeth (Emory University)
The NOX family of proteins
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:50 pmTom Leto (National Institutes of Health, USA)
Regulation and composition of non-phagocyte oxidases
8:50 pm - 9:00 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmOXIDANTS-ANTIOXIDANTS IN INFECTION AND INFLAMMATION
Chair: Etsuo Niki (Human Stress Signal Research Center, Midorigaoka, Ikeda, Japan)
9:00 am - 9:05 amAnnouncements and Chair's Introductory Remarks
9:04 am - 9:40 am Madia Trujillo (Universidad de la República, Montevideo, Uruguay)
Trypanothione and peroxiredoxins during mammalian cell infection by trypanosomatids
9:40 am - 9:50 amDiscussion
9:50 am - 10:10 amHoracio Botti (Universidad de la República, Montevideo, Uruguay)
Studies on the Formation of Redox Variants of Human Serum Albumin: Focusing on Sulfur Oxidation and Sulfinate Formation at C34 by Electrophiles and Free Radicals
10:10 am - 10:15 amDiscussion
10:15 am - 10:35 amCoffee Break
10:35 am - 11:10 amMary Sorci Thomas (Wake Forrest)
Role of HDL ApoA-I in inflammation and cholesterol homeostasis
11:10 am - 11:20 amDiscussion
11:20 am - 11:55 amStefan Ryter (University of Pittsburgh)
Carbon monoxide suppresses inflammation
11:55 am - 12:05 pmDiscussion
12:05 pm - 12:25 pmAlireza Mani (University College London)
The metabolism of chlorotyrosine, and identification
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:00 pmLIPID DERIVED RADICALS AND NITRIC OXIDE
Chair: Bruce Freeman (University of Pittsburgh)
7:30 pm - 8:05 pm Homero Rubbo (Universidad de la República, Montevideo, Uruguay)
Biological activity of nitrolipids and nitric oxide derivatives of vitamin E
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:50 pm Paul Baker (UAB)
Mass spectrometric detection and characterization of nitrolipids
8:50 pm - 9:00 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTHIOL OXIDATION IN SIGNALING
Chair: Robert Floyd (Oklahoma Medical Research Foundation)
9:00 am - 9:05 amAnnouncements and Chair's Introductory Remarks
9:05 am - 9:40 amMatilde Maiorino (University of Padova, Italy)
Non-antioxidant functions of glutathione peroxidases
9:40 am - 9:50 amDiscussion
9:50 am - 10:10 amAlessandra Rinna (University of California, Merced)
Stimulation of the alveolar macrophage respiratory burst by ADP causes selective glutathionylation of protein tyrosine phosphatase 1B
10:10 am - 10:15 amDiscussion
10:15 am - 10:35 amCoffee Break
10:35 am - 11:10 amTak Yee Aw (Louisiana State University)
The redox state regulates signaling
11:10 am - 11:20 amDiscussion
11:20 am - 11:55 amP. Boon Chock (National Institutes of Health, USA)
The physiological function of glutathionylated actin
11:55 am - 12:05 pmDiscussion
12:05 pm - 12:25 pmFernando Antunes (Instituto de Investigação Científica Bento da Rocha Cabral, Lisboa, Portugal)
Regulation of plasma membrane permeability to H2O2 during adaptation to H2O2
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:00 pmSOURCES OF REACTIVE SPECIES
Chair: Kelvin Davies (University of Southern California)
7:30 pm - 8:05 pmEdgar Pick (Sackler School of Medicine, Tel Aviv University, Israel)
Regulation of the phagocyte NADPH oxidase by cytosolic components - From membrane recruitment to "meeting Mr. Right"
8:05 pm - 8:15 pmDiscussion
8:15 pm - 8:50 pmPaul Brookes (University of Rochester)
Mitochondria, S-nitrosothiols and cardiac ischemia
8:50 pm - 9:00 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:40 amREDOX AND ELECTROPHILIC SIGNALING
Chair: Lester Packer (University of Southern California)
9:00 am - 9:05 amAnnouncements and Chair's Introductory Remarks
9:05 am - 9:40 amAkira Kobayashi (University of Tsukuba, Japan)
Nrf2-Keap pathways
9:40 am - 9:50 amDiscussion
9:50 am - 10:05 amDouglas Thomas (National Institutes of Health, USA)
Superoxide fluxes control NO-induced post-translational regulation of sGC, p53, and HIF-1a
10:05 am - 10:15 amDiscussion
10:15 am - 10:35 amCoffee Break
10:35 am - 11:10 amMichel Toledano (Service de Biologie Moléculaire Systémique, Gif-sur-Yvette, France)
Signaling for regulation of transcription factors
11:10 am - 11:20 amDiscussion
11:20 am - 11:50 amAimee Landar (UAB)
The electrophile responsive proteome: characterization and functional significance
11:50 am - 12:00 pmDiscussion
12:00 pm - 12:30 pmPanel Discussion
What Have We Learned In Twenty Five Years Of Oxygen Radical Gordon Conferences And What Do We Still Need To Learn?
Discussion Leader: Henry Jay Forman
Panel Members: Kelvin Davies, Bruce Freeman, Balaraman Kalyanaraman, John Eaton, Etsuo Niki, Robert Floyd, Garry Buettner, Norman Krinsky, Lester Packer
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmConference Banquet
8:00 pm - 9:00 pmCONFERENCE KEYNOTE LECTURE
Chair: Norman Krinsky
8:00 pm - 8:50 pm Christine Winterbourn (New Zealand)
Understanding oxidative stress: From the chemistry of superoxide to the lungs of babies
8:50 pm - 9:00 pmDiscussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

 
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