Gordon Research Conferences
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Conference Program
 
Aging, Biology of
September 23-28, 2007
Les Diablerets Conference Center
Les Diablerets, Switzerland

Contributors

SUNDAY
4:00 pm - 9:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:10 pmKEYNOTE LECTURE
7:40 pm - 7:50 pmDiscussion Leader: Andrzej Bartke (Southern Illinois University, Springfield, IL, USA)
7:50 pm - 8:40 pmSteve Helfand (Brown University, Providence, RI, USA)
"Calorie reduction and life span extension: a genetic pathway in the fly"
8:40 pm - 9:10 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:10 pmIMPACT OF DNA DAMAGE AND REPAIR FUNCTIONS ON AGING
9:00 am - 9:05 amDiscussion Leader: Jan Vijg (Buck Institute for Age Research, Novato CA, USA)
9:05 am - 9:25 am Dan Gottschling (Fred Hutchinson Cancer Research Center, Seattle WA, USA)
"Yeast Aging and Genomic Instability"
9:25 am - 9:40 am Discussion
9:40 am - 10:00 am Jan Hoeijmakers (Erasmus University, Rotterdam, The Netherlands)
"Accelerated aging in mice lacking DNA repair proteins"
10:00 am - 10:15 am Discussion
10:15 amGroup Photo / Coffee Break
11:00 am - 11:20 am Ignacio Flores (Spanish National Cancer Center, Madrid, Spain)
"Telomeres, DNA repair and aging"
11:20 am - 11:35 am Discussion
11:35 am - 11:55 am Tinna Stevnsner (University of Aarhus, Aarhus, Denmark)
"Mitochondrial DNA repair proteins in aging"
11:55 am - 12:10 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session I
5:30 pm - 7:30 pmACCELERATED AGING
5:30 pm - 5:35 pmDiscussion Leader: Vilhelm Bohr (National Institute of Aging, NIH, Baltimore, MD, USA)
5:35 pm - 5:55 pmMakoto Kuro-o (University of Texas Southwestern Medical Center, Dallas, TX, USA)
"Regulation of aging by klotho"
5:55 pm - 6:05 pm Discussion
6:05 pm - 6:25 pmTom Misteli (National Cancer Institute, NIH, Bethesda, MD, USA)
"The role of nuclear architecture in aging"
6:25 pm - 6:35 pm Discussion
6:35 pm - 6:55 pm Tomas A. Prolla (University of Wisconsin, Madison, WI, USA)
"DNA telomerase gamma mutant mice"
6:55 pm - 7:05 pm Discussion
7:05 pm - 7:25 pm Eline Slagboom (Leiden University Medical Center)
"Maintenance of human familial longevity"
7:25 pm - 7:30 pm Discussion
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmPROTEIN FOLDING/AGGREGATION/DEGRADATION IN AGING
9:00 am - 9:05 amDiscussion Leader: Ana Maria Cuervo (Albert Einstein College of Medicine, Bronx, NY, USA)
9:05 am - 9:25 am Thomas Nyström (Göteborg University, Göteborg, Sweden)
"The role of oxidative carbonylation in protein quality control and senescence"
9:25 am - 9:40 am Discussion
9:40 am - 10:00 am Andrew Dillin (Salk Institute for Biological Studies, La Jolla, CA, USA)
"Age-associated neuroprotection regulated by insulin/IGF-1 signaling: From worm to mouse"
10:00 am - 10:15 am Discussion
10:15 amCoffee Break
10:45 am - 11:05 am Rod Levine (National Heart, Lung and Blood Institute, Bethesda, MD, USA)
"Methionine in Proteins: Macromolecular Bodyguards?"
11:05 am - 11:20 am Discussion
11:20 am - 11:40 am Bertrand Friguet (University of Paris 7/Denis Diderot, Paris, France)
"Proteasome function in aging"
11:40 am - 11:55 am Discussion
11:55 am - 12:15 pm Deborah Ferrington (University of Minnesota, Minneapolis, MN, USA)
"Novel roles for immunoproteasome in aging, stress, and disease"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session II
5:30 pm - 7:25 pmIMMUNOSENESCENCE / LIPID SIGNALING AND AGING
5:30 pm - 5:40 pmDiscussion Leader: Rita Effros (UCLA, Los Angeles, CA, USA)
5:40 pm - 6:00 pm Graham Pawelec (University of Tübingen, Tübingen, Germany)
"Acceleration of human immunosenescence by cytomegalovirus"
6:00 pm - 6:15 pm Discussion
6:15 pm - 6:35 pm Beatrix Grubeck-Loebenstein (Austrian Academy of Science, Innsbruck, Austria)
"Memory T-cells in aging"
6:35 pm - 6:50 pm Discussion
6:50 pm - 7:10 pm Patrick Schrauwen (Maastricht University, Maastricht, The Netherlands)
"Involvement of UCP3 in mild uncoupling and lipotoxicity"
7:10 pm - 7:25 pm Discussion
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSTEM CELLS & AGING
9:00 am - 9:10 amDiscussion Leader: George Martin (University of Washington, Seattle WA, USA)
9:10 am - 9:30 am Nadia Rosenthal (EMBL Mouse Biology Unit, Monterotondo-Scalo, Italy)
"Aging and stem cells"
9:30 am - 9:45 am Discussion
9:45 am - 10:05 am Charlotte Peterson (University of Arkansas for Medical Sciences, Little Rock, AR, USA)
"Age-associated changes in muscle stem cells"
10:05 am - 10:20 am Discussion
10:20 amCoffee Break
10:50 am - 11:10 am Jonathan Tilly (Harvard Medical School, Boston, MA, USA)
"Stem cells and ovarian aging"
11:10 am - 11:25 am Discussion
11:25 am - 11:45 am K. Lenhard Rudoph (Medical School Hannover, Germany)
"Exo1 deletion prevents DNA damage signal induction and prolongs lifespan of telomere dysfunctional mice"
11:45 am - 12:00 pm Discussion
12:00 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session III
5:30 pm - 7:25 pmTHE ROLE OF NUCLEAR RECEPTORS IN AGING
5:30 pm - 5:40 pmDiscussion Leader: Gordon Lithgow (Buck Institute for Age Research, Novato CA, USA)
5:40 pm - 6:00 pm Adam Antebi (Baylor College of Medicine, Houston, TX, USA)
"Nuclear receptor control of C. elegans development and aging"
6:00 pm - 6:15 pm Discussion
6:15 pm - 6:35 pm Gretchen Darlington (Baylor College of Medicine, Houston, TX, USA)
"The role of detoxification pathways in longevity"
6:35 pm - 6:50 pm Discussion
6:50 pm - 7:10 pm Chris Corton (US Environmental Protection Agency, Research Triangle Park, NC, USA)
"Alterations in the expression of xenobiotic metabolism genes in mammals by aging and environmental factors"
7:10 pm - 7:25 pm Discussion
7:25 pm - 8:00 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSTRESS RESISTANCE AND HEALTH SPAN
9:00 am - 9:05 amDiscussion Leader: Cynthia Kenyon (University of California, San Francisco, CA, USA)
9:05 am - 9:25 am Monica Driscoll (Rutgers, Piscataway NJ, USA)
"Defining how to age well: Outlining molecular strategies to extend health span"
9:25 am - 9:40 am Discussion
9:40 am - 10:00 am Tom Johnson (University of Colorado at Boulder, Boulder CO, USA)
"Worm regulation of stress resistance"
10:00 am - 10:15 am Discussion
10:15 amCoffee Break
10:45 am - 11:05 am Arlan Richardson (South Texas Veteran’s Health Care System-Audie Murphy Division and The University of Texas Health Science Center, San Antonio TX, USA)
"Novel proteomic methods to study the effect of age on protein oxidation and conformation"
11:05 am - 11:20 am Discussion
11:20 am - 11:40 am Heinz Osiewacz (Johann Wolfgang Goethe University, Frankfurt am Main, Germany)
"Identification and manipulation of molecular pathways controlling the health span of the fungal ageing model Podospora anserina"
11:40 am - 11:55 am Discussion
11:55 am - 12:25 pm 3 Hot Poster Talks (6 min + 4 min discussion each)
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session IV
5:30 pm - 7:30 pmINTERVENTIONS & HEALTHY AGING
5:30 pm - 5:35 pmDiscussion Leaders: Pamela Larsen (University of Texas Health Science Center, San Antonio, TX, USA), Janet Lord (Birmingham University Medical School, Birmingham, UK), David Sinclair (Harvard Medical School, Boston, MA, USA)
5:35 pm - 5:55 pm Rafael de Cabo (National Institute of Aging, NIH, Baltimore MD, USA)
"In vitro and in vivo analysis of caloric restriction mimetics"
5:55 pm - 6:05 pm Discussion
6:05 pm - 6:25 pm Cathy Wolkow (NIA/IRP, Baltimore MD, USA)
"Pharmacologic and genetic approaches to ensure healthy aging in the nematode, C. elegans"
6:25 pm - 6:35 pm Discussion
6:35 pm - 6:55 pm Etienne Baulieu (INSERM Unit 788, Paris, France)
"Steroids and healthy aging: From human beings to C. elegans"
6:55 pm - 7:05 pm Discussion
7:05 pm - 7:25 pm Charles Brenner (Dartmouth Medical School, Lebanon NH, USA)
"Regulation of NAD+ Biosynthesis in Yeast Replicative Lifespan: Don't Hold the Calories"
7:25 pm - 7:30 pm Discussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

 
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