Gordon Research Conferences
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Conference Program
 
Amygdala in Health & Disease
Contributions to Emotional Memories
July 29 - August 3, 2007
Bates College
Lewiston, ME
Chairs:
Pankaj Sah & Andreas Luthi

Vice Chairs:
Denis Pare & Joe Ledoux

The amygdala is a cerebral structure of the temporal lobe that plays a critical role in the expression of emotions and the learning of new emotional responses. Much evidence suggests that human anxiety disorders result from anomalies in amygdala function. During the conference, internationally renowned basic and clinical researchers will present their latest findings on the amygdala. We will focus on research investigating the role of the amygdala in the formation of emotional memories, both normal and pathological. Other aspects of amygdala functions will be considered in subsequent conferences.


Contributors
NATIONAL INSTITUTES OF HEALTH
PFIZER, INC.
NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC.
CELL PRESS
CARL STORM UNDERRPRESENTED MINORITY FELLOWSHIP
CARL ZEISS MICROIMAGING, INC.
THE UNIVERSITY OF QUEENSLAND

SUNDAY
2:00 pm - 11:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pm THE AMYGDALA AND EMOTIONAL MEMORIES
Discussion Leader: Mortimer Mishkin (NIMH)
7:40 pm - 8:25 pmJoseph E LeDoux (NYU)
"Amygdala: From obscure brain region to household word"
8:25 pm - 8:35 pm Discussion
8:35 pm - 9:20 pmRaymond J Dolan (University College, London)
"Insights into the human amygdala from psychology and functional imaging"
9:20 pm - 9:30 pm Discussion
9:30 pm - 11:30 pm Informal Social
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm SYNAPTIC PLASTICITY
Discussion Leader: Patricia Shinnick-Gallagher (UT Galveston)
9:00 am - 9:25 amRoberto Malinow (Cold Spring Harbor)
"Synaptic modifications underlying a form of learning"
9:25 am - 9:35 am Discussion
9:35 am - 10:00 amVadim Y Bolshakov (Harvard)
"Spatiotemporal asymmetry of associative synaptic plasticity in fear conditioning pathways"
10:00 am - 10:10 am Discussion
10:10 am Group Photo / Coffee Break
11:00 am - 11:25 amPo-Wu Gean (National Cheng-Kung University, Taiwan)
"Differential expression of excitatory and inhibitory transmitter receptors in the amygdala after acquisition, extinction and reinstatement of fear memory"
11:25 am - 11:35 am Discussion
11:35 am - 12:00 pmDonald G Rainnie (Emory)
"Modification of spike-timing precision by inhibitory synaptic input and its implications for synaptic plasticity"
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Short Talk: Glen Schafe (Yale)
"Fear memory consolidation: A view from both sides of the thalamo-amygdala synapse"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pm NEUROMODULATION
Discussion Leader: Donald Rainnie (Emory)
7:30 pm - 7:55 pmDenis Paré (Rutgers)
"How does the amygdala facilitate memory formation in emotionally arousing conditions?"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:30 pmAnthony A Grace (University of Pittsburgh)
"Effects of chronic stress on prefrontal cortical-amygdala interactions: A role in the pathophysiology of psychiatric disorders"
8:30 pm - 8:40 pm Discussion
8:40 pm - 8:55 pm Short Talk: Ron Stoop (University of Lausanne)
"Neuropeptidergic modulation in the central amygdala"
8:55 pm - 9:05 pm Discussion
9:05 pm - 9:20 pm Short Talk: James Crane (Queensland Brain Institute, Brisbane)
"Aversive stimuli reset membrane potential oscillation in the amygdala"
9:20 pm - 9:25 pm Discussion
9:30 pm - 11:30 pm Informal Social
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm FEAR CONDITIONING
Discussion Leader: Denis Paré (Rutgers)
9:00 am - 9:25 amStephen Maren (University of Michigan)
"Brain circuits for encoding, retrieving, and inhibiting fear memories"
9:25 am - 9:35 am Discussion
9:35 am - 10:00 amMichael S Fanselow (UCLA)
"What can fear learning without an amygdala tell us about amygdala function?"
10:00 am - 10:10 am Discussion
10:10 am - 10:25 am Short Talk: Sheena Josselyn (University of Toronto)
"Neuronal competition and selection in memory formation"
10:25 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:25 amHans-Christian Pape (University of Münster)
"Signal transduction during fear related memory formation"
11:25 am - 11:35 am Discussion
11:35 am - 12:00 pmJeansok J Kim (Yale)
"Amygdala mediation of stress-induced impairments in hippocampal function"
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Short Talk: Luke R Johnson (NYU)
"Mapping emotional memory within the lateral amygdala"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 6:00 pmFree Time / Optional Excursion
6:00 pmDinner
7:30 pm - 9:30 pm APPETITIVE CONDITIONING/ADDICTION
Discussion Leader: Alex J McDonald (University of South Carolina)
7:30 pm - 7:55 pmMichela Gallagher (Johns Hopkins)
"Amygdala-frontal interactions and reward expectancy"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:30 pmBarry J Everitt (University of Cambridge, UK)
"Neuropsychological mechanisms of appetitive learning: links to drug addiction"
8:30 pm - 8:40 pm Discussion
8:40 pm - 9:05 pmRonald E See (Medical University of South Carolina)
"Drug addiction, relapse, and the amygdala"
9:05 pm - 9:15 pm Discussion
9:15 pm - 9:25 pm Short Talk: Kay Tye (UCSF)
"Rapid changes in the response properties of amygdala neurons occur during reward learning"
9:25 pm - 9:30 pm Discussion
9:30 pm - 11:30 pm Informal Social
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm EXTINCTION
Discussion Leader: Gregory J Quirk (University of San Juan)
9:00 am - 9:25 amGregory J Quirk (University of San Juan)
"Prefrontal-amygdala interactions mediating extinction of conditioned fear"
9:25 am - 9:35 am Discussion
9:35 am - 10:00 amElizabeth A Phelps (NYU)
"Functional imaging studies of fear extinction in humans"
10:00 am - 10:10 am Discussion
10:10 am - 10:25 am Short Talk: Cyril Herry (Friedrich Miescher Institute, Basel)
"Encoding of fear extinction in the basal amygdala"
10:25 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:25 amR. Fredrick Westbrook (University of New South Wales, Australia)
"Role of NMDAR activation in the amygdala on short and long-term extinction of fear reactions"
11:25 am - 11:35 am Discussion
11:35 am - 12:00 pmMichael Davis (Emory)
"Extinction soon after fear conditioning may actually erase fear memories"
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Short Talk: Geoffrey Murphy (University of Michigan, Ann Arbor)
"L-type voltage gated calcium channels mediate consolidation but not extinction of conditioned fear memories in mice"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:30 pm PHYSIOLOGICAL FUNCTION
Discussion Leader: Patrik Vuilleumier (University of Geneva)
7:30 pm - 7:55 pmChristian Büchel (University of Hamburg)
"Response properties of the human amygdala"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:30 pmPaul J Whalen (University of Wisconsin)
"Functional imaging studies of amygdala function"
8:30 pm - 8:40 pm Discussion
8:40 pm - 8:55 pm Short Talk: Tali Sharot (NYU)
"Imaging the future through rose-colored glasses: neural mechanisms of the optimism bias"
8:55 pm - 9:05 pm Discussion
9:05 pm - 9:20 pm Short Talk: Jan Gläscher (Caltech)
"Effects of emotion and working memory load on visual activation in the lateral occipital complex"
9:20 pm - 9:25 pm Discussion
9:30 pm - 11:30 pm Informal Social
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm PSYCHOLOGICAL DISORDERS
Discussion Leader: Ahmad Hariri (University of Pittsburgh)
9:00 am - 9:25 amJoy Hirsch (Columbia)
"Individual differences in anxiety predict amygdala responses to fearful faces"
9:25 am - 9:35 am Discussion
9:35 am - 10:00 amJ Douglas Bremner (Emory)
"Neuroimaging and anxiety disorders"
10:00 am - 10:10 am Discussion
10:10 am - 10:25 am Short Talk: Patrick M Fisher (University of Pittsburgh)
"5-HT regulation of amygdala reactivity via DRN HTR1A and prefrontal HTR2A"
10:25 am - 10:30 am Discussion
10:30 am Coffee Break
11:00 am - 11:25 amRoger K Pitman (Harvard)
"Investigating the pathogenesis of posttraumatic stress disorder with neuroimaging"
11:25 am - 11:35 am Discussion
11:35 am - 12:00 pmWayne C Drevets (NIMH)
"Neuroimaging and neuropathological abnormalities in the amygdala in mood disorders"
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Short Talk: Ruben Alvarez (NIMH)
"Contextual fear conditioning in a virtual environment: Role of the amygdala and hippocampus"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 6:00 pmFree Time / Optional Excursion
6:00 pmDinner
7:30 pm - 9:30 pm TRANSLATIONAL RESEARCH
Discussion Leader: Bruce S McEwen (Rockefeller)
7:30 pm - 7:55 pmSumantra Chattarji (NCBS, Bangalore)
"Good plasticity in a bad neighborhood: implications for stress disorders"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:30 pmChristian Grillon (NIMH)
"Experimental models of fear and anxiety in humans"
8:30 pm - 8:40 pm Discussion
8:40 pm - 8:55 pm Short Talk: Seth Norrholm (Emory)
"Impaired fear inhibition in combat and civilian PTSD patients"
8:55 pm - 9:05 pm Discussion
9:05 pm - 9:20 pm Short Talk: Gal Richter-Levin (University of Haifa)
"Differential modulation of plasticity in hippocampal subregions by the basolateral amygdala"
9:20 pm - 9:25 pm Discussion
9:30 pm - 11:30 pm Informal Social
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture

Funding for this conference was made possible (in part) by R13MM080445-01 from the National Institute of Mental Health and the National Institute on Drug Abuse. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.

 
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