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Bacterial Cell Surfaces
June 22-27, 2008
Colby-Sawyer College
New London, NH
Chairs:
Anne H. Delcour & Jeff Errington

Vice Chairs:
Christine Jacobs-Wagner & Jan P M. Tommassen

The 2008 Gordon Conference on Bacterial Cell Surfaces will present cutting-edge research on the molecular and cellular aspects of the structure and function of bacterial envelopes and surfaces. The Conference will feature a wide range of topics, such as secretion, protein traffic, envelope biogenesis, cell walls, surface polymers, cell envelope stress response, division, transport, and cellular compartmentalization. Invited speakers represent a variety of scientific disciplines, including biochemistry, molecular genetics, structural biology, cell biology and imaging. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.

Contributors
SUNDAY
2:00 pm - 11:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmEnvelope Stress Response
7:40 pm - 7:50 pm Discussion Leader: Tracy Raivio (University of Alberta, Canada)
7:50 pm - 8:15 pm Carol Gross (UCSF)
"Genomic approaches to the bacterial envelope"
8:15 pm - 8:25 pm Discussion
8:25 pm - 8:50 pm Tom Silhavy (Princeton)
"Envelope stress and outer membrane biogenesis"
8:50 pm - 9:00 pm Discussion
9:00 pm - 9:25 pm John Helmann (Cornell)
"A Gram-positive Perspective on Cell Envelope Stress Responses"
9:25 pm - 9:30 pm Discussion
9:30 pm Reception
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSecretion machineries
9:00 am - 9:10 am Discussion Leader: Peter Christie (University of Texas-Houston)
9:10 am - 9:35 am Françoise Jacob-Dubuisson (Institut Pasteur, Lille, France)
"Two-Partner Secretion: the structure of FhaC and beyond"
9:35 am - 9:45 am Discussion
9:45 am - 9:55 am Poster Talk 1: Han Remaut (Birbeck College)
"Fiber Formation Across the Bacterial Outer Membrane by the Chaperone/Usher Pathway"
9:55 am - 10:00 am Discussion
10:00 am Coffee Break / Group Photo
10:30 am - 10:55 am John Mekalanos (Harvard)
"The Needle in the Tail of Type VI Secretion"
10:55 am - 11:05 am Discussion
11:05 am - 11:30 am Alain Filloux (CNRS, Marseille, France)
"The 'P-usher', a novel bacterial transporter involved in fimbrial assembly and TpsA secretion"
11:30 am - 11:40 am Discussion
11:40 am - 12:05 pm Guy Cornelis (Biozentrum, Basel, Switzerland)
"Type III secretion: The Yersinia Ysc injectisome"
12:05 pm - 12:15 pm Discussion
12:15 pm - 12:25 pm Poster Talk 2: Jonathan Dworkin (Columbia University)
"Muropeptides cause bacteria to exit from dormancy via a eukaryotic-like receptor kinase"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmTransport
7:30 pm - 7:40 pm Discussion Leader: Etana Padan (The Hebrew University of Jerusalem)
7:40 pm - 8:05 pm Helen Zgurskaya (University of Oklahoma)
"Function of membrane fusion proteins in transport across two membranes"
8:05 pm - 8:15 pm Discussion
8:15 pm - 8:40 pm Janet Wood (University of Guelph, Canada)
"Osmosensing by ProP and LacY"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:15 pm Jue Chen (Purdue University)
"Crystal structures of the E. coli maltose transporter"
9:15 pm - 9:25 pm Discussion
9:25 pm - 9:30 pm General Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmCell Walls & Cell Shape
9:00 am - 9:10 am Discussion Leader: Kevin Young (University of North Dakota)
9:10 am - 9:35 am Natalie Strynadka (University of British Columbia, Canada)
"Structural, mechanistic and inhibitory analysis of the transglycosylation/transpeptidation steps in peptidoglycan synthesis"
9:35 am - 9:45 am Discussion
9:45 am - 10:00 am Heidi Kaplan (University of Texas - Houston)
"Muropeptide-mediated Signaling During Myxococcus Development"
10:00 am - 10:10 am Discussion
10:10 am Coffee Break
10:40 am - 11:05 am Waldemar Vollmer (University of Newcastle, UK)
"Interactions and activities of PBPs"
11:05 am - 11:15 am Discussion
11:15 am - 11:40 am Andrea Dessen (Institut de Biologie Structurale, Grenoble, France)
"Structural insights into transpeptidation in peptidoglycan synthesis and pilus biogenesis"
11:40 am - 11:50 am Discussion
11:50 am - 12:15 pm Grant Jensen (Caltech)
"New insights into the cytoskeleton, peptidoglycan, and surface appendages from electron cryotomography"
12:15 pm - 12:25 pm Discussion
12:25 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmEnvelope biogenesis
7:30 pm - 7:40 pm Discussion Leader: Chris Raetz (Duke University)
7:40 pm - 8:05 pm Stephen Trent (Medical College of Georgia)
"Outer Surface of Vibrio cholerae: Structural Changes in Lipopolysaccahride"
8:05 pm - 8:15 pm Discussion
8:15 pm - 8:40 pm Martine Bos (University of Utrecht, The Netherlands)
"Outer membrane biogenesis in the non-LPS-dependent gram-negative Neisseria meningitidis"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:15 pm Chris Whitfield (University of Guelph, Canada)
"Coupling polymerization and export of LPS O antigenic polysaccharides by ABC transporters"
9:15 pm - 9:25 pm Discussion
9:25 pm - 9:30 pm General Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmProtein traffic
9:00 am - 9:10 am Discussion Leader: Ross Dalbey (Ohio State University)
9:10 am - 9:35 am Tom Rapoport (Harvard University)
"Mechanisms of protein transport across membranes"
9:35 am - 9:45 am Discussion
9:45 am - 9:55 am Poster Talk 3: Jeffrey Meisner (Emory University)
"Identification of a novel channel that coordinates cell differentiation during endospore formation in Bacillus subtilis"
9:55 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 10:55 am Angelika Grundling (Imperial College London)
“Polyglycerolphosphate LTA synthesis in Staphylococcus aureus: What we know and what we don’t know”
10:55 am - 11:05 am Discussion
11:05 am - 11:30 am Tracy Palmer (University of Dundee, UK)
"The analysis of protein export by the bacterial Tat pathway"
11:30 am - 11:40 am Discussion
11:40 am - 12:05 pm Roland Beckmann (University of Munich, Germany)
"A structural view on co-translational targeting and translocation"
12:05 pm - 12:15 pm Discussion
12:15 pm - 12:25 pm Poster Talk 4: Alessandro Senes (University of Pennsylvania)
"Computational de-novo design and experimental characterization of an electron transfer membrane protein"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:30 pmCell Division
7:30 pm - 7:40 pm Discussion Leader: Bill Margolin (University of Texas - Houston)
7:40 pm - 8:05 pm Piet de Boer (Case Western University)
"The cell constriction apparatus in E.coli"
8:05 pm - 8:15 pm Discussion
8:15 pm - 8:40 pm Kenn Gerdes (University of Newcastle, UK)
"Novel coiled-coil cell division factor ZapB in Escherichia coli"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:15 pm Fusinita van den Ent (MRC, Cambridge, UK)
"The crystal structure of FtsQ"
9:15 pm - 9:25 pm Discussion
9:25 pm - 9:30 pm General Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmSurface polymers and cell contact
9:00 am - 9:10 am Discussion Leader: David Thanassi (Stony Brook University)
9:10 am - 9:35 am David Zusman (Berkeley)
"Localization of FrzCD, a cytoplasmic chemoreceptor from Myxococcus xanthus, is dynamic and changes with cell-cell contact"
9:35 am - 9:45 am Discussion
9:45 am - 10:00 am Susan Buchanan (NIH)
"Secretion and adhesion by Gram-negative pathogens"
10:00 am - 10:10 am Discussion
10:10 am Coffee Break
10:40 am - 11:05 am Paul Messner (Universität für Bodenkultur, Vienna, Austria)
"Bacterial surface layer protein glycosylation"
11:05 am - 11:15 am Discussion
11:15 am - 11:40 am Matthew Chapman (University of Michigan)
"Polymerizing the fiber between bacteria and host cells: Functional amyloid biogenesis"
11:40 am - 11:50 am Discussion
11:50 am - 12:15 pm Scott Hultgren (Washington University)
"Chaperone/Usher Pili: Structural and Functional Snapshots in Uropathogenic E. coli"
12:15 pm - 12:25 pm Discussion
12:25 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmCellular compartmentalization
7:30 pm - 7:40 pm Discussion Leader: Janine Maddock (University of Michigan)
7:40 pm - 8:05 pm Klas Flärdh (University of Lund, Sweden)
"Control of apical growth in Streptomyces"
8:05 pm - 8:15 pm Discussion
8:15 pm - 8:40 pm Lotte Sogaard-Andersen (Max Planck Institute-Marburg, Germany)
"Regulation by protein compartmentalization within and between cellular compartments"
8:40 pm - 8:50 pm Discussion
8:50 pm - 9:15 pm Yves Brun (Indiana University)
"Using cell shape to improve nutrient uptake: function and compartmentalization of the Caulobacter stalk"
9:15 pm - 9:25 pm Discussion
9:25 pm - 9:30 pm General Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart
 
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