Gordon Research Conferences
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Conference Program
 
Biomineralization
August 10-15, 2008
Colby-Sawyer College
New London, NH
Chair:
James J. De Yoreo

Vice Chair:
Lia Addadi

The objective of the Gordon Research Conference on Biomineralization is to explore the biological, chemical and physical controls on biomineralization in vertebrate, invertebrate, plant and biomimetic systems. Particular attention is paid to the consequences of interactions at the organic-inorganic interface. The interest in this topic stems from the important role that biomineralization processes play in biology, biotechnology, medicine, chemistry, interfacial science, materials science, and nanotechnology. Over the years attendees of this conference have witnessed the spectacular advances made in the field of biomineralization, which have been, in part, due to the interactions and collaborations stimulated by this GRC. The goal of this year's GRC is to bring together chemists, physicists, biologists, physicians and engineers, who would otherwise not overlap on the conference circuit, in a setting that promotes cross-disciplinary fertilization of new ideas. In doing so, our intent is to create the premier venue to discuss fundamental and applied aspects of biomineralization that intersect biology, chemistry and materials science.

We anticipate an exciting meeting with invited oral sessions that will cover cellular and genetic controls on mineral formation, in vitro models of mineralization, interactions and molecular contacts between macromolecular and mineral components, pathological mineralization, macromolecular scaffolds for materials synthesis and organization, new directions in tissue engineering, biomineral architecture in marine systems, the link between architecture and function, and biomineralization through time. Special emphasis will be placed on novel unpublished results, new experimental techniques, and the role of simulation and modeling.

The oral sessions will be followed by the highly successful afternoon poster sessions. The poster sessions provide all conferees with the opportunity to present their latest research and to exchange ideas in a more informal setting. As in the past, this opportunity will continue during the nightly social gathering that takes place in the poster hall following the evening lectures. As with the lectures, the posters should present work that has not been previously published to a significant extent. All conferees are encouraged to submit and present posters. We will select 8-10 of the best poster abstracts for short oral presentations.

We recommend early application to the Biomineralization GRC as attendance is limited and the conference is regularly over-subscribed. We welcome applications from graduate students and young postdoctoral scientists to attend and present their research findings. A number of travel awards will be made based on submitted poster abstracts.


SUNDAY
2:00 pm - 11:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmMineral growth and organization I: Matrix-mineral relationships
7:40 pm - 8:00 pm Discussion leader: Arthur Veis (Northwestern University)
"Overview"
8:00 pm - 8:25 pm Anne George (University of Illinois at Chicago)
"Control of matrix proteins and biomimetic scaffolds for hydroxyapatie mineralization"
8:25 pm - 8:45 pm Discussion
8:45 pm - 9:10 pm Nils Kroger (Georgia Tech)
"Silica formation in diatoms: Lessons from the genome and control by polyamines and silaffins"
9:10 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMineral growth and organization II: In vitro models
9:00 pm - 9:15 am Discussion Leader: Patricia Dove (Virginia Tech)
"Overview"
9:15 am - 9:40 am Laurie Gower (University of Florida)
"Amorphous Precursors in Biomineralization: Does the Polymer-Induced Liquid-Precursor (PILP) Process Play a Role?"
9:40 am - 10:00 am Discussion
10:00 am Coffee Break / Group Photo
10:30 am - 10:55 am John Harding (University of Sheffield, UK)
"A computational approach to understanding crystal nucleation and growth"
10:55 am - 11:15 am Discussion
11:15 am - 11:40 am Paul Fenter (Argonne National Laboratory)
"Structure and reactivity of the mineral-solution interface"
11:40 am - 12:00 pm Discussion
12:00 pm - 12:05 pm Barbara Aichmayer (MPI of Colloids and Interfaces)
"The impact of organic inclusions on the structure and thermal stability of biomimetic calcite crystals"
12:05 pm - 12:10 pmDiscussion
12:10 pm - 12:15 pm Erika F. Merschrod (Memorial University)
"Structural effects of sugar acids on collagen-based mineralization matrices"
12:15 pm - 12:20 pmDiscussion
12:20 pm - 12:25 pm Emilie Pouget (Eindhoven University of Technology)
"Monitoring CaCO3 crystallization on a self-organized organic template: a 3D cryo-TEM study"
12:25 pm - 12:30 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmPathological Mineralization
7:30 pm - 7:45 pm Discussion Leader: Saeed Khan (University of Florida)
"Overview"
7:45 pm - 8:10 pm Mara Riminucci (University La Sapienza, Italy)
"Fibrous dysplasia - insights on abnormal mineralization of bone from clinical and experimental studies"
8:10 pm - 8:30 pm Discussion
8:30 pm - 8:55 pm Jose Luis Millan (Burnham Institute for Medical Research, USA)
"Pathogenesis of soft tissue calcification and the development of small molecule inhibitors for therapy"
8:55 pm - 9:15 pm Discussion
9:15 pm - 9:20 pm Felisa Berenguer (London Centre for Nanotechnology)
"Ptychographic Imaging of tissues: from tendon to bone"
9:20 pm - 9:25 pmDiscussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmBiomineral evolution and architecture in marine invertebrates
9:00 am - 9:15 am Discussion Leader: Jose Luis Arias (Chile)
"Overview"
9:15 am - 9:40 am Bernard Degnan (University of Queensland, Australia)
"Building and patterning molluscan shells with conserved and novel genes"
9:40 am - 10:00 am Discussion
10:00 am - 10:25 am Stéphanie Reynaud (Monaco Scientific Center, Monaco)
"Calcification of corals, effects of environmental parameters on proxies used for paleoclimatology"
10:25 am - 10:45 am Discussion
10:45 am Coffee Break
11:00 am - 11:25 am Ingrid Weiss (INM Leibniz-Institute for New Materials, Germany)
"Chitin and chitin synthase in mollusks"
11:25 am - 11:45 am Discussion
11:45 am - 12:10 pm Maggie Cusack (University of Glasgow, UK)
"Crystallography and crystal chemistry of brachiopods"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmFrom architecture to function
7:30 pm - 7:45 pm Discussion Leader: Peter Fratzl (Max Planck Institute Of Colloids and Interfaces)
"Overview"
7:45 pm - 8:10 pm Himadri S. Gupta (Max Planck Institute of Colloids and Interfaces, Germany)
"Understanding the origin of the toughness of mineralized tissues"
8:10 pm - 8:30 pm Discussion
8:30 pm - 8:55 pm Andrew Parker (Oxford University, UK)
"Photonic structures in nature"
8:55 pm - 9:15 pm Discussion
9:15 pm - 9:20 pm Rizhi Wang (University of British Columbia)
"Roles of Bone Hierarchical Structures in the Fracture Process, our Latest Observations"
9:20 pm - 9:25 pmDiscussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMacromolecular scaffolds for materials synthesis and organization
9:00 am - 9:15 am Discussion Leader: Arvind Kini (DOE Basic Energy Sciences)
"Overview"
9:15 am - 9:40 am Dirk Volkmer (Ulm University, Germany)
"Polymer Brushes for Biomimetic Crystallization"
9:40 am - 10:00 am Discussion
10:00 am - 10:25 am Tadashi Matsunaga (Tokyo University of Agriculture and Technology)
"Bacterial magnetite as an element in nanotechnology"
10:25 am - 10:45 am Discussion
10:45 am Coffee Break
11:00 am - 11:25 am Mark Young (Montana State University)
"Manipulating protein cages and viral capsids for control and synthesis of materials"
11:25 am - 11:45 am Discussion
11:45 am - 12:10 pm Ichiro Yamashita (Nara Institute of Science and Technology, Japan / Principal researcher, Advanced Technology Research Laboratories, Panasonic)
"Applications of protein supramolecules and bio-conjugates in Nanotechnology"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair; accompanied by "Biominerals in 3D" by James Weaver)
7:30 pm - 9:30 pmDefining the interactions and molecular contacts between organic and mineral components
7:30 pm - 7:45 pm Discussion Leader: Nita Sahai (University of Wisconsin-Madison)
"Overview"
7:45 pm - 8:10 pm Patrick Stayton (University of Washington)
"Imaging molecular recognition at the protein-mineral interface"
8:10 pm - 8:30 pm Discussion
8:30 pm - 8:55 pm Julian Gale (Curtin University of Technology, Australia)
"Exploring the role of ions and amino acids in accelerating the growth of minerals by simulation"
8:55 pm - 9:15 pm Discussion
9:15 pm - 9:20 pm Boaz Pokroy (Harvard University)
"Control of crystal orientation and shape by interface engineering"
9:20 pm - 9:25 pmDiscussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 11:05 amCellular controls on mineralization
9:00 am - 9:15 am Discussion Leader: Graeme Hunter (University of Western Ontario)
"Overview"
9:15 am - 9:40 am Lynda Bonewald (University of Missouri-Kansas City)
"The role of the osteoid-osteocyte and mature osteocyte in biomineralization"
9:40 am - 10:00 am Discussion
10:00 am - 10:25 am Ruedi Thalmann (Washington University)
"Function of otoconin90 and other proteins in the formation of mammalian otoconia"
10:25 am - 10:45 am Discussion
10:45 am Coffee Break
11:05 am - 12:30 pmTowards tissue engineering
11:05 am - 11:20 am Discussion Leader: David Kohn (U. Michigan)
"Overview"
11:20 am - 11:45 am Molly Stevens (Imperial College, UK)
"Nanotechnology approaches to tissue engineering"
11:45 am - 12:05 pm Discussion
12:05 pm - 12:10 pm Atsushi Arakaki (Tokyo University of Agriculture and Technology)
"Controlled formation of magnetite particles by the Mms6 protein of the magnetotactic bacterium, Magnetospirillum magneticum AMB-1"
12:10 pm - 12:15 pmDiscussion
12:15 pm - 12:20 pm Peta L. Clode (University of Western Australia)
"Uptake and incorporation of key compounds and metals in biomineralising marine invertebrates"
12:20 pm - 12:25 pmDiscussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session II
6:00 pmDinner
7:30 pm - 9:30 pmFinal evening session
7:30 pm - 7:35 pm Lia Addadi (Weizmann Institute, Israel)
"Introduction"
7:35 pm - 8:20 pm Steven Stanley (University of Hawaii)
"Biomineralization through time"
8:20 pm - 8:40 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

 
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