The Gordon Research Seminar “Cell Adhesion Receptors at the Cross-Roads of Cell Signaling Pathways: New Directions and Approaches” held in conjunction with the GRC meeting “Signaling by Cell Adhesion Receptors” will provide a unique forum for graduate student conference participants for the presentation and exchange of new ideas at the interface between cell signaling and cell adhesion receptors. The focus of the meeting will draw from many areas of Cell and Developmental Biology, Bio-Engineering, Bio-Medical Research, and Systems Biology. The Gordon Research Seminar will provide an outstanding opportunity for graduate students to present their work, receive constructive feedback, network with other graduate students in the field and facilitate future collaborations. Finally, the Gordon Research Seminar will serve to prepare students for the general meeting and create an atmosphere more conducive to higher levels of student participation and leadership throughout the subsequent GRC meeting
| SATURDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in |
| 4:45 pm - 5:00pm | Welcome by GRS Chairs |
| 4:00 pm - 5:00 pm | Poster Session - Odds |
| 5:00 pm - 6:00 pm | Poster Session - Evens |
| 6:00 pm | Dinner |
| 7:15 pm - 7:30 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:30 pm - 9:30 pm | New Directions and Approaches to Cell Adhesion Complex Function and Signaling |
| Discussion Leader: W. James Nelson (Stanford University) |
| 7:30 pm - 7:50 pm | Simon de Beco (Institut Curie - CNRS)
"Endocytosis is required for cadherin redistribution at mature adherens junctions" |
| 7:50 pm - 8:00 pm | Discussion |
| 8:00 pm - 8:20 pm | Vera Schulte (DWI an der RWTH Aachen e.V.)
"Surface Topography induces Fibroblast Adhesion and Spreading on two intrinsically non-fouling Biomaterials" |
| 8:20 pm - 8:30 pm | Discussion |
| 8:30 pm - 8:50 pm | Andrea Hartsock (Stanford University)
"Identifying the function of p120-catenin binding E-cadherin juxtamembrane domain" |
| 8:50 pm - 9:00 pm | Discussion |
| 9:00 pm - 9:20 pm | Monika Abedin (UC Berkeley)
"Cadherin evolution and the origin of animals" |
| 9:20 pm - 9:30 pm | Discussion |
| 9:45 pm - 11:30 pm | Poster Session |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Integration of Cell Adhesion Receptors and Cell Signaling |
| Discussion Leader: Clare Waterman (NIH) |
| 9:00 am - 9:20 am | Justin G. Peacock (Yale University)
"Fibronectin adhesion triggers microtubule delivery of Abl-related gene (Arg) to regulate actomyosin contractility and focal adhesion dynamics in migrating cells" |
| 9:20 am - 9:30 am | Discussion |
| 9:30 am - 9:50 am | Rosalyn A. Jurjus (George Washington University)
"Increased Migration and Altered Integrin Function Accompany Loss of Syndecan-1 (sdc-1) in Primary Dermal Fibroblasts Derived From Sdc-1 Deficient Mice" |
| 9:50 am - 10:00 am | Discussion |
| 10:00 am - 10:20 am | Steve Warner (Washington University)
"Opposing roles for Rho1 and Cdc42 in epithelial junctions and apical cell tension" |
| 10:20 am - 10:30 am | Discussion |
| 10:30 am | Coffee Break |
| 11:00 am - 11:15 am | Martine Van Miltenburg (Leiden University)
"Deletion of Focal adhesion kinase (FAK) disrupts mammary epithelial cell organization and contractility in vitro and in vivo" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:35 am | Botond Cseh (Centre Antoine Lacassagne)
"The Role of Cellular Fibronectin Variants in Vascular Endothelial Cells" |
| 11:35 am - 11:40 am | Discussion |
| 11:40 am - 11:55 am | Jennifer Leight (University of Pennsylvannia)
"Mechanical properties of the microenvironment modulate the oncogenic potential of TGF-beta" |
| 11:55 am - 12:00 pm | Discussion |
| 12:00 pm - 12:30 pm | Business Meeting |
| (Discuss request for a subsequent GRS; Nominations for the next Student/Post-doc Vice Chair(s) to work with GRC Chair (serving as mentor); Fill out Evaluation Forms) |
| 12:30 pm | Lunch |
| 1:30 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 2:00 pm. |