Gordon Research Conferences
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Conference Program
 
In Vivo Magnetic Resonance
July 20-25, 2008
Proctor Academy
Andover, NH

Magnetic resonance (MR) techniques provide powerful tools for studying living systems, from imaging of anatomy and metabolic function to detection and characterization of disease processes, and on spatial scales from individual cells to whole organs. The field of in vivo MR is dynamic and interdisciplinary, bringing together scientists with backgrounds in physics, chemistry, engineering, biology and medicine. This conference focuses on the latest developments in both methodology and applications, providing a unique venue for exchanging ideas and developing collaborations. Young investigators and students are particularly encouraged to apply. In addition to the invited talks and poster presentations, the Hot Topics presentations - selected from the poster abstracts - provide for inclusion of late-breaking developments. Topics include, but are not limited to: novel approaches for creating, detecting, and localizing the MR signal; applications of in vivo spectroscopy in disease and basic studies of metabolism; physical, chemical and biological mechanisms that affect the MR signal in vivo; development of new agents and approaches for manipulating the MR signal and contrast; functional MRI to study activation, blood flow and metabolism; and cellular function, from metabolism to gene expression to migration.


Contributors

SUNDAY
2:00 pm - 11:00 pmArrival and Check-in
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmPUMPING UP WITH HYPERPOLARIZED NUCLIDES
Discussion Leader: Sarah J. Nelson (University of California - San Francisco, USA)
7:40 pm - 8:20 pm Kevin M. Brindle (University of Cambridge, United Kingdom)
"Applications of hyperpolarized 13C magnetic resonance spectroscopic imaging in oncology"
8:20 pm - 8:35 pm Discussion
8:35 pm - 9:15 pm Jim M. Wild (University of Sheffield, United Kingdom)
"Sensitivity enhancement in hyperpolarized gas MRI"
9:15 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmSTRANGE AND EXOTIC
Discussion Leader: Petra Schmalbrock (Ohio State University, USA)
9:00 am - 9:45 am Philip W. Kuchel (University of Sydney, Australia)
"NMR spectral discrimination of enantiomers, and new tricks with cell suspensions, in a tunable-alignment system"
9:45 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:15 am Michael Garwood (University of Minnesota, USA)
"Frequency-swept MRI: no sound or echoes"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Gil Navon (Tel Aviv University, Israel)
"Insights into nerve compartments by H-2 DQF NMR"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session 1
6:00 pmDinner
7:30 pm - 9:30 pmMORE THAN MR - MULTI MODAL
Discussion Leader: Risto A. Kauppinen (Dartmouth Medical School, USA)
7:30 pm - 8:15 pm Sven Bestmann (University College London, United Kingdom)
"Imaging causal interactions using concurrent TMS and fMRI"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm T. Adrian Carpenter (University of Cambridge, United Kingdom)
"Combining high resolution PET and MRI in a single scanner for multi-modality preclinical imaging"
9:15 pm - 9:30 pm Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmLIGHTING UP WITH CONTRAST AGENTS
Discussion Leader: Brian K. Rutt (Robarts Institute, Canada)
9:00 am - 9:45 am Silvio Aime (University of Torino, Italy)
"High sensitivity probes for MR-Molecular Imaging investigations"
9:45 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:15 am Anna V. Moore (Massachusetts General Hospital & Harvard Medical School, USA)
"Contrast agents for cancer imaging"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Lon J. Wilson (Rice University, USA)
"Gadonanotubes as MRI contrast agents and more"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session 2
6:00 pmDinner
7:30 pm - 9:30 pmHOT TOPICS 1
Discussion Leader: Robia G. Paulter (Baylor College of Medicine, USA)
7:30 pm - 7:40 pm Nicholas Bock (National Institutes of Health)
"Manganese-enhanced magnetic resonance imaging (MEMRI) detects the V1/V2 border in the primate visual cortex"
7:40 pm - 7:45 pm Discussion
7:45 pm - 7:55 pm Timothy Duong (Emory University)
"Layer-specific anatomical, physiological and functional MRI of the retina"
7:55 pm - 8:00 pm Discussion
8:00 pm - 8:10 pm Lindsay Edwards (Oxford University)
"The effect of high-altitude on skeletal muscle energy metabolism: 31P NMR Results from the Caudwell Xtreme Everest expedition"
8:10 pm - 8:15 pm Discussion
8:15 pm - 8:25 pm Hisataka Kobayashi (NCI/NIH)
"Functional lymphatic imaging with nano-sized MRI or multi-modal contrast agents"
8:25 pm - 8:30 pm Discussion
8:30 pm - 8:40 pm Dario Longo (IFM, Italy)
"Optimizing In Vivo CEST Contrast Detection"
8:40 pm - 8:45 pm Discussion
8:45 pm - 8:55 pm Cynthia Massaad (Baylor College of Medicine)
"Mitochondrial Free Radicals Play a Critical Role in Alzheimer’s Disease Pathology"
8:55 pm - 9:00 pm Discussion
9:00 pm - 9:10 pm Elisenda Rodriguez (MGH - Harvard Medical School)
"MR sensors of myeloperoxidase activity. Characterization and mechanism of activation"
9:10 pm - 9:15 pm Discussion
9:15 pm - 9:25 pm Daniel Stuckey (University of Oxford)
"Bone marrow stem cells home to and remain in the infarcted rat heart, but fail to improve function: An in vivo MRI study"
9:25 pm - 9:30 pm Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmGETTING QUANTITATIVE - TISSUE BIOPHYSICS
Discussion Leader: Penny Anne Gowland (University of Nottingham, United Kingdom)
9:00 am - 9:45 am John C. Gore (Vanderbilt University, USA)
"Aspects of diffusion and relaxation in tissues"
9:45 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:15 am Sharon Peled (Brigham and Women's Hospital & Harvard Medical School, USA)
"DTI-based analysis of white matter"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Richard L. Ehman (Mayo Clinic - Minnesota, USA)
"Magnetic resonance elastography: update"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session 3
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:30 pmHOT TOPICS 2
Discussion Leader: Carolyn E. Mountford (Brigham and Women's Hospital & Harvard Medical School, USA)
7:30 pm - 7:40 pm Elisabeth Caparelli (Brookhaven National Laboratory)
"The Effects of 1 Hz rTMS in Brain Function - A Simultaneous TMS-fMRI Study of the Primary Visual Cortex Area"
7:40 pm - 7:45 pm Discussion
7:45 pm - 7:55 pm Andrew Kiruluta (Harvard University)
"NMR Diffractive Diffusion: q-space Imaging with Chirped Gradient Encoding"
7:55 pm - 8:00 pm Discussion
8:00 pm - 8:10 pm Yutong Liu (University of Nebraska Medical Center)
"An image warping technique to coregister MR images to histological sections based on thin-plate splines landmark optimization"
8:10 pm - 8:15 pm Discussion
8:15 pm - 8:25 pm Waqas Majeed (Georgia Institute of Technology)
"Spatiotemporal Dynamics of Low Frequency Fluctuations in Resting State BOLD fMRI"
8:25 pm - 8:30 pm Discussion
8:30 pm - 8:40 pm Shalom Michaeli (University of Minnesota)
"Nuclear Spin Relaxation along a Fictitious Field in a Tilting Rotating Frame"
8:40 pm - 8:45 pm Discussion
8:45 pm - 8:55 pm Karla Miller (Oxford University)
"Observation of Asymmetries in the SSFP Off-Resonance Profile"
8:55 pm - 9:00 pm Discussion
9:00 pm - 9:10 pm Petra Schmalbrock (The Ohio State University)
"On the Origin of Phase Reconstructed Imaging in Human Brain"
9:10 pm - 9:15 pm Discussion
9:15 pm - 9:25 pm Karin Shmueli (NINDS/NIH)
"Calculation of Human Brain Susceptibility Maps from High Resolution Phase Data at 7 T"
9:25 pm - 9:30 pm Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmIT AIN'T BRAIN
Discussion Leader: Xin Yu (Case Western Reserve University, USA)
9:00 am - 9:45 am Bruce A. Berkowitz (Wayne State University School of Medicine, USA)
"Seeing in the dark: prognostic phenotyping of retinopathy and its response to treatment with manganese-enhanced MRI"
9:45 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:15 am Kieran Clarke (University of Oxford, United Kingdom)
"What can 31P MRS tell us about heart failure?"
11:15 am - 11:30 am Discussion
11:30 am - 12:15 pm Felix W. Wehrli (University of Pennsylvania, USA)
"Multi-scale assessment of calcified tissue architecture and function by magnetic resonance"
12:15 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session 4
6:00 pmDinner
7:30 pm - 9:30 pmIT IS BRAIN - ACTIVATION
Discussion Leader: Karla L. Miller (University of Oxford, United Kingdom)
7:30 pm - 8:15 pm Wei Chen (University of Minnesota, USA)
"Great potential of in vivo MRS in studying cerebral bioenergetics associated with brain activation"
8:15 pm - 8:30 pm Discussion
8:30 pm - 9:15 pm Richard B. Buxton (University of California - San Diego, USA)
"Quantitative fMRI"
9:15 pm - 9:30 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDepart

 
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