Gordon Research Conferences
Meeting Details
Search:
  GO

Stem Cells & Cancer
Gordon Research Conference

Molecular Mechanisms Controlling Normal and Cancer Stem Cells

Dates

September 13-18, 2009

Location

Les Diablerets Conference Center
Les Diablerets, Switzerland

Organizers

Chair:
Maarten Van Lohuizen

Vice Chair:
Catriona Jamieson

Meeting Description

The 2009 second Gordon Conference on Stem cells and Cancer will present cutting-edge research on the cellular and molecular mechanisms controlling self-renewal and differentiation of both normal and cancerous stem cells. Emerging data indicates that cancer stem cells are responsible for the growth and spread of tumors. Expansion of normal stem cells is under tight genetic and epigenetic constraints. Cancer stem cells have escaped these limitations on expansion resulting in expansion of the self-renewing cell populations. The goals of this meeting are to present the most current research into the cellular and molecular biology of normal- and cancer stem cells. Topics that will be explored in this meeting are cancer stem cell niche signaling, the regulation of stem cell self-renewal in normal stem cells and cancer the cell of origin of cancer, Cellular reprogramming mechanisms, new markers for stem cells and cancer stem cells and cancer stem cells as therapeutic targets. The conference will bring together key investigators at the forefront of stem cell research and will provide opportunities for postdocs and graduate students to present their work in poster sessions and in a selected set of short talks. There will be ample opportunity for discussions and informal interactions to help promote cross-disciplinary interactions and foster collaborations between stem cell researchers world-wide.

Contributors

Meeting Program

SUNDAY
4:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pm Keynote Session on Normal and Cancer Stem Cells
7:40 pm- 8:00 pm Welcome: Maarten van Lohuizen (Netherlands Cancer Institute) and Catriona Jamieson (University of California, San Diego)
Discussion Leader: Catriona Jamieson (UCSD)
8:00 pm - 9:00 pmIrving L. Weissman (Stanford University)
"Normal and neoplastic Stem Cells"
9:00 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm Self-renewal and Cancer
Discussion Leader: Catriona Jamieson (UCSD)
9:00 am - 9:40 am Amy Wagers (Harvard University)
"Role of the niche in stem cell self-renewal, aging, and malignancy"
9:40 am - 10:00 am Discussion
10:00 am Coffee Break / Group Photo
10:30 am - 11:10 am Michael F. Clarke (Stanford University)
"Molecular regulation of stem cell self renewal in normal and diseased tissues"
11:10 am - 11:30 am Discussion
11:30 am - 12:10 pm Kristian Helin (Biotech Research and Innovation Centre, Kopenhagen)
"The role of Polycomb group proteins and histone demethylases in stem cells and cancer"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pm Reprogramming and induced pluripotent stem cells
Discussion Leader: Amy Wagers (Harvard University)
5:30 pm - 6:10 pm Austin Smith (Cambridge University)
"Natural and induced pluripotency"
6:10 pm - 6:30 pm Discussion
6:30 pm - 7:10 pm Dean Felsher (Stanford University)
"Cellular Senescence upon Oncogene Inactivation"
7:10 pm - 7:30 pm Discussion
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm Hemapoietic stem cells and Leukemia
Discussion Leader: Irving L. Weissman (Stanford University)
9:00 am - 9:40 am Peter Dirks (University of Toronto)
"Characterizing cancer stem cells in brain tumors from human and mouse"
9:40 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:10 am Gerald de Haan (Groningen University)
"Mapping transcriptional networks in hematopoietic stem cells"
11:10 am - 11:30 am Discussion
11:30 am - 12:10 pm Ronald DePinho (Dana Farber Cancer Institute)
"FoxOs in Cancer and Aging"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pm Solid tissue stem cells and Cancer
Discussion Leader: Catherine Booth (Head of Research, Epistem)
5:30 pm - 6:10 pm Jane Visvader (The Walter and Eliza Hall Institute of Medical Research)
"Dissecting the Mammary Epithelial Cell Hierarchy in Human and Mouse"
6:10 pm - 6:30 pm Discussion
6:30 pm - 7:10 pm Hans Clevers (Hubrecht Institute for Developmental Biology and Stem cell Research)
"Wnt, Lgr5 stem cells and colon cancer"
7:10 pm - 7:30 pm Discussion
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pm Niche signaling and Stem cell Control
Discussion Leader: Hans Clevers (Hubrecht Institute for Developmental Biology and Stem Cell Research)
9:00 am - 9:40 am Fiona Watt (Cambridge University)
"Extrinsic regulators of epidermal stem cell fate"
9:40 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:10 am Andreas Trumpp (DKFZ-Heidelberg)
"Dormancy in stem cells"
11:10 am - 11:30 am Discussion
11:30 am - 12:10 pm Shahragim Tajbakhsh (Pasteur Institute, Paris)
"Regulation of skeletal muscle stem cells during development and regeneration"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pm Mouse Models and Stem Cells
Discussion Leader: Ronald DePinho (Dana Farber Cancer Institute)
5:30 pm - 6:05 pm Anton Berns (The Netherlands Cancer Institute, Amsterdam)
"Mouse models for Lung Cancer"
6:05 pm - 6:15 pm Discussion
6:15 pm - 6:50 pm David Tuveson (Cancer Research UK Cambridge Research Institute)
"Developing Pancreatic Cancer"
6:50 pm - 7:00 pm Discussion
7:00 pm - 7:20 pm Short Talk: Thomas W. Davis (Associate Director of Oncology, PTC)
"Exploiting post-transcriptional regulation of Bmi-1 for drug discovery"
7:20 pm - 7:30 pm Discussion
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
8:30 am - 9:00 amBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
9:00 am - 12:30 pm Stem Cell profiling and (epi)genomics
Discussion Leader: Gerald de Haan (Groningen University)
9:00 am - 9:40 am Howard Chang (Stanford University)
"Programming chromatin states by long noncoding RNAs in cancer and development"
9:40 am - 10:00 am Discussion
10:00 am Coffee Break
10:30 am - 11:10 am Dirk Schübeler (Friedrich Miescher Institute, Basel)
"Distribution and function of DNA methylation and histone modifications during cellular differentiation"
11:10 am - 11:30 am Discussion
11:30 am - 12:10 pm Roel Nusse (Stanford University)
"Regulation of Wnts in tissue homeostasis and stem cell self-renewal"
12:10 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session
5:30 pm - 7:30 pm Therapeutics Against Cancer Stem Cells
Discussion Leader: Thomas W. Davis (Associate Director of Oncology, PTC)
5:30 pm - 6:05 pm 4 short talks from selected abstracts (10 min + 4 discussion)
6:05 pm - 6:15 pm Discussion
6:15 pm - 6:50 pm William Matsui (Sidney Kimmel Cancer Center at Johns Hopkins)
"Translating cancer stem cells to the clinic"
6:50 pm - 7:00 pm Discussion
7:00 pm - 7:20 pm Short Talk: Kelly L. Bennett (Oncology, Discovery Medicine, BMS)
"Targeting Cancer Stem Cells in Patients with Multiple Myeloma"
7:20 pm - 7:30 pm Discussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
© 2017 Gordon Research Conferences Search | Contact | Terms of Use | Privacy Policy | Follow us: Facebook Twitter