Conference Program
 
Bioinorganic Chemistry
Gordon Research Seminar
February 4-7, 2010
Four Points Sheraton / Holiday Inn Express
Ventura, CA
Chair:
Kathryn E. Cole
Related Meeting Information
The Bioinorganic Chemistry Gordon Research Seminar was held in conjunction with the Metals In Biology Gordon Research Conference. Please refer to the Metals In Biology GRC web page for more information.

The Gordon Research Seminar (GRS) in Bioinorganic Chemistry was originally developed in response to the annual over-subscription of the parent Metals in Biology Gordon Research Conference. Since its start in 1996, this GRS has become one of the leading forums for graduate students and postdoctoral researchers in bioinorganic chemistry to share their research and discuss the latest advancements in the field. This conference has gained considerable international recognition and attracts students and postdocs from all over the world. The unique overlapping session between the Bioinorganic GRS and the Metals in Biology GRC allows students and young researchers to interact with the leading principal investigators in the field.

Bioinorganic chemistry encompasses a wide range of topics including metal transport and homeostasis, metalloprotein structure and function, applications of metals in medicine and sensing, and metals in the environment. We invite and encourage students from any sub-discipline in Bioinorganic Chemistry to submit abstracts for poster or oral presentations. To be considered for an oral presentation for this meeting, please submit your application by October 5, 2009.

Note: This year, we would like to encourage all conference participants to bring their own coffee mugs to reduce the use of paper cups.

Contributors
THURSDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 8:45 pmJoint Session with the Metals in Biology GRC
7:30 pm - 8:30 pmKarl Wieghardt (Max Plank Institute, Mülheim)
"Coordinated radicals in biology and transition metal chemistry"
8:30 pm - 8:45 pmDiscussion
8:45 pmJoint Poster Session (presented by the Bioinorganic Chemistry GRS)
FRIDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmMetal Homeostasis and Transport
Discussion Leader: Pamela Riggs-Gelasco (College of Charleston)
9:15 am - 9:45 am Faith Jacobsen (Indiana University)
"The interplay between zinc and manganese homeostasis in Streptococcus Pneumoniae"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 am Harini Kaluarachchi (University of Toronto)
"Ni(II)-binding properties of the metallochaperone, SlyD"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 am Gregory Holmes-Hampton (Texas A&M University)
"Biophysical probes of iron metabolism in yeast mitochondria"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 am Swati Rawat (Wayne State University)
"Characterization of key players in the mitochondrial Fe-S cluster assembly pathway"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pm Kathryn Haas (Duke University)
"Spectroscopic studies of copper binding to N-terminal hCtr1 model peptides"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 8:55 pmBiomineralization and Bioinspired Materials
Discussion Leader: Trevor Douglas (Montana State University)
7:45 pm - 8:15 pm Lukmann Bawazer (University of California, Santa Barbara)
"Directed laboratory evolution of biomineralizing enzymes"
8:15 pm - 8:20 pm Discussion
8:20 pm - 8:50 pm Robert Radford (University of California, San Diego)
"Metal directed protein dimerization through hybrid coordination motifs"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:30 pmData Blitz
A series of 5-minute presentations
Rebecca Metzler (University of Wisconsin)
Olga Makhlynets (Tufts University)
Cesar Masitas Castillo (University of Louisville)
Shawn McGlynn (Montana State University)
Eric Smolensky (University of Minnesota)
SATURDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMetalloenzyme Kinetics and Mechanisms
Discussion Leader: Squire Booker (Pennsylvania State University)
9:15 am - 9:45 am Yan Kung (Massachusetts Institute of Technology)
"Crystallographic studies of CO to CO2 interconversion at a NiFeS cluster"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 am Gözde Ulas (Yale University)
"Studies on the water-oxidizing mechanism in Photosystem II with inhibitory zwitterions"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 am Megan Matthews (Pennsylvania State University)
"How aliphatic halogenases prevent competing hydroxylation"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 am Asha Rajapakshe (University of Arizona)
"The role of aromatic residues in the active site of human sulfite oxidase"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pm Charlie Olea (University of California, Berkeley)
"Chemical and structural consequences of heme distortion in H-NOX proteins"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 8:55 pmMetals in Medicine and Metallodrug Design
Discussion Leader: Debbie Crans (Colorado State University)
7:45 pm - 8:15 pm Dani Peri (Hebrew University of Jerusalem)
"Hydrolytic behavior and cytotoxicity of bis(phenolato) Ti(IV) complexes"
8:15 pm - 8:20 pm Discussion
8:20 pm - 8:50 pm Susana Vitorino (University of Birmingham)
"Dinuclear supramolecular rhodium (III) diimine complexes as DNA-binding cytotoxic drugs"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:30 pmData Blitz
A series of 5-minute presentations.
Setshaba Khanye (University of Cape Town)
Eric Null (University of Illinois)
Hugo Vazquez (Material Research Institute of the National Autonomous University of Mexico)
Chris Bergstrom (Princeton University)
Muhammad Hanif (University of Vienna)
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmBiomimetic Renewable Energy
Discussion Leader: Gary Brudvig (Yale University)
9:15 am - 9:45 am Alison Parkin (Oxford University)
"Characterisation and Application of the H2-oxidising enzymes from Escherichia coli"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 am Mackenzie Firer-Sherwood (Boston University)
"Redox chemistry of metalloproteins: using protein film voltammetry to examine electron transfer in multiheme cytochromes"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 am Mike Rose (CalTech)
"Reductive chemistry of Co- and Fe-based dimethylglyoxime (dmg) systems, and novel macrocyclic P4N2-Ni/Co complexes for hydrogen (H2) generation"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 am Arnab Dutta (Arizona State University)
"A bottom-up approach to the artificial [NiFe] hydrogenases: Synthesis of heterometallic [Ni-M] complexes in a peptide framework"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pm Nick Marshall (University of Illinois)
"Manipulating the Secondary Coordination Sphere to Tune the Reduction Potential of a Single Cupredoxin Beyond the Natural Range"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pmDepart
Funding for this conference was made possible in part by 5 R13 GM 074563 - 06 from the National Institute of General Medical Sciences. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
Last Updated: January 22, 2010