The Gordon Research Seminar on Protein Folding Dynamics is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange new data and cutting edge ideas.
The focus of this meeting is to enhance students' background on current techniques, theories and models of protein folding. Keynote lectures by senior scientists will provide an overview of the latest developments in the field and highlight outstanding questions. The meeting will provide the participants with a great opportunity to meet other young scientists in the field, present their work and enable future collaborations. The success of the previous Gordon Research Seminar in 2006 suggests this will be a vibrant and informative meeting.
| SATURDAY |
| 2:00 pm | Check-In Begins |
| 3:00 pm - 3:10 pm | Introductory Comments by GRC Site Staff / Welcome by the GRS Conference Chair |
| 3:10 pm - 4:00 pm | LOOKING FORWARD |
| 3:10 pm - 3:50 pm | Dave Thirumalai (University of Maryland)
"Outstanding Problems in Protein Folding" |
| 3:50 pm - 4:00 pm | Discussion |
| 4:00 pm - 6:00 pm | Poster Session I (last names A-M) |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | ADVANCES IN PROTEIN FOLDING THEORY AND SIMULATION |
| Discussion Leader: Lorna Dougan (University of Leeds) |
| 7:30 pm - 8:10 pm | Vijay Pande (Stanford University)
"Latest Developments in Computational Protein Folding" |
| 8:10 pm - 8:25 pm | Discussion |
| 8:25 pm - 8:40 pm | Katherine A. Ball (UC Berkeley)
"Amyloid-beta monomer and oligomer conformational ensembles" |
| 8:40 pm - 8:45 pm | Discussion |
| 8:45 pm - 9:00 pm | Edward O'Brien (Cambridge University)
"Tertiary structure formation occurs inside the ribosome exit port" |
| 9:00 pm - 9:05 pm | Discussion |
| 9:05 pm - 9:20 pm | Walraj S. Gosal (UT Southwestern Medical Centre)
"Deciphering evolutionary instructions for specifying protein fold and function" |
| 9:20 pm - 9:25 pm | Discussion |
| SUNDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | CURRENT STATE OF EXPERIMENTAL FOLDING AND DYNAMICS |
| Discussion Leader: Susan Marqusee (UC Berkeley) |
| 9:00 am - 9:40 am | Sheena Radford (University of Leeds)
"Overview of Current Experiments and Controversies" |
| 9:40 am - 9:55 am | Discussion |
| 9:55 am - 10:10 am | Derek R. Dee (University of Guelph)
"Prosegment-catalyzed folding as a model to study the nature of protein folding barriers" |
| 10:10 am - 10:15 am | Discussion |
| 10:15 am - 10:30 am | Jesse Dill (UC Berkeley)
"Optical Tweezers Study of an Unfolding Intermediate in E. coli RNase H" |
| 10:30 am - 10:35 am | Discussion |
| 10:35 am | Coffee Break |
| 11:00 am - 11:15 am | Candace M. Pfefferkorn (National Institutes of Health, NHLBI)
"Fluorescent probes of a-synuclein-and-membrane interactions: Insights into the role of membranes in aggregation" |
| 11:15 am - 11:20 am | Discussion |
| 11:20 am - 11:35 am | Gareth J. Morgan (University of Leeds)
"Optimizing Protein Stability In Vivo" |
| 11:35 am - 11:50 am | Discussion |
| 11:50 am - 12:05 pm | Steven A. Waldauer (Michigan State University)
"Measuring Intramolecular Diffusion During Protein Folding Using an Ultrarapid Microfluidic Mixer" |
| 12:05 pm - 12:10 pm | Discussion |
| 12:10 pm - 12:25 pm | Alessandro Borgia (University of Zurich)
"Localizing roughness on the free energy surface of protein folding" |
| 12:25 pm - 12:30 pm | Discussion |
| 12:30 pm | Lunch |
| 1:30 pm - 3:30 pm | Poster Session II (last names N-Z) |
| 3:30 pm | Gordon Research Seminar ends. For those attending the associated Gordon Research Conference, please check in at the GRC Office beginning at 4:00 pm. |