| SUNDAY |
| 2:00 pm - 9:00 pm | Arrival and Check-in (Office Closed 6:00 pm - 7:00 pm) |
| 6:00 pm | Dinner |
| 7:30 pm - 7:40 pm | Welcome / Introductory Comments by GRC Site Staff |
| 7:40 pm - 9:30 pm | Transmission of parasites |
| Discussion Leader: David Sacks (NIH, Bethesda, USA) |
| Sacks, David (NIH, Bethesda, USA) "Genetic exchange in Leishmania" |
| Bates, Paul (Liverpool School of Tropical Medicine, UK) "Transmission mechanisms of leishmaniasis" |
| Tait, Andy (University of Glasgow, UK) "Genetic exchange in African Trypanosomes" |
| MONDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Phenotypic variation, RNA and gene expression |
| Discussion Leader: Elisabetta Ullu (Yale University, USA) |
| Ullu, Elisabetta (Yale University, USA) "RNA interference and gene regulation in Trypanosoma brucei" |
| Llinas Manuel (Princeton University, USA) "Stage-specific transcriptional regulation by ApiAP2 proteins" |
| 10:15 am | Group Photo / Coffee Break |
| Lujan, Hugo (University of Cordoba, Argentina) "The RNAi machinery controls antigenic variation in the intestinal parasite Giardia lamblia" |
| Singh Upinder (Stanford University, USA) "An unusual repertoire of small RNAs and RNAi genes regulate gene expression in Entamoeba histolytica" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Host and parasite genetic variation in disease |
| Discussion Leader: Plowe Christopher (University of Maryland, USA) |
| Plowe Christopher (University of Maryland, USA) "Vaccine Resistant Malaria" |
| Hajduk Stephen (University of Georgia, USA) "Alternative mRNA editing expands T. brucei mitochondrial protein diversity" |
| Beverly Steve (Washington University, USA) "Genetic crossing as a tool for probing Leishmania virulence and tropisms" |
| TUESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Invasion and egress from host cells |
| Discussion Leader: Alan Cowman (WEHI, Melbourne) |
| Cowman Alan (WEHI, Melbourne) "Alternate merozoite invasion pathways used by P. falciparum to invade human erythrocytes" |
| Carruthers Vern (University of Michigan, Ann Arbor, USA) "Cell to cell transmission of Toxoplasma gondii" |
| 10:00 am | Coffee Break |
| Blackman Mike (National Institute of Medical Research, Mill Hill, UK) "Malarial proteases in invasion and egress" |
| Soldati Dominique (University of Geneva, Switzerland) "Mechanisms controlling glideosome function in apicomplexans" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Systems biology |
| Discussion Leader: Elisabeth Winzeler (Genomics Institute of the Novartis Research Foundation, San Diego) |
| Winzeler Elisabeth (Genomics Institute of the Novartis Research Foundation, San Diego) "Chemical and population genomics of malaria" |
| Kami Kim (Albert Einstein College of Medicine, New York, USA) "Using Epigenomics to Understand Gene Expression in Toxoplasma gondii" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| WEDNESDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Trafficking and organelle biogenesis |
| Discussion Leader: Boris Striepen (University of Georgia, Athens) |
| Striepen Boris (University of Georgia, Athens) "Biology of the apicomplexan plastid" |
| Haldar Kasturi (University of Notre Dame, USA) "The malaria secretome: from algorithms to essential functions" |
| 10:00 am | Coffee Break |
| Bastin Philippe (Institut Pasteur, Paris) "Constructing the trypanosome flagellum: a puzzle of 300 proteins" |
| Bangs Jay (University of Wisconsin-Madison, USA) "GPI's, sphingolipids, and secretory trafficking in African trypanosomes" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:00 pm - 7:30 pm | Business Meeting |
| (Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair) |
| 7:30 pm - 9:30 pm | Cell cycle and development |
| Discussion Leader: Keith Matthews (University of Edinburgh, UK) |
| Matthews Keith (University of Edinburgh, UK) "Regulating transmission by African trypanosomes" |
| Billker Oliver (The Wellcome Trust Sanger Institute, Cambridge, UK) "Regulation of malaria development in the mosquito" |
| Coppens Isabelle (Johns Hopkins University, Baltimore, USA) "Apicomplexan parasites: Insights into the developmental transformations of the sporozoite stage" |
| THURSDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am - 12:30 pm | Host Innate and Adaptive Immune Response |
| Discussion Leader: Elena Levashina (Institute of Molecular Biology, CNRS, Strasbourg) |
| Levashina Elena (Institute of Molecular Biology, CNRS, Strasbourg) "Central role of complement in the mosquito responses against Plasmodium parasites" |
| Hunter Christopher (University of Pennsylvania, Philadelphia, USA) "Imaging the immune response to Toxoplasma gondii" |
| 10:00 am | Coffee Break |
| Zavala Fidel (Johns Hopkins University, Baltimore, USA) "Homing and functional properties of liver-resident memory CD8+ T cells against malaria parasites" |
| Pays Etienne (Université Libre de Bruxelles, Belgium) "Molecular dialogue between Trypanosoma brucei and its mammalian hosts" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| 12:30 pm | Lunch |
| 1:30 pm - 4:00 pm | Free Time |
| 4:00 pm - 6:00 pm | Poster Session |
| 6:00 pm | Dinner |
| 7:30 pm - 9:30 pm | Novel intervention strategies |
| Discussion Leader: Mike Ferguson (University of Dundee) |
| Ferguson Mike (University of Dundee, UK) "Protein glycosylation in Trypanosoma brucei: host-parasite differences and therapeutic opportunities" |
| Ward Stephen (Liverpool School of Tropical Medicine, UK) "Targeting parasite uniqueness" |
| Short presentations selected from abstracts in consultation with Discussion Leader |
| FRIDAY |
| 7:30 am - 8:30 am | Breakfast |
| 9:00 am | Departure |