Gordon Research Conferences
PI_Conferences PI_Conferences_Current
Conference Program
 
 
 
QUICK SEARCH
GO
[ advanced search ]
 
 
 
Stereochemistry
August 1-6, 2010
Salve Regina University
Newport, RI
Chairs:
Jay S. Siegel & Scott J. Miller

Vice Chairs:
Michael J. Martinelli & Vittorio Farina
Application Deadline
Applications are no longer being accepted for this meeting. If you have been instructed to apply by the Conference Chair, please contact your Conference Coordinator for further instructions.

The arrangements of atoms in space determines chemistry and concomitantly defines stereochemistry. As such stereochemical principles underpin all that is chemically significant. The special character of chemistry comes from the ability to design and prepare new molecular entities from a base set of precepts that results in new catalysts, materials and medicinals. These same precepts allow us to rationalize the chemistry of biology and biologically active compounds. Although our fundamental understanding of stereochemistry may reduce to phenomena on the molecular scale and at the origins of life processes, its practical aspects extrapolate to ton-scale production and long sustainable technologies. It is a daunting task to cover this topic in one conference, but for 35 years the Stereochemistry GRC has been a leading forum for bringing chemists together to discuss issues of structure, property and synthesis.

The 2010 meeting will focus on 8 highly active subtopics of stereochemistry. A plenary program of 32 speakers and 7 moderators will form the basis for the conference. There will be also 2 poster sessions with associated "chalktalks" for new researchers. An open atmosphere for informal discussion events in the afternoon and late evening will be fostered.

SUNDAY
2:00 pm - 9:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 7:35 pmWelcome / Introductory Comments by GRC Site Staff
7:35 pm - 9:30 pmStereochemical Biology
Discussion Leader: Chris Seto (Brown)
7:35 pm - 8:05 pm Virginia Cornish (Columbia)
"The Ribosome Discriminates the Structure of the Amino Acid at It's Peptidyltransferase Center"
8:05 pm - 8:10 pm Discussion
8:10 pm - 8:45 pmSarah O'Connor (MIT)
"Stereochemistry in Indole Alkaloid Biosynthesis"
8:45 pm - 8:50 pm Discussion
8:50 pm - 9:25 pm Carole Bewley (NIH)
9:25 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmStereoselective Synthesis
Discussion Leader: Seth Herzon (Yale)
9:00 am - 9:35 amPhil Baran (TSRI)
"Aiming for the Ideal Synthesis"
9:35 am - 9:40 am Discussion
9:45 am - 10:20 am Shenming Ma (SIOC)
"Stereoselective Synthesis based on the Chemistry of Allenes"
10:20 am - 10:25 am Discussion
10:30 am Group Photo / Coffee Break
11:00 am - 11:35 amMatt Sigman (Utah)
"New Approaches to the de novo Design of Asymmetric Catalysts"
11:35 am - 11:40 am Discussion
11:45 am - 12:20 pm Erik Sorensen (Princeton)
"Strategic applications of double cyclizations in complex natural product synthesis"
12:20 pm - 12:25 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmMaterials Stereochemistry
Discussion Leader: James Canary (NYU)
7:30 pm - 8:05 pm Patrick Vaccaro (Yale)
"Absolute Stereochemical Configuration and Optical Activity: New Twists on an Old Topic"
8:05 pm - 8:10 pm Discussion
8:10 pm - 8:45 pmGeoff Coates (Cornell)
"New Catalysts for Stereoselective Polymerization"
8:45 pm - 8:50 pm Discussion
8:50 pm - 9:25 pm Kyoko Nozaki (Tokyo)
"Structural Control in Polymerization Utilizing CO or CO2"
9:25 pm - 9:30 pm Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmStereoselective Catalysis I
Discussion Leader: Abigail Doyle (Princeton)
9:00 am - 9:35 am Magnus Rueping (RWTH Aachen)
"Asymmetric Brønsted Acid Catalysis - Concepts and Applications"
9:35 am - 9:40 am Discussion
9:45 am - 10:20 amDan Yang (Hong Kong)
"Stereoselective Cyclization Reactions through Palladium and Silver Catalysis"
10:20 am - 10:25 am Discussion
10:30 am Coffee Break
11:00 am - 11:35 amTobias Ritter (Harvard)
"Late-Stage Fluorination"
11:35 am - 11:40 am Discussion
11:45 am - 12:20 pmTom Lectka (Johns Hopkins)
"Asymmetric alpha-Fluorination Leading to Serendipitous Discoveries"
12:20 pm - 12:25 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmResolution
Discussion Leader: Kurt Mislow (Princeton)
7:30 pm - 8:05 pm Chris Welch (Merck)
"Recent Studies on the Analysis and Purification of Stereoisomers Using Chromatography"
8:05 pm - 8:10 pm Discussion
8:10 pm - 8:45 pmBernhard Kaptein (DSM)
"Attrition enhanced deracemization under solid-liquid near-equilibrium conditions"
8:45 pm - 8:50 pm Discussion
8:50 pm - 9:25 pmMichael McBride (Yale)
"Grinding to Homochirality - The Mechanism of Viedma Ripening"
9:25 pm - 9:30 pm Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmStereoselectivity on Scale
Discussion Leader: Vittorio Farina (Johnson and Johnson Pharmaceutical R&D)
9:00 am - 9:35 am Joel Hawkins (Pfizer)
"Enantio- and Diastereoselective Hydrogenations of Pharmaceutical Intermediates"
9:35 am - 9:40 am Discussion
9:45 am - 10:20 am Jean-Michel Adam (Roche)
"Process Research towards a Scalable Route for a Roche Factor Xa Inhibitor"
10:20 am - 10:25 am Discussion
10:30 am Coffee Break
11:00 am - 11:35 amKlaus Ditrich (BASF)
"ChiPros® - Optically Active Intermediates on an Industrial Scale"
11:35 am - 11:40 am Discussion
11:45 am - 12:20 pm Chris Senanayake (Boehringer Ingelheim Pharmaceuticals, Inc)
"Asymmetric Synthetic Methodologies for Efficient Drug Development"
12:20 pm - 12:25 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
(Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair)
7:30 pm - 9:30 pmMedicinal Stereochemistry
Discussion Leader: Sarah Reisman (Caltech)
7:30 pm - 8:05 pmFrank Fang (Eisai)
"Process Research on Natural Product Based Drug Candidates"
8:05 pm - 8:10 pm Discussion
8:10 pm - 8:45 pmSheng Cui (Amgen)
"Development of a Practical Enantioselective Conjugate Alkynylation"
8:45 pm - 8:50 pm Discussion
8:50 pm - 9:25 pm Jonathan Elman (UC Berkeley)
"The Asymmetric Synthesis of Amines"
9:25 pm - 9:30 pm Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmStereoselective Catalysis II
Discussion Leader: Vy Maria Dong (Toronto)
9:00 am - 9:35 amMichael Krische (UT Austin)
"Formation of C-C Bonds via Catalytic Hydrogenation and Transfer Hydrogenation"
9:35 am - 9:40 am Discussion
9:45 am - 10:20 amMarisa Kozlowski (Penn)
"Asymmetric Oxidative Coupling and Claisen Rearrangements"
10:20 am - 10:25 am Discussion
10:30 am Coffee Break
11:00 am - 11:35 amHelma Wennemers (Basel)
"Bioinspired Asymmetric Catalysis"
11:35 am - 11:40 am Discussion
11:45 am - 12:20 pm Amir Hoveyda (Boston College)
"Learning from Nature through Catalyst Development"
12:20 pm - 12:25 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session I
6:00 pmDinner
7:30 pm - 9:30 pmSupramolecular Stereochemistry
Discussion Leader: Michael Martinelli (Arena)
7:30 pm - 8:05 pm David Sherman (Michigan)
"Structural Diversity and Enzymatic Versatility in Natural Product Biosynthesis"
8:05 pm - 8:10 pm Discussion
8:10 pm - 8:45 pmMakoto Fujita (Tokyo)
"Nanoscale Coordination Architectures: Self-Assembled Molecular Spheres"
8:45 pm - 8:50 pm Discussion
8:50 pm - 9:25 pmNed Seeman (NYU)
"DNA: Not Merely the Secret of Life"
9:25 pm - 9:30 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
Last Updated: July 22, 2010
 
© 2010 Gordon Research Conferences. All Rights Reserved.
Search | Contact | Privacy Policy | Terms of Use