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Chronobiology
Gordon Research Conference

Integration: From Molecule to Organism

Dates

June 12-17, 2011

Location

Renaissance Tuscany Il Ciocco
Lucca (Barga), Italy

Organizers

Chair:
Martha Merrow

Vice Chair:
Michael Rosbash

Meeting Description

The 2011 Gordon Conference on Chronobiology will present cutting-edge research on the molecular, cellular and behavioral aspects of circadian systems. The Conference will feature a wide range of topics, covering model organisms from prokaryotes, to plants, fungi, and animals, on levels from genes to behavior, using approaches from basic science and modelling to translational research. Invited speakers represent a variety of scientific disciplines, including biochemistry, molecular genetics, neurobiology, cell biology, epidemiology and mathematics. The Conference will bring together a collection of investigators who are at the forefront of their field, and will provide opportunities for junior scientists and graduate students to present their work in poster format and exchange ideas with leaders in the field. Some poster presenters will be selected for short talks. The collegial atmosphere of this Conference, with programmed discussion sessions as well as opportunities for informal gatherings in the afternoons and evenings, provides an avenue for scientists from different disciplines to brainstorm and promotes cross-disciplinary collaborations in the various research areas represented.

Contributors

Meeting Program

SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Check-in Desk Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKEYNOTE LECTURES: NEW METHODS AND NEW INSIGHTS
7:40 pm - 7:55 pm Discussion Leaders: Martha Gilette (University of Illinois) and John Hogenesch (University of Pennsylvania)
7:55 pm - 8:20 pm Scott Sternson (HHMI Janelia Farm)
"A neural circuit for control of feeding"
8:20 pm - 8:25 pm Discussion
8:25 pm - 8:50 pm David Rand (University of Warwick)
"Theoretical approaches to understanding clock design principles"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:20 pm Kazuhiro Yagita (Kyoto Prefectural University of Medicine)
"Chronogenesis and cellular differentiation"
9:20 pm - 9:25 pm Discussion
9:25 pm - 9:30 pm General Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTHE CLOCK IN THE CELL
9:00 am - 9:20 am Discussion Leader: Luis Larondo (Universidad Católica de Chile) and Carl Johnson (Vanderbilt University)
9:20 am - 9:45 am Akilesh Reddy (University of Cambridge)
"Peroxiredoxins and metabolic oscillations in the clockwork"
9:45 am - 9:50 am Discussion
9:50 am - 10:00 am Hot Topic Talk: Jerome Menet (Brandeis University)
"Genome-wide transcriptional regulation by CLK:BMAL1 in mouse liver"
9:50 am - 10:00 am Discussion
10:00 am Coffee Break / Group Photo
10:30 am - 10:55 am Juergen Ripperger (University of Fribourg)
"Impact of dynamic histone H3.3 exchange on the mammalian circadian oscillator"
10:55 am - 11:00 am Discussion
11:00 am - 11:25 am Maria Mittag (University of Jena)
"The clockwork in the green biflagellate alga Chlamydomonas"
11:25 am - 11:30 am Discussion
11:30 am - 11:55 am Michael Brunner (University of Heidelberg)
"Generation of evening specific transcription in Neurospora"
11:55 am - 12:00 pm Discussion
12:00 pm - 12:10 pm Hot Topic Talk: Francois Rouyer (CNRS)
"A CULLIN-3 Ubiquitination Complex Controls TIMELESS Oscillations in the Drosophila Circadian Clock"
12:10 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session I
5:30 pm - 7:30 pmTHE CLOCK IN THE BRAIN
5:30 pm - 5:45 pm Discussion Leaders: Mary Harrington (Smith College) and TBA
5:45 pm - 6:10 pm Daniel Forger (University of Michigan)
"Multi-scale Complexity within the SCN"
6:10 pm - 6:15 pm Discussion
6:15 pm - 6:40 pm Stephan Michel (University of Leiden)
"Aging of the SCN neuronal network; implications for the regulation of sleep and behavioral activity"
6:40 pm - 6:45 pm Discussion
6:45 pm - 7:10 pm Michael Nitabach (Yale University)
"Allocation of Crepuscular Activity by a Homotypic Neuropeptide Relay"
7:10 pm - 7:15 pm Discussion
7:15 pm - 7:30 pm General Discussion
8:00 pmDinner
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTHE RETINA AND THE CLOCK
9:00 am - 9:20 am Discussion Leaders: Samer Hatter (Johns Hopkins University) and Howard Cooper (Lyon)
9:20 am - 9:45 am Doug McMahon (Vanderbilt University)
"The Retinal Circadian Clock: Keeping the Eye On Time"
9:45 am - 9:50 am Discussion
9:50 am - 10:00 am Hot Topic Talk: Laura Lande-Diner (Harvard Medical School)
"TRAP150: A circadian interface between CLOCK-BMAL1 and the general transcription machinery"
10:00 am Coffee Break
10:30 am - 10:55 am Tim Brown (University of Manchester)
"Melanopsin ganglion cell contributions to sensory coding in central targets"
10:55 am - 11:00 am Discussion
11:00 am - 11:25 am Russell Foster (University of Oxford)
"Light input to the clock: Multiple signalling pathways"
11:25 am - 11:30 am Discussion
11:30 am - 11:55 am Charles Allen (Oregon State University)
"Signaling Mechanisms Mediating Suprachiasmatic Responses to Light Input"
11:55 am - 12:00 pm Discussion
12:00 pm - 12:10 pm Hot Topic Talk: Felix Naef (University of Lausanne)
"Fast stochastic switches underlie transcriptional bursting of circadian promoters in single mammalian cells"
12:10 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session I
5:30 pm - 7:30 pmENTRAINMENT OF THE CLOCK
5:30 pm - 5:45 pm Discussion Leader: Michael Rosbash (Brandeis University) and C. Kyriacou (Leicester University)
5:45 pm - 6:10 pm TBA
6:10 pm - 6:15 pm Discussion
6:15 pm - 6:40 pm Charlotte Helfrich-Foerster (University of Wuerzburg)
"Old mutants in new light"
6:40 pm - 6:45 pm Discussion
6:45 pm - 7:10 pm Ralf Stanewsky (Queen Mary University)
"Temperature entrainment of the clock in the fly"
7:10 pm - 7:15 pm Discussion
7:15 pm - 7:30 pm General Discussion
8:00 pmDinner
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTHE EXPANDING CLOCK NETWORK IN THE CELL
9:00 am - 9:20 am Discussion Leaders: Jennifer Loros (Dartmouth Medical School) and Leslie Griffith (Brandeis University)
9:20 am - 9:45 am Deborah Bell-Pedersen (Texas A&M University)
"Clock regulation of conserved MAPK pathways"
9:45 am - 9:50 am Discussion
9:50 am - 10:00 am Hot Topic Talk: Fumika Hamada (Cincinnati Children's Hospital Medical Center)
"The circadian clock sets body temperature rhythm in Drosophila"
10:00 am Coffee Break
10:30 am - 10:55 am Carla Green (University of Texas Southwestern)
"Circadian post-transcriptional control of metabolism"
10:55 am - 11:00 am Discussion
11:00 am - 11:25 am Hitoshi Okamura (Kyoto University)
"Dysregulated, cell-specific ccg's lead to disease"
11:25 am - 11:30 am Discussion
11:30 am - 11:55 am Michael Rust (University of Chicago)
"Resetting the Cyanobacterial Clock with Nucleotides"
11:55 am - 12:00 pm Discussion
12:00 pm - 12:10 pm Hot Topic Talk: Patrick Emery (University of Massachusetts Medical School)
"GW182 modulates PDF-R signaling and circadian behavior in Drosophila"
12:10 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session II
5:30 pm - 7:30 pmFITNESS AND THE CIRCADIAN CLOCK
5:30 pm - 5:45 pm Discussion Leaders: Serge Daan (University of Groningen) and Barbara Helm (Konstanz University and Max Planck Institute for Ornithology)
5:45 pm - 6:10 pm Seth Davis (Max Planck Institute for Plant Breeding Research)
"Stress signaling as an input and an output of the plant circadian clock"
6:10 pm - 6:15 pm Discussion
6:15 pm - 6:40 pm Jadwiga Giebultowicz (Oregon State University)
"The importance of circadian rhythms in preventing proteotoxicity during aging"
6:40 pm - 6:45 pm Discussion
6:45 pm - 7:10 pm Amita Sehgal (University of Pennsylvania)
"Circadian clocks and aging in Drosophila"
7:10 pm - 7:15 pm Discussion
7:15 pm - 7:30 pm General Discussion
7:30 pm - 8:00 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
8:00 pmDinner
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmTHE CLOCK IN HEALTH AND DISEASE: TRANSLATIONAL RESEARCH
9:00 am - 9:15 am Discussion Leaders: Till Roenneberg (University of Munich Medical School) and Maria Paz y Hidalgo (UFRGS, Brazil)
9:15 am - 9:45 am Debra Skene (University of Surrey)
"Lighting for older people: The challenges"
9:45 am - 9:50 am Discussion
9:50 am - 10:00 am Hot Topic Talk: Darwin Jeyaraj (Case Western Reserve University School of Medicine)
"Circadian rhythms govern cardiac repolarization and arrhythmogenesis"
10:00 am Coffee Break
10:30 am - 10:55 am Eva Schernhammer (Harvard University)
"Circadian-related genetic and environmental risk factors for cancer"
10:55 am - 11:00 am Discussion
11:00 am - 11:25 am Kenneth Wright (University of Colorado, Boulder)
"Circadian and sleep-wakefulness regulation of energy expenditure in humans"
11:25 am - 11:30 am Discussion
11:30 am - 11:55 am Marina Antoch (Roswell Park Cancer Insitute)
"A cross-talk between the circadian and NFkB pathways"
11:55 am - 12:00 pm Discussion
12:00 pm - 12:10 pm Hot Topic Talk: Frederic Gachon (University of Lausanne)
"The circadian clock coordinates ribosome biogenesis in mouse liver"
12:10 pm - 12:30 pm General Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 5:30 pmPoster Session II
5:30 pm - 7:30 pmINTEGRATION AND SYNTHESIS
5:30 pm - 5:45 pm Discussion Leaders: Gene Block (UCLA) and Rae Silver (Columbia University)
5:45 pm - 6:10 pm Joseph Takahashi (University of Texas Southwestern)
"Genetic analysis of circadian clocks in mammals"
6:10 pm - 6:15 pm Discussion
6:15 pm - 6:40 pm Andrew Millar (University of Edinburgh)
"Simple and complex clocks"
6:40 pm - 6:45 pm Discussion
6:45 pm - 7:10 pm William Schwartz (University of Massachusetts)
"Running in the night"
7:10 pm - 7:15 pm Discussion
7:15 pm - 7:30 pm General Discussion
8:00 pmDinner
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
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