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Dendrites: Molecules, Structure & Function
March 13-18, 2011
Ventura Beach Marriott
Ventura, CA
Chairs:
Erin M. Schuman & Dan Johnston

Vice Chairs:
Steven Siegelbaum & Rachel Wong
Related Meeting Information
The Dendrites: Molecules, Structure & Function Gordon Research Conference was held in conjunction with the Dendrites: Molecules, Structure & Function Gordon Research Seminar. Please refer to the Dendrites: Molecules, Structure & Function GRS web page for more information.

Most of the brain's computing occurs in neuronal dendrites. Dendrites receive and integrate thousands of synaptic inputs from other nerve cells. Although dendrites were discovered over a century ago, there has been a dramatic resurgence of interest in these remarkable and highly complex structures. This has led to exciting new discoveries on many aspects of dendrites, spurred by recent technical developments - including advances in imaging, electrophysiology, and molecular biology. As a consequence, dendrites are now viewed as a field of study in and of themselves, and promise to unite and shed new light on disparate fields such as membrane trafficking, development, synaptic and intrinsic plasticity, and disease. This Gordon Conference will crystallize the latest developments in dendritic research, from their morphology and development, through to their electrical and computational properties. The conference should be of interest to all researchers and students in neuroscience, as well as anyone who is interested in normal and abnormal brain function.

Contributors
SUNDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:45 pm)
6:00 pmDinner
7:30 pm - 7:40 pmWelcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pmKeynote Lecture
Discussion Leader: Erin Schuman (MPI-Frankfurt)
7:45 pm - 9:00 pmJosh Sanes (Harvard)
"Three Stories about Retinal Dendrites"
9:00 pm - 9:30 pm Discussion
MONDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDendrite Development
Discussion Leader: Rachel Wong (University of Washington)
9:00 am - 9:25 amAnirvan Ghosh (UCSD)
"Mechanisms of Synapse Specificity"
9:25 am - 9:35 am Discussion
9:35 am - 10:00 amDeanna Benson (Mt. Sinai Medical Center)
"Testing the capacity for local protein synthesis during dendrite development"
10:00 am - 10:10 am Discussion
10:10 am Group Photo / Coffee Break
10:40 am - 11:05 amYishi Jin (UCSD)
"Dendritic Extrasynaptic Signaling Regulates C. elegans Motor Circuit"
11:05 am - 11:15 am Discussion
11:15 am - 11:40 amKim McAllister (UC Davis)
"Synaptic activity and immune molecules interact to regulate synapse formation and dendrite growth in cortical neurons"
11:40 am - 11:50 am Discussion
11:50 am - 12:05 pm Short-talk: TBA
12:05 pm - 12:15 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmDendrite Development II
Discussion Leader: Yishi Jin (UCSD)
7:35 pm - 8:00 pmKim Tolias (Baylor)
"A novel Rac GTPase Regulatory Complex controlling Synaptic and Dendritic Development"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:35 pmAzad Bonni (Harvard)
"Regulation of Dendrite Morphogenesis by Ubiquitin Signaling"
8:35 pm - 8:45 pm Discussion
8:45 pm - 9:10 pmHolli Cline (Scripps San Diego)
"The Dynamic Connectome"
9:10 pm - 9:20 pm Discussion
TUESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmNeuronal Polarity
Discussion Leader: Antonella Riccio (MRC-London)
9:05 am - 9:30 amDon Arnold (USC)
"An Actin/Myosin-based Model of Polarized Targeting"
9:30 am - 9:40 am Discussion
9:40 am - 9:55 am Short talk: TBA
9:55 am - 10:05 am Discussion
10:05 am Coffee Break
10:30 am - 10:55 amBettina Winckler (Univ. of Virginia)
"Somatodendritic Endosomes at the Crossroads of Membrane Traffic"
10:55 am - 11:05 am Discussion
11:05 am - 11;30 amFranck Polleux (Scripps-San Diego)
"Molecular Mechanisms Underlying Neuronal Polarization in vivo"
11:30 am - 11:40 am Discussion
11:40 am - 11:55 amShort talk: TBA
11:55 am - 12:05 pm Discussion
12:05 pm - 12:20 pm Short talk: TBA
12:20 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmConnectivity
Discussion Leader: Kristen Harris (UT Austin)
7:35 pm - 8:00 pmWinfried Denk (MPI Heidelberg)
"Dendro-dendritic wiring in the direction selective circuit of the retina"
8:00 pm - 8:10 pm Discussion
8:10 pm - 8:35 pmRafa Yuste (Columbia)
"Dendritic spines and linear networks"
8:35 pm - 8:45 pm Discussion
8:45 pm - 9:10 pm Zoltan Nusser (Hungary)
"Unique subcellular compartment-specific distribution patterns of voltage-gated ion channel subtypes"
9:10 pm - 9:20 pm Discussion
WEDNESDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDendritic Integration I
Discussion Leader: Nelson Spruston (Northwestern)
9:05 am - 9:30 amJeff Magee (JFRC)
"Input comparison in the distal dendrites of pyramidal neurons"
9:30 am - 9:40 am Discussion
9:40 am - 9:55 am Short talk: TBA
9:55 am - 10:05 am Discussion
10:05 am Coffee Break
10:30 am - 10:55 amJeff Isaacson (UCSD)
"Dendritic inhibition in Olfactory Cortex"
10:55 am - 11:05 am Discussion
11:05 am - 11:30 amMichael Hausser (UCL)
"Dendritic Computation"
11:30 am - 11:40 am Discussion
11:40 am - 12:05 pm Greg Stuart (ANU)
"Electrical Properties of Dendritic Spines"
12:05 pm - 12:15 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 9:30 pmDendritic Integration II
Discussion Leader: Michael Hausser (UCL)
7:30 pm - 7:55 pmPeter Jonas (IST Vienna)
"The Active Dendrites of CA3 Pyramidal Neurons"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:30 pmNace Golding (UT Austin)
"Shaping of Excitatory and Inhibitory Synaptic Inputs by Kv1 Potassium Channels"
8:30 pm - 8:40 pm Discussion
8:40 pm - 9:05 pmArthur Konnerth (Munich)
"Synaptic Activation of Dendrites and Spines in Sensory Cortex Neurons in vivo"
9:05 pm - 9:15 pm Discussion
THURSDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmDendritic Spines
Discussion Leader: Zoltan Nusser (Hungary)
9:05 am - 9:30 amKristen Harris (UT Austin)
"Structural Substrates of Synaptic Scaling Among Dendritic Spines during LTP"
9:30 am - 9:40 am Discussion
9:40 am - 10:05 amKaren Zito (UC Davis)
"Regulation of Dendritic Spine Growth and Stability"
10:05 am - 10:15 am Discussion
10:15 am Coffee Break
10:35 am - 11:00 amBernardo Sabatini (Harvard Medical School)
"Mechanisms of activity-dependent spineogenesis and synaptogenesis in developing cortex"
11:00 am - 11:10 am Discussion
11:10 am - 11:35 amMorgan Sheng (Genentech)
"Life and Death of Synapses"
11:35 am - 11:45 am Discussion
11:45 am - 12:00 pm Short talk: TBA
12:00 pm - 12:10 pm Discussion
12:10 pm - 12:25 pm Short talk: TBA
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 9:30 pmLocal Processing and Plasticity
Discussion Leader: Steve Siegelbaum (Columbia)
7:30 pm - 7:55 pmAntonella Riccio (MRC-UCL)
"Epigenetic regulation of gene expression in developing neurons"
7:55 pm - 8:05 pm Discussion
8:05 pm - 8:20 pmShort talk: TBA
8:20 pm - 8:25 pm Discussion
8:25 pm - 8:50 pmSam Wang (Princeton)
"Synaptic Learning Rules: from Molecules to Behavior (and back)"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:20 pmLily Jan (UCSF)
"Synaptic regulation of K+ Channel Local Processing"
9:20 pm - 9:30 pm Discussion
FRIDAY
7:30 am - 8:30 amBreakfast
9:00 amDeparture
Funding for this conference was made possible (in part) by (R13 MH079632) from the National Institute of Mental Health. The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S. Government.
 
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