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Bioinorganic Chemistry
Gordon Research Seminar
February 3-6, 2011
Four Points Sheraton / Holiday Inn Express
Ventura, CA
Chair:
Christine M. Phillips-Piro
Related Meeting Information
The Bioinorganic Chemistry Gordon Research Seminar was held in conjunction with the Metals in Biology Gordon Research Conference. Please refer to the Metals in Biology GRC web page for more information.

The Gordon Research Seminar (GRS) in Bioinorganic Chemistry was originally developed in response to the annual over-subscription of the parent Metals in Biology Gordon Research Conference. Since its start in 1996, this GRS has become one of the leading forums for graduate students and postdoctoral researchers in bioinorganic chemistry to share their research and discuss the latest advancements in the field. This conference has gained considerable international recognition and attracts students and postdocs from all over the world. The unique overlapping session between the Bioinorganic GRS and the Metals in Biology GRC allows students and young researchers to interact with the leading principal investigators in the field.

Bioinorganic chemistry encompasses a wide range of topics including metal transport and homeostasis, metalloprotein structure and function, metals in the environment, and bioinorganic technique and application development. We invite and encourage students from any sub-discipline in Bioinorganic Chemistry to submit abstracts for poster or oral presentations. To be considered for an oral presentation for this meeting, please indicate in your interest in the “Activities” description of your application and apply for the conference by October 8, 2010. If you have any questions, please feel free to contact the conference chair, Christine Phillips, or the vice chair, Robert Radford.

Additionally, three optional, informal panel discussions will take place during the GRS weekend. The topics for these discussions are listed below:

  • Fixing the Pipeline: Attracting Future Faculty - Thursday, Feb. 3rd at 4pm
  • Applying for a Postdoctoral Research Position - Friday, Feb. 4th at 4pm
  • Careers in Bioinorganic Chemistry - Saturday, Feb. 5th at 4pm
Contributors
THURSDAY
4:00 pm - 8:00 pmArrival and Check-in (Office Closed 6:00 pm - 7:00 pm)
6:00 pmDinner
7:30 pm - 9:30 pmJoint Session with the Metals in Biology GRC
Discussion Leader: Ann Walker (U. Arizona)
7:30 pm - 8:30 pmAlison Butler (University of California, Santa Barbara)
"Elements of the High Seas: The Bioinorganic Chemistry in the Marine Environment"
8:30 pm - 8:45 pm Discussion
8:45 pmJoint Poster Session (presented by the Bioinorganic Chemistry GRS)
FRIDAY
7:30 am - 8:30 amBreakfast
8:30 amGroup Photo
9:00 am - 12:30 pmMetals in Extreme Environments
Discussion Leader: Ann Valentine (Yale University)
9:15 am - 9:45 amTyler Grove (Pennsylvania State University)
"A Radically Different Mechanism for S-adenosylmethionine-dependent Methyltransferases Exhibited by the Antibiotic Resistance Protein Cfr and its Homologue RlmN"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 amTrinity Hamilton (Montana State University)
"Biological Nitrogen Fixation in the Yellowstone Geothermal Complex"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 amYan Kung (MIT)
"Structural investigations of a metalloenzyme complex enabling microbial growth on CO2"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 amJoseph Braymer (University of Michigan)
"Development of Bifunctional Small Molecules that Target Metal-Amyloid-β Species"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pmBenoit Desguin (Universite Catholique de Louvain)
"Biochemical characterization of the lactate racemase of Lactobacillus plantarum: a new member of the nickel-enzyme family"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:30 pm - 8:55 pmBioinorganic Methods and Technique Development
Discussion Leader: Sean Elliott (Boston University)
7:45 pm - 8:15 pmMichael Winter (University of California, Berkeley)
"Heme Protein Receptors for Diatomic Gas Sensing and Signaling"
8:15 pm - 8:20 pm Discussion
8:20 pm - 8:50 pmJeffrey Brodin (University of California, San Diego)
"Construction of highly ordered protein-based materials using coordination chemistry"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:30 pmData Blitz
A series of 5-minute presentations
  • Joshua Hayden (Carnegie Mellon University)
  • Chelsea McIntosh (Arizona State University)
  • Abdullahi Sobola (Rhodes University)
  • Bruno Cardey (University of Tromsø)
  • Katarzyna Grubel (Utah State University)
SATURDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmModeling and Characterizing Metalloenzyme Active Sites
Discussion Leader: Andy Borovik (University of California, Irvine)
9:15 am - 9:45 amKatie Ellis (Boston University)
"Investigating electron transfer and catalysis of bacterial cytochrome c peroxidases"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 amAlexey Silakov (Max-Planck Institute for Bioinorganic Chemistry)
"Electronic structure of the H-cluster in [FeFe] hydrogenase"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 amMary Krause (Kansas University)
"Site-specific chiral inversion within a Ni-tripeptide complex generates a Ni-SOD mimic"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 amAalo Gupta (University of Minnesota)
"Synthesis and Characterization of O2-Reactive Bioinspired Cu(I) complexes and their Intermediates"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pmDavid Lacy (University of California, Irvine)
"Synthesis and Reactivity of High-Spin Non-Heme Oxoiron(IV) complexes"
12:25 am - 12:30 pm Discussion
12:30 pmLunch
1:30 pm - 4:00 pmFree Time
4:00 pm - 6:00 pmPoster Session
6:00 pmDinner
7:00 pm - 7:30 pmBusiness Meeting
Nominations for the next Vice Chair; Fill out Conference Evaluation Forms; Discuss future Site & Scheduling preferences; Election of the next Vice Chair
7:30 pm - 8:55 pmMetal Homeostasis in the Cell and Environment
Discussion Leader: John Magyar (Barnard)
7:45 pm - 8:15 pmColin Correnti (University of Washington)
"Siderocalins: Siderophore Binding Sentinels of the Innate Immune System"
8:15 pm - 8:20 pm Discussion
8:20 pm - 8:50 pmCarl Patterson (University of Durham)
"The discernment of metals by a set of bacterial transcriptional regulators"
8:50 pm - 8:55 pm Discussion
8:55 pm - 9:30 pmData Blitz
A series of 5-minute presentations
  • Maria-Eirini Pantelia (Max-Planck Institute for Bioinorganic Chemistry)
  • Lars Plate (University of California, Berkeley)
  • Sambuddha Banerjee (Duke)
  • Ning Li (Pennsylvania State University)
  • Pamela Sontz (Caltech)
SUNDAY
7:30 am - 8:30 amBreakfast
9:00 am - 12:30 pmMetal Clusters and Cofactors in Biology
Discussion Leader: Sonya Franklin (Monsanto)
9:15 am - 9:45 amHeather Williamson (Caltech)
"Introducing Multiple Redox-active Residues in Pseudomonas aeruginosa azurin to Facilitate Ultrafast Intra-molecular Photo-oxidation"
9:45 am - 9:50 am Discussion
9:50 am - 10:20 amKim Chung (University of Toronto)
"Capturing the nickel insertion complex of E. coli [NiFe] hydrogenase"
10:20 am - 10:25 am Discussion
10:25 am - 10:45 am Coffee Break
10:45 am - 11:15 amJoseph Cotruvo (MIT)
"Mechanism of assembly of the dimanganese(III)-tyrosyl radical cofactor of E. coli class Ib ribonucleotide reductase in vitro and in vivo"
11:15 am - 11:20 am Discussion
11:20 am - 11:50 amAvneesh Saini (University of South Carolina)
"SufD and SufC ATPase activities are required for iron acquisition during in vivo Fe-S cluster formation on SufB"
11:50 am - 11:55 am Discussion
11:55 am - 12:25 pmAnja Pomowski (University of Freiburg)
"Structure of purple nitrous oxide reductase - New Insights into CuZ"
12:25 pm - 12:30 pm Discussion
12:30 pmLunch
1:30 pmDeparture
 
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